Dextromethorphan hydrobromide monohydrate

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Dextromethorphan hydrobromide monohydrate

Product Name: Dextromethorphan hydrobromide monohydrate
CAS No.: 6700-34-1
Chemical Name: Dextromethorphan hydrobromide monohydrate
Synonyms: Dextromethorphan HBr monohydrate;DextroMethorphan hydrobroMide hydrate;dextromethorphansigmareference*standard;Dextromethorphan Hydrobromide dextrorotation;(9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN HYDROBROMIDE, D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE MONOHYDRATE;DMHM;Dextromethorphan hyd;DEXTROMETHORPHAN HBr IP;Morphinan,3-methoxy-17-methyl-;Dextromethorphani Hydrobromidum
CBNumber: CB6131946
Molecular Formula: C18H28BrNO2
Formula Weight: 370.33
MOL File: 6700-34-1.mol

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Dextromethorphan hydrobromide monohydrate Property

Melting point:: 116-119°C
alpha: [α]D25 +26～+30° (c=1.85, H2O)
Flash point:: 11 °C
storage temp.: Store at RT
solubility: Sparingly soluble in water, freely soluble in ethanol (96 per cent).
form: solid
color: White to Off-White
PH: pH (10g/l, 25℃) : 5.2～6.5
BRN: 6453793
InChIKey: QYPSYPPSHXDFLV-UHFFFAOYSA-N
LogP: 1.351 (est)
CAS DataBase Reference: 6700-34-1(CAS DataBase Reference)

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45
WGK Germany: 3
HS Code: 3822000002

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D2531
Product name: Dextromethorphan hydrobromide monohydrate
Purity: ≥99% (TLC)
Packaging: 5g
Price: $80.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: D0740000
Product name: Dextromethorphan hydrobromide
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: D0740000
Price: $168
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1181007
Product name: Dextromethorphan hydrobromide
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 500mg
Price: $436
Updated: 2024/03/01

Cayman Chemical

Product number: 13950
Product name: Dextromethorphan (hydrobromide hydrate)
Purity: ≥98%
Packaging: 50mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 13950
Product name: Dextromethorphan (hydrobromide hydrate)
Purity: ≥98%
Packaging: 100mg
Price: $61
Updated: 2024/03/01

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Dextromethorphan hydrobromide monohydrate Chemical Properties,Usage,Production

Description

Dextromethorphan (DXM) is a dextratrorotatory morphinan with structural similarity to levorphanol, codeine, and morphine. Because of its strong antitussive effects, dextromethorphan is widely used as a cough suppressant. However, it does not provoke opioid activity as is characteristic of several other morphine derivatives. DXM binds to and inhibits NMDA (IC₅₀ = 0.55 μM) and nicotinic receptors (IC₅₀s = 0.7-3.9 μM) and blocks receptor-gated and voltage-gated calcium channels (IC₅₀ = 60 μM) and voltage-gated sodium channels (IC₅₀ = 78 μM). DXM has been used in multimodal analgesic therapies for acute and neuropathic pain.

Chemical Properties

White Solid

Uses

Antitussive;Opioid ligand

Uses

An antitussive drug. Orally active synthetic morphine analog. Analgesic (narcotic). Racemethorphan and levomethorpham are controlled substances (opiates).

Definition

ChEBI: Dextromethorphan hydrobromide is the hydrobromide and monohydrate of the antitussive drug dextromethorphan. It is a hydrate and a hydrobromide. It contains a dextromethorphan.

brand name

Benylin DM (Parke-Davis); Dextromethorphan Hydrobromide OROS Tablets (Ciba-Geigy); Drixoral Cough (Schering-Plough HealthCare); PediaCare 1 (McNeil Consumer); Romilar (Hoffmann-LaRoche-International); St. Joseph Cough Syrup (Schering-Plough HealthCare).

Biological Activity

Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.

Toxics Screening Level

The Initial Threshold Screening Level (ITSL) is 0.4 μg/m3 annual average.

