2-Fluoro-5-(trifluoromethyl)aniline
- Product Name
- 2-Fluoro-5-(trifluoromethyl)aniline
- CAS No.
- 535-52-4
- Chemical Name
- 2-Fluoro-5-(trifluoromethyl)aniline
- Synonyms
- uoro-5-(trifL;α,α,α,6-Tetrafluoro-m-toluidine;3-AMINO-4-FLUOROBENZOTRIFLUORIDE;4-FLUORO-3-AMINOBENZOTRIFLUORIDE;3－amino－4－fluorobentozrifluoride;3-amino-4-fluoro bensotrifluoride;2-FLUORO-5-(TRIFLUOROMETHYL)ANILINE;3-Amino-4-fluorobenzotrifluoride97%;4-FLUORO-3-AMINOBENZOTRIFLUORIDE 97%;3-Amino-4-fluorobenzotrifluoride 97%
- CBNumber
- CB6123639
- Molecular Formula
- C7H5F4N
- Formula Weight
- 179.11
- MOL File
- 535-52-4.mol
2-Fluoro-5-(trifluoromethyl)aniline Property
- Boiling point:
- 155 °C (lit.)
- Density
- 1.378 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.461(lit.)
- Flash point:
- 158 °F
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform, Methanol
- pka
- 1.98±0.10(Predicted)
- form
- Oil
- color
- Clear Colourless
- Specific Gravity
- 1.378
- BRN
- 1950800
- InChI
- InChI=1S/C7H5F4N/c8-5-2-1-4(3-6(5)12)7(9,10)11/h1-3H,12H2
- InChIKey
- DRKWGMXFFCPZLW-UHFFFAOYSA-N
- SMILES
- C1(N)=CC(C(F)(F)F)=CC=C1F
- CAS DataBase Reference
- 535-52-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Alpha,alpha,alpha,6-tetrafluoro-m-toluidine(535-52-4)
Safety
- Hazard Codes
- Xn,Xi,T
- Risk Statements
- 20/21/22-36/37/38-23-21/22
- Safety Statements
- 26-36/37-45-36/37/39
- RIDADR
- UN2810/6.1/II
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- HS Code
- 29214200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 285056
- Product name
- 2-Fluoro-5-(trifluoromethyl)aniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $33.8
- Updated
- 2023/06/20
- Product number
- A1582
- Product name
- 3-Amino-4-fluorobenzotrifluoride
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $23
- Updated
- 2025/07/31
- Product number
- A1582
- Product name
- 3-Amino-4-fluorobenzotrifluoride
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $65
- Updated
- 2025/07/31
- Product number
- F596095
- Product name
- 2-Fluoro-5-(trifluoromethyl)aniline
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- F596095
- Product name
- 2-Fluoro-5-(trifluoromethyl)aniline
- Packaging
- 100g
- Price
- $360
- Updated
- 2021/12/16
2-Fluoro-5-(trifluoromethyl)aniline Chemical Properties,Usage,Production
Chemical Properties
clear yellow to orange liquid
Uses
2-Fluoro-5-(trifluoromethyl)aniline may be used in chemical synthesis studies.
Synthesis
367-86-2
7439-89-6
535-52-4
General procedure for the synthesis of 2-fluoro-5-trifluoromethylaniline from 2-nitro-4-trifluoromethylfluorobenzene and iron powder: Referring to Example 1, 2-fluoro-5-trifluoromethylaniline was prepared as follows: 20 g of 3-nitro-4-fluorobenzotrifluoride was dissolved in 50 mL of methanol. Under stirring conditions, 16 g of iron powder was slowly added and concentrated hydrochloric acid was added dropwise. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, an appropriate amount of sodium bicarbonate was added to neutralize the reaction solution. Subsequently, ether was added for extraction and the insoluble material was removed by filtration using diatomaceous earth. The ether phase was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 14 g of the target product 2-fluoro-5-trifluoromethylaniline in 82% yield.
References
[1] Patent: EP1243584, 2002, A1
2-Fluoro-5-(trifluoromethyl)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Fluoro-5-(trifluoromethyl)aniline manufacturers
- Product
- 2-Fluoro-5-(trifluoromethyl)aniline 535-52-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-01
- Product
- 2-Fluoro-5-(trifluoromethyl)aniline 535-52-4
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000000
- Release date
- 2024-08-15
- Product
- 2-Fluoro-5-(trifluoromethyl)aniline 535-52-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000
- Release date
- 2025-04-01