Triciribine

Product Name: Triciribine
CAS No.: 61966-08-3
Chemical Name: Triciribine
Synonyms: TCN-P;PTX200;VQD 002;PTX 200;PTX-200;NSC-280594;VQD-002 (TCN-P);Sclareol Impurity 1;Tricirbine Phosphate;triciribine phosphate
CBNumber: CB61179989
Molecular Formula: C13H17N6O7P
Formula Weight: 400.286
MOL File: 61966-08-3.mol

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Triciribine Property

Density: 2.23
solubility: PBS (pH 7.2): 10 mg/ml
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T779400
Product name: Triciribinephosphate
Packaging: 10mg
Price: $395
Updated: 2021/12/16

Usbiological

Product number: 296526
Product name: Tricyclic nucleoside phosphate
Packaging: 5mg
Price: $460
Updated: 2021/12/16

TRC

Product number: T779400
Product name: Triciribinephosphate
Packaging: 25mg
Price: $920
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NT44794
Product name: Tricyclic nucleoside phosphate
Packaging: 5mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NT44794
Product name: Tricyclic nucleoside phosphate
Packaging: 10mg
Price: $395
Updated: 2021/12/16

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Triciribine Chemical Properties,Usage,Production

Uses

Triciribine phosphate is an Akt activation inhibitor that inhibits Akt phosphorylation by binding to the pleckstrin homology (PH) domain of the Akt and blocking its recruitment to the plasma membrane.

brand name

Triciribine is INN.

References

[1] N BERNDT. The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane[J]. Cell Death and Differentiation, 2010, 17 11: 1795-1804. DOI: 10.1038/cdd.2010.63
[2] PLAGEMANN P G. Transport, phosphorylation, and toxicity of a tricyclic nucleoside in cultured Novikoff rat hepatoma cells and other cell lines and relase of its monophosphate by the cells.[J]. JNCI Journal of the National Cancer Institute, 1976, 57 6: 1283-1295. DOI: 10.1093/jnci/57.6.1283
[3] B C BEHRENS. Activity of tricyclic nucleoside 5’-phosphate in model systems of human ovarian cancer.[J]. Investigational New Drugs, 1986, 4 4: 295-304. DOI: 10.1007/bf00173502
[4] ANTHONY R. PORCARI. Deoxy Sugar Analogues of Triciribine: Correlation of Antiviral and Antiproliferative Activity with Intracellular Phosphorylation[J]. Journal of Medicinal Chemistry, 2000, 43 12: 2438-2448. DOI: 10.1021/jm990205m

Triciribine Preparation Products And Raw materials

Raw materials

Preparation Products

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Triciribine Suppliers

China 34 France 1 India 1 United Kingdom 1 United States 4 Global 41

Jinan Trio PharmaTech Co., Ltd.

Tel: 0531-88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com
Country: China
ProdList: 1856
Advantage: 62

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
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China Kouting Group Limited

Tel: +86 (21) 5811-6473 5811-6475
Fax: +86 (21) 6129-4103
Email: sales@koutingchina.com
Country: China
ProdList: 496
Advantage: 60

shanghai cooperpharm co.,LTD .

Tel: +86-021-58975553
Fax: +86-021-58975554
Email: sales@cooperpharm.com
Country: China
ProdList: 1210
Advantage: 56

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
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Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
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Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
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Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
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61966-08-3, TriciribineRelated Search:

Clindamycin Clindamycin phosphate Sodium L-ascorbyl-2-phosphate API-2 7-DEAZA-2'-DEOXYADENOSINE DEAZAPURINE Triciribine TUBERCIDIN 4-Amino-7H-pyrrolo[2,3-d]pyrimidine N-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE

triciribine phosphate

1-(5-O-Phosphono-β-D-ribofuranosyl)-5-methyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylene-3-amine

1,5-Dihydro-5-methyl-1-(5-O-phosphono-β-D-ribofuranosyl)-1,4,5,6,8-pentaazaacenaphthylene-3-amine

NSC-280594

TCN-P

Triciribine 5'-phosphate

1,4,5,6,8-Pentaazaacenaphthylene-3-amino-1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl 5'-monophosphate

VQD 002

(1R,2S,3R,5R)-3-(3-aMino-5-Methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxyMethyl)cyclopentane-1,2-diol

VQD-002 (TCN-P)

Triciribine phosphate (NSC-280594)

URLYINUFLXOMHP-HTVVRFAVSA-N

Tricyclic Nucleoside Phosphate

Tricirbine Phosphate

1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-(5-O-phosphono-β-D-ribofuranosyl)-

Triciribine 13CD3 phosphate

PTX 200

PTX200

PTX-200

Triciribine phosphate (NSC-280594)/VQD-002,TCN-

Triciribine phosphate Sodium Salt

Sclareol Impurity 1

61966-08-3

C13H17N6O7P