ChemicalBook > CAS DataBase List > cannabisin F

cannabisin F

Product Name
cannabisin F
CAS No.
163136-19-4
Chemical Name
cannabisin F
Synonyms
cannabisin F;2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-[4-[(1E)-3-[[2-(4-hydroxyphenyl)ethyl]amino]-3-oxo-1-propen-1-yl]-2-methoxyphenoxy]-, (2Z)-
CBNumber
CB61315466
Molecular Formula
C36H36N2O8
Formula Weight
624.68
MOL File
163136-19-4.mol
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cannabisin F Property

Boiling point:
961.0±65.0 °C(Predicted)
Density 
1.295±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
9.78±0.31(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN97809
Product name
CannabisinF
Purity
≥98%
Packaging
5mg
Price
$643
Updated
2021/12/16
Crysdot
Product number
CD32002267
Product name
CannabisinF
Purity
95+%
Packaging
5mg
Price
$998
Updated
2021/12/16
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cannabisin F Chemical Properties,Usage,Production

Biological Activity

Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2[1]. Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1[1].Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1[1].

target

Immunology & Inflammation related

References

[1]. Wang S, et al. Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator. Int J Mol Sci. 2019;20(3):507. Published 2019 Jan 25.

cannabisin F Preparation Products And Raw materials

Raw materials

Preparation Products

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163136-19-4, cannabisin FRelated Search:

Hydroxyecdysone alpha-Cyperone alpha-Terpineol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol MOSLOFLAVONE hydroxygenkwanin beta-Eudesmol 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one CANNABIDIOL cannabisin E Cannabisin D N,N'-Bis[2-(4-hydroxyphenyl)ethyl]-6,7-dihydroxy-1-(3,4-dihydroxyphenyl)naphthalene-2,3-dicarboxamide cannabisin G

  • cannabisin F
  • 2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-[4-[(1E)-3-[[2-(4-hydroxyphenyl)ethyl]amino]-3-oxo-1-propen-1-yl]-2-methoxyphenoxy]-, (2Z)-
  • 163136-19-4
  • C36H36N2O8