7H-Pyrrolo[2,3-d]pyrimidine

Product Name: 7H-Pyrrolo[2,3-d]pyrimidine
CAS No.: 271-70-5
Chemical Name: 7H-Pyrrolo[2,3-d]pyrimidine
Synonyms: 7H-PYRROLO[2,3-D]PYRIMIDINE;7-Deazapurine;Pyrrolo[2,3-d]pyriMidine;3H-Pyrrolo[2,3-d]pyrimidine;NSC 94210;DEAZAPURINE;7-Deazapurine>1H-Pyrrolo[2,3-d]pyrimidine;1H-Pyrrolo[2,3-d]pyrimidi...;1H-Pyrrolo[2,3-d]pyrimidine (8CI,9CI)
CBNumber: CB9758502
Molecular Formula: C6H5N3
Formula Weight: 119.12
MOL File: 271-70-5.mol

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7H-Pyrrolo[2,3-d]pyrimidine Property

Melting point:: 133℃
Boiling point:: 297.9±23.0 °C(Predicted)
Density: 1.38
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform, Dichloromethane, DMSO, Methanol
form: Powder
pka: 12.79±0.20(Predicted)
color: Orange
λmax: 270nm(MeOH)(lit.)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D4820
Product name: 7-Deazapurine
Purity: >98.0%(GC)(T)
Packaging: 200mg
Price: $46
Updated: 2025/07/31

TCI Chemical

Product number: D4820
Product name: 7-Deazapurine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $136
Updated: 2025/07/31

Usbiological

Product number: 296394
Product name: 7H-Pyrrolo[2,3d]pyrimidine
Packaging: 250mg
Price: $358
Updated: 2021/12/16

Usbiological

Product number: D1810-40
Product name: 7-Deazapurine
Packaging: 100mg
Price: $418
Updated: 2021/12/16

Usbiological

Product number: 295949
Product name: 7-Deazapurine
Packaging: 50mg
Price: $432
Updated: 2021/12/16

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7H-Pyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production

Uses

7H-Pyrrolo[2,3-d]pyrimidine is used as an organic synthesis or pharmaceutical intermediate. Its pyrrolo[2,3-d]pyrimidines are important parent heterocyclic compounds and are synthetic raw materials for the preparation of anti-rheumatoid arthritis and anti-tumour drugs.

Synthesis

3680-69-1

271-70-5

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine (compound 1001) (130 mg, 0.847 mmol) was used as a raw material and dissolved in 3 mL of methanol. The hydrogenation reaction was carried out by adding 10% Pd-C catalyst under hydrogen atmosphere at 1 atmosphere for 16 hours. Upon completion of the reaction, the reaction solution was concentrated to dryness to afford 7H-pyrrolo[2,3-d]pyrimidine (Compound 1002) in 100 mg yield and 98% yield. The product was characterized by 1H-NMR (CD3OD): δ 9.4 (s, 1H); 9.1 (s, 1H); 7.9 (s, 1H); 7.1 (s, 1H).

References

[1] Patent: WO2007/41130, 2007, A2. Location in patent: Page/Page column 40; Sheet 1/9
[2] Patent: US2008/9514, 2008, A1. Location in patent: Page/Page column 26-27
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 21, p. 5247 - 5250
[4] European Journal of Medicinal Chemistry, 2008, vol. 43, # 6, p. 1248 - 1260
[5] Patent: WO2012/2568, 2012, A1. Location in patent: Page/Page column 37

7H-Pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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7H-Pyrrolo[2,3-d]pyrimidine Suppliers

Americas 1 China 165 Europe 2 India 3 Japan 1 United Kingdom 2 United States 24 Global 198

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

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View Lastest Price from 7H-Pyrrolo[2,3-d]pyrimidine manufacturers

Moxin Chemicals

Product: Baricitinib Impurity 92 271-70-5
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 99%+ HPLC
Supply Ability: 1000
Release date: 2025-07-02

Zhuozhou Wenxi import and Export Co., Ltd

Product: 7H-Pyrrolo[2,3-d]pyrimidine 271-70-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 7H-Pyrrolo[2,3-d]pyrimidine 271-70-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

271-70-5, 7H-Pyrrolo[2,3-d]pyrimidineRelated Search:

Pyrrolo[2,3-d]pyrimidin-4-ol 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine 2,6-Dichloro-7-deazapurine 2,4-Dihydroxy-7-deazapurine 7H-pyrrolo[2,3-d]pyriMidine-5-carbaldehyde 4-(Hydroxyamino)-4-oxobutanoic acid N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Tofacitinib Impurity 29 N-Hydroxysuccinimide CYANOACETIC ACID-OSU 1-Benzyl-4-methyl-piperidin-3-one hydrochloride 6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE Benzyl chloride Malonyl chloride 4-Amino-2,6-dichloropyrimidine N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Tofacitinib Impurity 85 N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

7H-PYRROLO[2,3-D]PYRIMIDINE

DEAZAPURINE

1H-Pyrrolo[2,3-d]pyrimidine (8CI,9CI)

3H-Pyrrolo[2,3-d]pyrimidine

NSC 94210

1H-Pyrrolo[2,3-d]pyrimidine

7-Deazapurine

1H-Pyrrolo[2,3-d]pyrimidi...

Pyrrolo[2,3-d]pyriMidine

JR-13954, 7H-Pyrrolo[2,3-d]pyrimidine, 96%

7-Deazapurine&gt

7H-Pyrrolo[2,3-d]pyrimidine (6CI, 7CI, ACI)

4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-ol

271-70-5

PYRIMIDINE

Heterocycle-Pyrimidine series