Dextromethorphan hydrobromide monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dextromethorphan hydrobromide monohydrate manufacturers

Shandong Hanjiang Chemical Co., Ltd

Product: Dextromethorphan hydrobromide monohydrate 6700-34-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10T
Release date: 2024-01-25

Anhui Yisheng Technology Co., LTD

Product: Dextromethorphan Hydrobromide Monohydrate 6700-34-1
Price: US $50.00-45.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 2 Ton
Release date: 2023-01-10

Wuhan Han Sheng New Material Technology Co.，Ltd

Product: Dextromethorphan Hydrobromide 6700-34-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.54%
Supply Ability: 20tons
Release date: 2023-04-19

6700-34-1, Dextromethorphan hydrobromide monohydrateRelated Search:

MELIBIOSE Dextromethorphan D-Glucose monohydrate Citric acid monohydrate 3-Isobutyl-1H-pyrazole-5-carboxylic acid 1,4,5,6-TETRAHYDRO-CYCLOPENTAPYRAZOLE-3-CARBOXYLIC ACID Ethyl 3-n-propylpyrazole-5-carboxylate 1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 3-CYCLOPROPYLPYRAZOLE-5-CARBOXYLIC ACID 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID Dextromethorphan Hydrobromide INDAZOLE-3-CARBOXYLIC ACID Hydrogen bromide 4,5,6,7-TETRAHYDRO-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER 1H-Pyrazole-3-carboxylicacid,1-methyl-5-propyl-,ethylester(9CI) 2-METHYL-4,5,6,7-TETRAHYDRO-2H-INDAZOLE-3-CARBOXYLIC ACID 4,5,6,7,8,9-HEXAHYDRO-1H-CYCLOOCTAPYRAZOLE-3-CARBOXYLIC ACID 1H-Pyrazole-3-carboxylicacid,1-methyl-5-propyl-(9CI)

Dextromethorphan Hydrobromide dextrorotation

dextromethorphansigmareference*standard

DMHM

(9α,13α,14α)-3-Methoxy-17-MethylMorphinan HydrobroMide Hydrate

3-Methoxy-17-Methyl-9α,13α,14α-Morphinan HydrobroMide Hydrate

d-3-Methoxy-N-MethylMorphinan HydrobroMide Monohydrate

DextroMethorphan hydrobroMide:Monohydrat

DextroMethorphan hydrobroMide hydrate

Morphinan,3-Methoxy-17-Methyl-, hydrobroMide, hydrate (1:1:1), (9a,13a,14a)-

(9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN HYDROBROMIDE, D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE MONOHYDRATE

Morphinan,3-methoxy-17-methyl-

D-3-METHOXY-N-METHYLMORPHINAN HYDROBROMIDE

DEXTROMETHORPHAN HYDROBROMIDE MONOHYDRATE

DEXTROMETHORPHAN HYDROBROMIDE, PH EUR

DEXTROMETHORPHAN HYDROBROMIDE*MONOHYDRAT E USP

D-Methorphan hydrobromide monohydrate

Morphinan, 3-methoxy-17-methyl-, hydrobromide, monohydrate, (9.alpha.,13.alpha.,14.alpha.)-

Dextromethorphan hydrobromicum, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide

Dextromethorphan monohydrate hydrobromide

Dextromethorphan monohydrate hydrobromide, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide

(9α,13α,14α)-3-Methoxy-17-methylmorphinanhydrobromide

Dextromethorphan hydrobromide monohydrate,(9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide, Dextromethorphan hydrobromicum

Dextromethorphan hydrobromide monohydrate,(9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide, d-3-Methoxy-N-methylmorphinan hydrobromide monohydrate, Dextromethorphan hydrobromide monohydrate

Dextromethorphan Hydrobromide (500 mg) Certified Reference Material (CRM)

Dextromethorphan Hydrobromide (500 mg)

Dextromethorphan hyd

DextroMethorphan HydrobroMide (Certified Reference Material (CRM))

Dextromethorphan HBr monohydrate

DextroMethorphan HydrobroMide, Monohydrate, USP, EP

(+)-3-Methoxy-N-MethylMorphinan HydrobroMide Monohydrate

Dextromethorphani Hydrobromidum

High quality pure dextromethorphan hydrochloride powder

Dextromethorphan hydrobromide monohydrate USP/EP/BP

Dextromethorphan Hydrobromide MonohydrateQ: What is Dextromethorphan Hydrobromide Monohydrate Q: What is the CAS Number of Dextromethorphan Hydrobromide Monohydrate Q: What is the storage condition of Dextromethorphan Hydrobromide Monohydrate Q: What are the applications of Dextromethorphan Hydrobromide Monohydrate

Dextromethorphan Hydrobromide (1181007)

Pharmaceutical Dextromethorphan Hydrobromide Monohydrate

DEXTROMETHORPHAN HBr IP

(4bS,8aS,9S)-3-methoxy-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene hydrobromide hydrate

Dexmesophane hydrobromide monohydrate

Dextromethorphan hydrobromide monohydratec

6700-34-1

C18H28BrNO2

C18H25NOHBrH2O

37032

C18H30BrNO3

Allosteric antagonist at NMDA-controlled ion channels; antagonist at voltage-dependent channels

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