Brand Name(s) in US
ChemicalBook > CAS DataBase List > Marbofloxacin

Marbofloxacin

Brand Name(s) in US
Product Name
Marbofloxacin
CAS No.
115550-35-1
Chemical Name
Marbofloxacin
Synonyms
Marbofloxacine;9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid;CS-939;zeniquin;Marbocyl;ZENIQUIN(R);Ma Bo effect;MARBOFLOXACIN;Marboflaxacine;Marbofloxacin>
CBNumber
CB6125860
Molecular Formula
C17H19FN4O4
Formula Weight
362.36
MOL File
115550-35-1.mol
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Marbofloxacin Property

Melting point:
268-269°C (dec.)
Boiling point:
571℃
Density 
1.55±0.1 g/cm3(Predicted)
Flash point:
>110°(230°F)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly, Heated)
pka
6.02±0.20(Predicted)
color 
Light Yellow
Water Solubility 
Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml
Merck 
14,5750
InChI
InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
InChIKey
BPFYOAJNDMUVBL-UHFFFAOYSA-N
SMILES
N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C
CAS DataBase Reference
115550-35-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
52/53-36/37/38
Safety Statements 
61-36-26-60
WGK Germany 
2
RTECS 
UU8815140
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000819
Product name
Marbofloxacin
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000819
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
34039
Product name
Marbofloxacin
Purity
VETRANAL?, analytical standard
Packaging
100MG
Price
$137
Updated
2024/03/01
TCI Chemical
Product number
M2240
Product name
Marbofloxacin
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$158
Updated
2024/03/01
TCI Chemical
Product number
M2240
Product name
Marbofloxacin
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$466
Updated
2024/03/01
Alfa Aesar
Product number
J66407
Product name
Marbofloxacin, 99.7%
Packaging
50mg
Price
$131
Updated
2021/12/16
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Marbofloxacin Chemical Properties,Usage,Production

Brand Name(s) in US

Zeniquin, Marbocyl

Description

Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.

Chemical Properties

Crystalline Solid

Uses

Fluorinated quinolone antibacterial

Uses

A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species

Application

Marbofloxacin is an FDA-approved broad-spectrum bactericidal fluoroquinolone available in oral tablet and injectable forms. It has been shown to have varying therapeutic effects in a wide range of animal diseases in dogs, cats, horses, cattle and pigs. It can be used to treat skin and soft tissue infections in dogs and cats, urinary tract infections in dogs, some blood borne pathogens (e.g. Mycoplasma haematobium) in cats, equine infections caused by susceptible bacteria, bovine respiratory disease, and porcine respiratory disease pathogens.

Definition

ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.

Side effects

The most common side effects of Marbofloxacin are vomiting, diarrhoea and loss of appetite. More serious side effects include cartilage abnormalities (which may cause difficulty walking), prolonged loss of appetite, incoordination, convulsions, depression, fever, rash, or difficulty breathing. Blindness and eye damage in cats has been a concern at high doses.

Veterinary Drugs and Treatments

Marbofloxacin is labeled for the treatment of susceptible bacterial infections in dogs and cats.

Marbofloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Marbofloxacin manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.
Product
Marbofloxacin 115550-35-1
Price
US $0.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
10tons
Release date
2024-04-25
Hebei Guanlang Biotechnology Co., Ltd.
Product
Marbofloxacin 115550-35-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-07-02
Zibo Wei Bin Import & Export Trade Co. Ltd.
Product
Marbofloxacin 115550-35-1
Price
US $100.00/kg
Min. Order
1kg
Purity
99
Supply Ability
10t
Release date
2023-07-06

115550-35-1, MarbofloxacinRelated Search:


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  • Marbofloxacin EP/BP
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  • 11550-35-1
  • C17H19FN4O4
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  • 115550-35-1