ChemicalBook > CAS DataBase List > Albiglutide
Albiglutide
- Product Name
- Albiglutide
- CAS No.
- 782500-75-8
- Chemical Name
- Albiglutide
- Synonyms
- Albugon;Gsk 716155;albiglutide;Naliglutide;Unii-5E7U48495e;Albiglutide Fragment;Albiglutide（Acetate）;Albiglutide USP/EP/BP;Research Grade Albiglutide;Albiglutide Eperzan Tanzeum
- CBNumber
- CB61518490
- Molecular Formula
- C148H223N39O46
- Formula Weight
- 3284.58792
- MOL File
- 782500-75-8.mol
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Albiglutide Property
- storage temp.
- Store at -20°C
- Water Solubility
- Water: 100 mg/mL (30.45 mM);
- InChIKey
- OGWAVGNOAMXIIM-VTAHJYCESA-N
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Safety
- Hazardous Substances Data
- 782500-75-8(Hazardous Substances Data)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0024526
- Product name
- ALBIGLUTIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.4
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573360
- Product name
- Albiglutide
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1431.4
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573360
- Product name
- Albiglutide
- Purity
- >98%
- Packaging
- 250mg
- Price
- $2839
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573360
- Product name
- Albiglutide
- Purity
- >98%
- Packaging
- 1g
- Price
- $5654.2
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC20174
- Product name
- Albiglutide
- Purity
- >98%
- Packaging
- 1g
- Price
- $3800
- Updated
- 2021/12/16
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Albiglutide Chemical Properties,Usage,Production
General Description
Albiglutide (also known as naliglutide, GSK 716155) isa sequential dimer of GLP-1(7–36)(Ala8→Gly) covalentlylinked to modified human serum albumin (i.e., it is a “fusionprotein” with modified HSA). This molecule is currentlywell into phase III clinical trials. Although albiglutide,if marketed (Syncria, GlaxoSmithKline), will—likeexenatide—be administered by injection, the half-life andduration of 6 to 7 days would allow for weekly administration.
Clinical Use
GLP-1 receptor agonist:
Treatment of type 2 diabetes mellitus
Enzyme inhibitor
This GLP-1 agonist and anti-diabetic drug (MW = 72.9 kDa; CAS 782500- 75-8), marketed as Eperzan? and Tanzeum?, by GlaxoSmithKline (GSK) is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide has a half-life of 4-7 days, commending it for biweekly or weekly administration in the treatment of Type 2 diabetes. The half-life is considerably longer than exenatide (Byetta?) and liraglutide (Victoza?).
Metabolism
Albiglutide is a protein for which the expected metabolic pathway is degradation to small peptides and individual amino acids by ubiquitous proteolytic enzymes.
Albiglutide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Albiglutide manufacturers
Shandong Huizhihan Supply Chain Co., Ltd
- Product
- Albiglutide Eperzan Tanzeum 782500-75-8
- Price
- US $0.00-0.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 2000
- Release date
- 2024-10-30
Shandong Huizhihan Supply Chain Co., Ltd
- Product
- Albiglutide GLP-1 Naliglutide 782500-75-8
- Price
- US $0.00-0.00/BOX
- Min. Order
- 1BOX
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-11-12
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Albiglutide 782500-75-8
- Price
- US $0.00/mg
- Min. Order
- 1mg
- Purity
- ≥95% or 98%
- Supply Ability
- 1kg/month
- Release date
- 2021-06-23
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