Albiglutide

ChemicalBook > CAS DataBase List > Albiglutide

Product Name: Albiglutide
CAS No.: 782500-75-8
Chemical Name: Albiglutide
Synonyms: Albugon;Gsk 716155;albiglutide;Naliglutide;Unii-5E7U48495e;Albiglutide Fragment;Albiglutide（Acetate）;Albiglutide USP/EP/BP;7-36-Glucagon-like peptide I (8-glycine) (human), fusion protein with 7-36-glucagon-like peptide I (8-glycine) (human) fusion protein with serum;7-36-Glucagon-likepeptide I [8-glycine] (huMan), fusion protein with 7-36-glucagon-like peptide I[8-glycine] (huMan) fusion protein with seruM albuMin (huMan)
CBNumber: CB61518490
Molecular Formula: C148H223N39O46
Formula Weight: 3284.58792
MOL File: 782500-75-8.mol

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Albiglutide Property

storage temp.: Store at -20°C
Water Solubility: Water: 100 mg/mL (30.45 mM);
InChIKey: OGWAVGNOAMXIIM-VTAHJYCESA-N

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Safety

Hazardous Substances Data: 782500-75-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0024526
Product name: ALBIGLUTIDE
Purity: 95.00%
Packaging: 5MG
Price: $502.4
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573360
Product name: Albiglutide
Purity: >98%
Packaging: 100mg
Price: $1431.4
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573360
Product name: Albiglutide
Purity: >98%
Packaging: 250mg
Price: $2839
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573360
Product name: Albiglutide
Purity: >98%
Packaging: 1g
Price: $5654.2
Updated: 2021/12/16

DC Chemicals

Product number: DC20174
Product name: Albiglutide
Purity: >98%
Packaging: 1g
Price: $3800
Updated: 2021/12/16

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Albiglutide Chemical Properties,Usage,Production

General Description

Albiglutide (also known as naliglutide, GSK 716155) isa sequential dimer of GLP-1(7–36)(Ala8→Gly) covalentlylinked to modified human serum albumin (i.e., it is a “fusionprotein” with modified HSA). This molecule is currentlywell into phase III clinical trials. Although albiglutide,if marketed (Syncria, GlaxoSmithKline), will—likeexenatide—be administered by injection, the half-life andduration of 6 to 7 days would allow for weekly administration.

Clinical Use

GLP-1 receptor agonist:
Treatment of type 2 diabetes mellitus

Enzyme inhibitor

This GLP-1 agonist and anti-diabetic drug (MW = 72.9 kDa; CAS 782500- 75-8), marketed as Eperzan? and Tanzeum?, by GlaxoSmithKline (GSK) is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide has a half-life of 4-7 days, commending it for biweekly or weekly administration in the treatment of Type 2 diabetes. The half-life is considerably longer than exenatide (Byetta?) and liraglutide (Victoza?).

Metabolism

Albiglutide is a protein for which the expected metabolic pathway is degradation to small peptides and individual amino acids by ubiquitous proteolytic enzymes.

Albiglutide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Albiglutide manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Albiglutide 782500-75-8
Price: US $95.00-950.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-27

Nantong Guangyuan Chemicl Co,Ltd

Product: Albiglutide 782500-75-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-10-12

Henan Tengmao Chemical Technology Co. LTD

Product: Albiglutide 782500-75-8
Price: US $220.00-210.00/kilograms
Min. Order: 1kilograms
Purity: 99%
Supply Ability: 500tons
Release date: 2023-11-09

782500-75-8, AlbiglutideRelated Search:

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albiglutide

Albugon

Naliglutide

7-36-Glucagon-like peptide I (8-glycine) (human), fusion protein with 7-36-glucagon-like peptide I (8-glycine) (human) fusion protein with serum

Gsk 716155

Unii-5E7U48495e

7-36-Glucagon-likepeptide I [8-glycine] (huMan), fusion protein with 7-36-glucagon-like peptide I[8-glycine] (huMan) fusion protein with seruM albuMin (huMan)

Albiglutide Fragment

Albiglutide USP/EP/BP

Albiglutide（Acetate）

782500-75-8

GLP