GW 3965 HYDROCHLORIDE

Product Name: GW 3965 HYDROCHLORIDE
CAS No.: 405911-17-3
Chemical Name: GW 3965 HYDROCHLORIDE
Synonyms: CS-742;GW3965 HCl;GW3965 HCl Salt;W 3965 HYDROCHLORIDE;GW3965 hydrochloride, >=98%;GW-3965 hydrochloride GW3965;GW 3965 HYDROCHLORIDE; GW-3965 HYDROCHLORIDE;;3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…;2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylet...;3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride
CBNumber: CB5972490
Molecular Formula: C33H31ClF3NO3.HCl
Formula Weight: 0
MOL File: 405911-17-3.mol

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GW 3965 HYDROCHLORIDE Property

storage temp.: Store at -20°C
solubility: DMSO: ≥20mg/mL
form: powder
color: white
InChIKey: NMPUWJFHNOUNQU-UHFFFAOYSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G6295
Product name: GW3965 hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $206
Updated: 2024/03/01

Sigma-Aldrich

Product number: G6295
Product name: GW3965 hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $702
Updated: 2024/03/01

Cayman Chemical

Product number: 10054
Product name: GW 3965 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 10054
Product name: GW 3965 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 10054
Product name: GW 3965 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $175
Updated: 2024/03/01

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GW 3965 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.

Biochem/physiol Actions

GW3965 is a liver X receptor full agonist on hLXRα and hLXRβ. GW3965 has an EC50 = 125 nM in a cell-free ligand-sensing assay of LXRα and profiles as a full agonist on hLXRα and hLXRβ in cell-based assays with EC50 = 190 nM and 30 nM, respectively. It is orally active in mice. When screened against a panel of nuclear receptors, it cross-reacted with only the pregnane X receptor (PXR). The literature agonist, T0901317 (Tularik), had an EC50 = 60 nM and 85 nM in the cell-free and cell-based assays, respectively.

storage

Desiccate at RT

GW 3965 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GW 3965 HYDROCHLORIDE Suppliers

China 102 India 2 Switzerland 1 The Netherlands 1 United Kingdom 2 United States 15 Global 123

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19179
Advantage: 64

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8878
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
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Country: China
ProdList: 25003
Advantage: 65

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Shanghai Run-Biotech Co., Ltd.

Tel: 021-57171705 13817537615
Fax: QQ3095748324
Email: sales@run-biotech.com
Country: China
ProdList: 2402
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4943
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View Lastest Price from GW 3965 HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: GW 3965 HYDROCHLORIDE 405911-17-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 20tons
Release date: 2020-01-08

405911-17-3, GW 3965 HYDROCHLORIDERelated Search:

Trichlorofluoromethane Trifluoromethanesulfonyl chloride TRIFLUOROMETHYLSULPHENYL CHLORIDE Axitinib Carboplatin T0070907 PD 0325901 2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- Crizotinib 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE

3-[3-[n-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride

3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…

GW3965 HCl

2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride

GW3965 hydrochloride, >=98%

Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride

GW3965 HCl Salt

3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride

CS-742

GW 3965 HYDROCHLORIDE; GW-3965 HYDROCHLORIDE;

3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride

2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylet...

GW-3965 hydrochloride GW3965

Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride (1:1)

3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-Benzeneacetic acid hydrochloride (1:1)

W 3965 HYDROCHLORIDE

405911-17-3

C33H31F3ClNO3HCl

Inhibitors