3-Fluoro-4-methoxybenzonitrile

Product Name: 3-Fluoro-4-methoxybenzonitrile
CAS No.: 331-62-4
Chemical Name: 3-Fluoro-4-methoxybenzonitrile
Synonyms: 4-Cyano-2-fluoroanisole;Phenyl Acetate Impurity 22;Fluoromethoxybenzonitrile5;3-FLUORO-4-METHOXYBENZONITRILE;3-fluoro-4-methoxy-carbonitrile;Benzonitrile, 3-fluoro-4-methoxy-;3-Fluoro-4-methoxybenzonitrile>3-Fluoro-4-methoxybenzonitrile98%;3-Fluoro-4-methoxybenzonitrile 98%;4-FLUORO-3-METHOXYBENZONITRILE, 98+%
CBNumber: CB6132170
Molecular Formula: C8H6FNO
Formula Weight: 151.14
MOL File: 331-62-4.mol

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3-Fluoro-4-methoxybenzonitrile Property

Melting point:: 97-101 °C
Boiling point:: 96-98°C/1mm
Density: 1.18±0.1 g/cm3(Predicted)
Flash point:: 96-98°C/1mm
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
color: White to Almost white
InChIKey: FEEOVAOEPGQDTJ-UHFFFAOYSA-N
CAS DataBase Reference: 331-62-4(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 23-36/37/39-36-26
RIDADR: 3439
WGK Germany: 3
Hazard Note: Toxic
HazardClass: 6.1
PackingGroup: III
HS Code: 29269090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 675822
Product name: 3-Fluoro-4-methoxybenzonitrile
Purity: 97%
Packaging: 5g
Price: $57.8
Updated: 2023/06/20

TCI Chemical

Product number: F0671
Product name: 3-Fluoro-4-methoxybenzonitrile
Purity: >98.0%(GC)
Packaging: 1g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: F0671
Product name: 3-Fluoro-4-methoxybenzonitrile
Purity: >98.0%(GC)
Packaging: 5g
Price: $103
Updated: 2025/07/31

TRC

Product number: F596158
Product name: 3-Fluoro-4-methoxybenzonitrile
Packaging: 5g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4637-3-34
Product name: 3-Fluoro-4-methoxybenzonitrile
Purity: 98%
Packaging: 5G
Price: $24
Updated: 2021/12/16

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3-Fluoro-4-methoxybenzonitrile Chemical Properties,Usage,Production

Chemical Properties

Colorless solid

Synthesis

2357-52-0

331-62-4

General procedure for the synthesis of 3-fluoro-4-methoxybenzonitrile from 2-fluoro-4-bromoanisole: 20 g of 2-fluoro-4-bromoanisole and 9.8 g of copper cyanide were dissolved in 100 mL of dimethylformamide, and the reaction was carried out at reflux with heat for 10 hours. Upon completion of the reaction, an aqueous solution of 20 g of ferric chloride dissolved in 100 mL of water was added to the reaction mixture. The reaction mixture was cooled to room temperature and the target product was extracted with toluene. The organic layer was washed sequentially with water, saturated aqueous sodium carbonate solution and saturated aqueous table salt solution. After separation of the organic layer, the extract was dried with anhydrous sodium sulfate, followed by distillation to remove the solvent. The crude product was purified by silica gel column chromatography (unfolding reagent ratio hexane:ethyl acetate=10:1) and further recrystallized with ethanol. Finally 10.0 g of 3-fluoro-4-methoxybenzonitrile was obtained in 68% yield.

References

[1] Patent: US4997942, 1991, A

3-Fluoro-4-methoxybenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Fluoro-4-methoxybenzonitrile Suppliers

Americas 1 China 129 Europe 3 France 1 Germany 4 India 7 Italy 1 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 22 United States 32 Global 203

J & K SCIENTIFIC LTD.

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View Lastest Price from 3-Fluoro-4-methoxybenzonitrile manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Fluoro-4-methoxybenzonitrile 331-62-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20t
Release date: 2024-05-23

Honest Joy Holdings Limited

Product: 3-Fluoro-4-methoxybenzonitrile 331-62-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.3%
Supply Ability: 100 tons
Release date: 2022-02-18

Hebei shuoxi biotechnology co. LTD

Product: 3-Fluoro-4-methoxybenzonitrile 331-62-4
Price: US $0.00/KG
Min. Order: 1g
Purity: 99.9%
Supply Ability: 1 ton
Release date: 2019-10-24

331-62-4, 3-Fluoro-4-methoxybenzonitrileRelated Search:

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3-FLUORO-4-METHOXYBENZONITRILE

Fluoromethoxybenzonitrile5

3-Fluoro-4-methoxybenzonitrile 98%

3-Fluoro-4-methoxybenzonitrile98%

3-fluoro-4-methoxy-carbonitrile

4-FLUORO-3-METHOXYBENZONITRILE, 98+%

4-Cyano-2-fluoroanisole

3-Fluoro-4-methoxybenzonitrile&gt

Benzonitrile, 3-fluoro-4-methoxy-

Phenyl Acetate Impurity 22

331-62-4

Anisoles, Alkyloxy Compounds & Phenylacetates

Fluorine Compounds

Nitriles

C8 to C9

Cyanides/Nitriles

Nitrogen Compounds

blocks

Carboxes

FluoroCompounds

Aromatic Nitriles