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4-CHLORO-2-PHENYLQUINAZOLINE

Product Name
4-CHLORO-2-PHENYLQUINAZOLINE
CAS No.
6484-25-9
Chemical Name
4-CHLORO-2-PHENYLQUINAZOLINE
Synonyms
AM-ex-OL;AKOS 93518;NSC 400965;am-ex-ol tm;AM-EX-OL(R);AM-ex-OL®4-Chloro-2-phenyl-quizoline;2-Phenyl-4-chloroquinazoline;4-CHLORO-2-PHENYLQUINAZOLINE;QUINAZOLINE, 4-CHLORO-2-PHENYL-
CBNumber
CB6137584
Molecular Formula
C14H9ClN2
Formula Weight
240.69
MOL File
6484-25-9.mol
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4-CHLORO-2-PHENYLQUINAZOLINE Property

Melting point:
124-126 °C(lit.)
Boiling point:
383.11°C (rough estimate)
Density 
1.285
refractive index 
1.5749 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Crystalline Powder
pka
0.67±0.30(Predicted)
color 
Slightly yellow to yellow
InChIKey
OBHKONRNYCDRKM-UHFFFAOYSA-N
CAS DataBase Reference
6484-25-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
162434
Product name
4-Chloro-2-phenylquinazoline
Purity
97%
Packaging
5g
Price
$62.4
Updated
2023/01/07
AK Scientific
Product number
J55066
Product name
4-Chloro-2-phenylquinazoline
Packaging
5g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
J55066
Product name
4-Chloro-2-phenylquinazoline
Packaging
1g
Price
$20
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC50857
Product name
4-Chloro-2-phenylquinazoline
Packaging
5G
Price
$100
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0023396
Product name
4-CHLORO-2-PHENYLQUINAZOLINE
Purity
95.00%
Packaging
1G
Price
$128.1
Updated
2021/12/16
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4-CHLORO-2-PHENYLQUINAZOLINE Chemical Properties,Usage,Production

Chemical Properties

slightly yellow to yellow crystalline powder

Uses

Reactant involved in the synthesis of biologically active molecules including:

  • Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity
  • Quinazoline-containing piperazinylpyrimidine derivatives with antitumor activity
  • Quinazoline substituted cyclopentane as HCV NS3/4A protease inhibitors
  • Quinazolines with antibacterial and antitumor activity
  • Aurora inhibitor MK-0457

Reactant involved in Suzuki-Miyaura cross-coupling and catalyst-free / base-free water promoted nucleophilic aromatic substitution

Uses

4-Chloro-2-phenylquinazoline can be involved in the synthesis of biologically active molecules including: Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1299, 1946 DOI: 10.1021/ja01211a055

4-CHLORO-2-PHENYLQUINAZOLINE Preparation Products And Raw materials

Raw materials

2-Bromobenzoic acid Copper N,N-Dimethylformamide Potassium carbonate Phosphorus oxychloride Benzamidine hydrochloride Methanol

Preparation Products

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4-CHLORO-2-PHENYLQUINAZOLINE Suppliers

Belgium 1 China 85 Germany 2 India 1 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 4 United States 16 Global 112
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View Lastest Price from 4-CHLORO-2-PHENYLQUINAZOLINE manufacturers

Changzhou waston chemical technology Co.,Ltd
Product
4-CHLORO-2-PHENYLQUINAZOLINE 6484-25-9
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
According to customer requirements
Release date
2022-10-19
Career Henan Chemical Co
Product
4-CHLORO-2-PHENYLQUINAZOLINE 6484-25-9
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-10

6484-25-9, 4-CHLORO-2-PHENYLQUINAZOLINERelated Search:

4-CHLORO-2-PHENYLQUINAZOLINE Oxazoline Quinazoline 4-CHLORO-2-(2-FLUORO-PHENYL)-QUINAZOLINE 2-(4-BROMO-PHENYL)-4-CHLORO-QUINAZOLINE QUINAZOLINE, 4-CHLORO-7-FLUORO-2-PHENYL- 4-CHLORO-2-(4-METHOXY-PHENYL)-QUINAZOLINE 4-CHLORO-2-(4-CHLORO-PHENYL)-QUINAZOLINE 4,6-DICHLORO-2-PHENYL-QUINAZOLINE 6-BROMO-4-CHLORO-2-PHENYL-QUINAZOLINE 4-chloro-2-(2-chlorophenyl)quinazoline QUINAZOLINE, 4-CHLORO-6-FLUORO-2-PHENYL- 4-CHLORO-2-(4-FLUORO-PHENYL)-QUINAZOLINE 4,7-DICHLORO-2-PHENYL-QUINAZOLINE 6-chloro-4-phenylquinazoline 6-BROMO-2-CHLORO-4-PHENYLQUINAZOLINE 4-CHLORO-2-(3-CHLORO-PHENYL)-QUINAZOLINE AURORA 19333

  • AKOS 93518
  • AM-EX-OL(R)
  • 4-CHLORO-2-PHENYLQUINAZOLINE
  • QUINAZOLINE, 4-CHLORO-2-PHENYL-
  • 4-CHLORO-2-PHENYLQUINAZOLINE OR AM-ex-OL
  • AM-EX-OL, 97% (4-CHLORO-2-PHENYL-QUINAZO LINE)
  • am-ex-ol tm
  • 4-CHLORO-2-PHENYLQUINAZOLINE 97%
  • 4-CHLORO-2-PHENYLQUINAZOLINE HPLC 99+%
  • 2-Phenyl-4-chloroquinazoline
  • 4-Chloro-2-phenylquinazoline,97%
  • AM-ex-OL
  • 4-Chloro-2-phenylquinazoline, 97% 5GR
  • NSC 400965
  • AM-EX-OL, (4-CHLORO-2-PHENYL-QUINAZO LINE)
  • 4-Chloro-2-phenyl-quizoline
  • AM-ex-OL&reg
  • 4-Chloro-2-phenylquinazoline?New
  • 6484-25-9
  • C14H9ClN2
  • HETERO CHLORIDE
  • Quinazolines
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Building Blocks
  • quinazoline
  • Building Blocks
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Quinazolines