ChemicalBook > CAS DataBase List > 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Product Name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
CAS No.
86393-33-1
Chemical Name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Synonyms
Q-ACID;Fluoroquinolonic acid;FLUOROQUINOLONE;7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID;AKOS 1131;Q.Acid levo;1-Ciprofloxacin;Ciprofloxacin -1;Fluorchinolonsure;TIMTEC-BB SBB003016
CBNumber
CB6111667
Molecular Formula
C13H9ClFNO3
Formula Weight
281.67
MOL File
86393-33-1.mol
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Property

Melting point:
242-245 °C(lit.)
Boiling point:
467.3±45.0 °C(Predicted)
Density 
1.652±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
6.36±0.41(Predicted)
form 
Solid
color 
Off-White to Light Yellow
InChIKey
ISPVACVJFUIDPD-UHFFFAOYSA-N
CAS DataBase Reference
86393-33-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-52/53
Safety Statements 
26-36-61-22
WGK Germany 
2
RTECS 
VB1993795
HazardClass 
IRRITANT
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1174
Product name
Fluoroquinolonic acid
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500mg
Price
$126
Updated
2024/03/01
Sigma-Aldrich
Product number
1278302
Product name
Fluoroquinolonic acid
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
150mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
C2293
Product name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$39
Updated
2024/03/01
TCI Chemical
Product number
C2293
Product name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
C2190050
Product name
Ciprofloxacin impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
c2190050
Price
$153
Updated
2024/03/01
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial

Uses

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.

General Description

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Suppliers

-Binhai Golden Hilen Medicine Chemistry Co., Ltd.
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0515-84383887 13777682051
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China
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View Lastest Price from 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 86393-33-1
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98.9%min
Supply Ability
20 TONS
Release date
2021-06-19
Guangzhou PI PI BIOTECH INC
Product
Ciprofloxacin Impurity A (EP) 86393-33-1
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-06-04
Henan Fengda Chemical Co., Ltd
Product
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4 86393-33-1
Price
US $8.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-29

86393-33-1, 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidRelated Search:


  • TIMTEC-BB SBB003016
  • 1-CYCLOPROPYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLONE-3-CARBOXYLIC ACID
  • 1-CYCLOPROPYL-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-3-QUINOLINIC CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUOROQUINOL-4-ONE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXYHYDROQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID
  • 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • AKOS 1131
  • 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-oxoquinoline-3-Carboxylate
  • 1-Ciprofloxacin
  • 7-CHLORO1-CYCLOPROPYL-6-FLUORO-1,4-DIHYD
  • FLUOROQUINOLONE
  • 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro 4-Oxoquinoline Carboxylic Acid
  • Chloro-1-cycloproyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinoline-3-carboxylicAcid
  • Fluoroquinolonic acid
  • FLUOROQUINOLONEACID
  • Fluorchinolonsure
  • 7-Chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic aci
  • 3-QUINOLINECARBOXYLICACID,7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO
  • 7-CHLORO-6-FLUORO-4-OXO-N-CYCLOPROPYL-1,4-DIHYDROQUINOLINE CARBOXYLIC ACID
  • Ciprofloxacin -1
  • 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylicaci
  • 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylicacid
  • Ciprofloxacin impurity A (EP)
  • 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinoline Carboxylic Acid (Q Acid)
  • Ciprofloxacin Impurity 1(Ciprofloxacin EP Impurity A)
  • Enrofloxacin Impurity 1(Enrofloxacin EP Impurity A)
  • 7-chloro-1-cyclopropyl-6-fluoro-4-oxo
  • Ciprofloxacin Hydrochloride Impurity Ⅰ:Ciprofloxacin EP Impurity A
  • Ciprofloxacin ImpuritⅠ:(Ciprofloxacin Impurity A)7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
  • Q.Acid levo
  • Q-ACID
  • Q-ACID, 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
  • Fluoroquinolonic acid, Q-Acid
  • 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid,98%
  • 7-Chloro-6-fluoro-1-cyclopropyl-1
  • 7-Chloro-6-fluoro-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acid(Q-acid )
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid,Fluoroquinolonic acid, Q-Acid
  • Fluoroquinolonic Acid (50 mg)
  • Fluoroquinolonic Acid (150 mg)
  • 1-Cyclopropyl-1,4-dihydro-4-oxo-6-fluoro-7-chloro-3-quinolinecarboxylic Acid
  • 7-Chloro-1-cyclopropyl-6-fluoro-3-carboxy-1,4-dihydro-4-oxoquinoline
  • Ciprofloxacin EP IMpurity A
  • Ciprofloxacin impurity A (PhEur)
  • Ciprofloxacin Related Compound A (USP)
  • 3-Carboxy-7-chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxoquinoline, (3-Carboxy-7-chloro-6-fluoro-4-oxoquinolin-1(4H)-yl)cyclopropane
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-0x0quinoline-3-carboxylic acid
  • 7-Chloro-1-CP-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid
  • Ciprofloxacin impurity A CRS
  • 7-Chloro-1-cyclopropyl-6-fluoro-4-o
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid &gt
  • Fluoroquinolonic acid A