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2-Fluorophenylacetone

Product Name
2-Fluorophenylacetone
CAS No.
2836-82-0
Chemical Name
2-Fluorophenylacetone
Synonyms
2-FLUOROPHENYLACETONE;o-Fluorophenylacetone;2-Fluorophenylacetone99%;2-Fluorophenylacetone 99%;1-(2-Fluorophenyl)acetone;2-Fluorophenylacetone >(o-Fluorophenyl)-2-propanone;1-(2-Fluorophenyl)-2-propanone;3-(2-Fluorophenyl)-2-propanone;1-(o-Fluorophenyl)-2-propanone
CBNumber
CB6151942
Molecular Formula
C9H9FO
Formula Weight
152.17
MOL File
2836-82-0.mol
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2-Fluorophenylacetone Property

Boiling point:
47 °C/0.05 mmHg (lit.)
Density 
1.077 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.4989(lit.)
Flash point:
185 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methyl Acetate: 50 mg/ml
form 
Liquid
color 
Pale yellow
InChI
InChI=1S/C9H9FO/c1-7(11)6-8-4-2-3-5-9(8)10/h2-5H,6H2,1H3
InChIKey
BANVZEUCJHUPOI-UHFFFAOYSA-N
SMILES
C(C1=CC=CC=C1F)C(=O)C
CAS DataBase Reference
2836-82-0(CAS DataBase Reference)
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Safety

Hazard Codes 
F
Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Flammable
HS Code 
2914.39.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0970
Product name
2-Fluorophenylacetone
Purity
>97.0%(GC)
Packaging
5g
Price
$66
Updated
2025/07/31
TCI Chemical
Product number
F0970
Product name
2-Fluorophenylacetone
Purity
>97.0%(GC)
Packaging
25g
Price
$223
Updated
2025/07/31
TRC
Product number
F595190
Product name
2-Fluorophenylacetone
Packaging
100g
Price
$1230
Updated
2021/12/16
AK Scientific
Product number
J97896
Product name
1-(2-Fluorophenyl)propan-2-one
Packaging
100g
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0009258
Product name
(2-FLUOROPHENYL)ACETONE
Purity
95.00%
Packaging
1G
Price
$603.7
Updated
2021/12/16
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2-Fluorophenylacetone Chemical Properties,Usage,Production

Chemical Properties

clear light yellow liquid

Uses

(2-Fluorophenyl)acetone was used in the synthesis of 6-methyluracils.

Uses

2-Fluorophenylacetone is used in the synthesis of antimalarial drugs.

General Description

(2-Fluorophenyl)acetone on reaction with chlorosulfonyl isocyanate yields 5-(2-fluorophenyl)-6-methyl-1,3-oxazine-2,4-(3H)-dione.

Synthesis

829-40-3

2836-82-0

General procedure for the synthesis of 2-o-fluoropropiophenone from (2-fluorophenyl)-2-nitropropene: a suspension of 1-fluoro-2-(2-nitroprop-1-en-1-yl)benzene (2054547) (160 g, 0.88 mol), powdered iron (320 g, 5.71 mol) and ferric(III) chloride (3.2 g, 19.6 mmol) in 640 ml of water, was heated to 80°C with stirring and 37% hydrochloric acid (320 ml) was added slowly over a period of 20 min. Subsequently, the reaction mixture was heated to reflux state kept for 1 hour and then cooled to room temperature. Ethyl acetate (1 L) was added and the mixture was filtered through a diatomaceous earth pad to separate the organic and aqueous layers. The organic layer was dried and concentrated and the crude product obtained was purified by distillation under reduced pressure to give 1-(2-fluorophenyl)propan-2-one (2054549) (90 g, 67% yield) with Rf = 0.40 (ethyl acetate:heptane = 1:4) and a boiling point of 70 °C (1 mmHg).

References

[1] Patent: WO2017/29104, 2017, A1. Location in patent: Page/Page column 12
[2] Chimica Therapeutica, 1968, vol. 3, p. 313 - 320

2-Fluorophenylacetone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluorophenylacetone Suppliers

Aladdin Scientific
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tp@aladdinsci.com
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United States
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58
Synthonix Inc
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Cayman Chemical Company
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Combi-Blocks Inc.
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SynQuest Laboratories, Inc.
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TCI America
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INDOFINE Chemical Company, Inc.
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HONEST JOY HOLDINGS LIMITED
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Rintech, Inc.
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Acros Organics USA
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Platte Valley Scientific, LLC
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Honeywell Specialty Chemicals Seelze GmbH
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View Lastest Price from 2-Fluorophenylacetone manufacturers

RongNa Biotechnology Co.,Ltd
Product
2-Fluorophenylacetone 2836-82-0
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
10 ton
Release date
2025-05-04
Shandong Hanjiang Chemical Co., Ltd
Product
2-Fluorophenylacetone 2836-82-0
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-19
Hebei Yanxi Chemical Co., Ltd.
Product
2-Fluorophenylacetone 2836-82-0
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-13

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