7H-Pyrrolo[2,3-d]pyrimidine
- Product Name
- 7H-Pyrrolo[2,3-d]pyrimidine
- CAS No.
- 271-70-5
- Chemical Name
- 7H-Pyrrolo[2,3-d]pyrimidine
- Synonyms
- 7H-PYRROLO[2,3-D]PYRIMIDINE;7-Deazapurine;Pyrrolo[2,3-d]pyriMidine;3H-Pyrrolo[2,3-d]pyrimidine;NSC 94210;DEAZAPURINE;7-Deazapurine>1H-Pyrrolo[2,3-d]pyrimidine;1H-Pyrrolo[2,3-d]pyrimidi...;1H-Pyrrolo[2,3-d]pyrimidine (8CI,9CI)
- CBNumber
- CB9758502
- Molecular Formula
- C6H5N3
- Formula Weight
- 119.12
- MOL File
- 271-70-5.mol
7H-Pyrrolo[2,3-d]pyrimidine Property
- Melting point:
- 133℃
- Boiling point:
- 297.9±23.0 °C(Predicted)
- Density
- 1.38
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform, Dichloromethane, DMSO, Methanol
- form
- Powder
- pka
- 12.79±0.20(Predicted)
- color
- Orange
- λmax
- 270nm(MeOH)(lit.)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D4820
- Product name
- 7-Deazapurine
- Purity
- >98.0%(GC)(T)
- Packaging
- 200mg
- Price
- $46
- Updated
- 2025/07/31
- Product number
- D4820
- Product name
- 7-Deazapurine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $136
- Updated
- 2025/07/31
- Product number
- B529888
- Product name
- 7H-Pyrrolo[2,3-d]pyrimidine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 296394
- Product name
- 7H-Pyrrolo[2,3d]pyrimidine
- Packaging
- 250mg
- Price
- $358
- Updated
- 2021/12/16
- Product number
- D1810-40
- Product name
- 7-Deazapurine
- Packaging
- 100mg
- Price
- $418
- Updated
- 2021/12/16
7H-Pyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production
Uses
7H-Pyrrolo[2,3-d]pyrimidine is used as an organic synthesis or pharmaceutical intermediate. Its pyrrolo[2,3-d]pyrimidines are important parent heterocyclic compounds and are synthetic raw materials for the preparation of anti-rheumatoid arthritis and anti-tumour drugs.
Synthesis
3680-69-1
271-70-5
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine (compound 1001) (130 mg, 0.847 mmol) was used as a raw material and dissolved in 3 mL of methanol. The hydrogenation reaction was carried out by adding 10% Pd-C catalyst under hydrogen atmosphere at 1 atmosphere for 16 hours. Upon completion of the reaction, the reaction solution was concentrated to dryness to afford 7H-pyrrolo[2,3-d]pyrimidine (Compound 1002) in 100 mg yield and 98% yield. The product was characterized by 1H-NMR (CD3OD): δ 9.4 (s, 1H); 9.1 (s, 1H); 7.9 (s, 1H); 7.1 (s, 1H).
References
[1] Patent: WO2007/41130, 2007, A2. Location in patent: Page/Page column 40; Sheet 1/9
[2] Patent: US2008/9514, 2008, A1. Location in patent: Page/Page column 26-27
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 21, p. 5247 - 5250
[4] European Journal of Medicinal Chemistry, 2008, vol. 43, # 6, p. 1248 - 1260
[5] Patent: WO2012/2568, 2012, A1. Location in patent: Page/Page column 37
7H-Pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
7H-Pyrrolo[2,3-d]pyrimidine Suppliers
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View Lastest Price from 7H-Pyrrolo[2,3-d]pyrimidine manufacturers
- Product
- Baricitinib Impurity 92 271-70-5
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 99%+ HPLC
- Supply Ability
- 1000
- Release date
- 2025-07-02
- Product
- 7H-Pyrrolo[2,3-d]pyrimidine 271-70-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 7H-Pyrrolo[2,3-d]pyrimidine 271-70-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08