1,2-Bis(chlorodimethylsilyl)ethane

Product Name: 1,2-Bis(chlorodimethylsilyl)ethane
CAS No.: 13528-93-3
Chemical Name: 1,2-Bis(chlorodimethylsilyl)ethane
Synonyms: 1,2-Bis(chlorodimethylsilyl);1,1,4,4-TETRAMETHYL-1,4-DICHLORODISILYLETHYLENE;chloro[2-(chlorodimethylsilyl)ethyl]dimethylsilane;DK065;DK525;STABASE;SILANE BM2E;[-CH2Si(CH3)2Cl]2;Patchouli oil 8014-09-3;1,2-Bis(dimethylchlorosily)ethane
CBNumber: CB6154680
Molecular Formula: C6H16Cl2Si2
Formula Weight: 215.27
MOL File: 13528-93-3.mol

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1,2-Bis(chlorodimethylsilyl)ethane Property

Melting point:: 35-38 °C (lit.)
Boiling point:: 198 °C/734 mmHg (lit.)
Density: 0.99
Flash point:: 155 °F
storage temp.: Inert atmosphere,Room Temperature
form: Low Melting Solid
color: Transparent
Water Solubility: Reacts with water.
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
BRN: 1920141
InChIKey: VGQOKOYKFDUPPJ-UHFFFAOYSA-N
CAS DataBase Reference: 13528-93-3(CAS DataBase Reference)
EPA Substance Registry System: Silane, 1,2-ethanediylbis[chlorodimethyl- (13528-93-3)

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Safety

Hazard Codes: C
Risk Statements: 34-10
Safety Statements: 26-28-36/37/39-45-16
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
F: 10-21
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29319000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 267880
Product name: 1,2-Bis(chlorodimethylsilyl)ethane
Purity: 96%
Packaging: 25g
Price: $99.6
Updated: 2024/03/01

TCI Chemical

Product number: B1688
Product name: 1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines]
Purity: >95.0%(GC)
Packaging: 5g
Price: $47
Updated: 2024/03/01

TCI Chemical

Product number: B1688
Product name: 1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines]
Purity: >95.0%(GC)
Packaging: 25g
Price: $185
Updated: 2024/03/01

Alfa Aesar

Product number: L02570
Product name: 1,2-Bis(chlorodimethylsilyl)ethane, tech. 90%
Packaging: 25g
Price: $55.65
Updated: 2024/03/01

Alfa Aesar

Product number: L02570
Product name: 1,2-Bis(chlorodimethylsilyl)ethane, tech. 90%
Packaging: 100g
Price: $202
Updated: 2024/03/01

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1,2-Bis(chlorodimethylsilyl)ethane Chemical Properties,Usage,Production

Chemical Properties

transparent low melting solid

Physical properties

mp 36–41°C; bp 198°C/734 mmHg.

Uses

1,2-Bis(chlorodimethylsilyl)ethane is used as Protecting Reagent for Primary Amines. It is also used in Medicine field, electronics industry and polymer material.

Uses

1,2-Bis(chlorodimethylsilyl)ethane can be used as a reagent for the protection of primary amines as their tetramethyldisilylazacyclopentane or Stabase adducts; used in combination with zinc to form organozinc carbenoids; electrophilic silylating reagent.
Protection of Primary Amines.
Few protecting groups exist for the N,N-diprotection of primary amines. The tetramethyldisilylazacyclopentane or Stabase adduct (3) is particularly attractive for this purpose due to its ease of preparation, base stability and facile removal. This cyclic disilane is easily prepared (eq 1) from the commercially available title reagent (1).For primary amines with pKa values between 10 and 11, typical reaction conditions involve the treatment of a dichloromethane solution of the amine with (1) in the presence of two equivalents of triethylamine at room temperature. Subsequent workup with aqueous dihydrogen phosphate provides (3) in excellent yields.1 Stabase adducts are quite stable to strongly basic conditions such as n-butyllithium and s-butyllithium (at ?25°C), lithium diisopropylamide, and Grignard reagents making it a superb candidate for use in the alkylation of substrates bearing a primary amine. For example, protected amino acid derivatives are easily alkylated (eq 2).After formation of the lithium enolate of the protected ethyl glycinate (4) under standard conditions, exposure to various alkyl halides or aldehydes yields alkylation products such as (5).

1,2-Bis(chlorodimethylsilyl)ethane Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-Bis(chlorodimethylsilyl)ethane Suppliers

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View Lastest Price from 1,2-Bis(chlorodimethylsilyl)ethane manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1,2-Bis(chlorodimethylsilyl)ethane 96% 13528-93-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 1,2-Bis(chlorodimethylsilyl)ethane 13528-93-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

13528-93-3, 1,2-Bis(chlorodimethylsilyl)ethaneRelated Search:

1,1,2,2-Tetrachloroethane Isobutylene oxide DIMETHYLTHEXYLSILYL CHLORIDE CHLORODIMETHYLVINYLSILANE CHLOROETHANE ETHANE tert-Butyldimethylsilyl chloride Hexafluoroethane POLYDIMETHYLSILOXANE 1-Cyclohexenyloxytrimethylsilane (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE Chlorodimethylsilane ETHYLDIMETHYLSILANE Chlorotrimethylsilane TRIMETHYLSILANE ETHYLDIMETHYLCHLOROSILANE DISILANE METHYLETHYLCHLOROSILANE

1,2-Bis(chlorodimethylsily)ethane

1,2-ethanediylbis[chlorodimethyl-silan

1,2-Bis(chlorodimethylsilyl)ethane,96%

[-CH2Si(CH3)2Cl]2

1,2-Bis(dimethylchlorosily)ethane

Tetra-Methyl-Di-Chloro-Ethyl-Di-SilaneOR1,2-Bis(chlorodimethylsilyl)ethane

[Protecting Reagent for PriMary AMines]

1,2-Bis(chlorodiMethylsilyl)ethane&nbsp

1,2-Bis(chlorodiMethylsilyl)ethane, 96% 25GR

1,2-Bis(chlorodiMethylsilyl)ethane, 96% 5GR

1,2-Bis(chlorodimethylsilyl)

chloro[2-(chlorodimethylsilyl)ethyl]dimethylsilane

1,2-Bis(chlorodiMethylsilyl)ethane 96%

1,2-Bis(chlorodimethylsilyl)ethane(1,1,4,4-Tetramethyl-1,4-dichlorodisilethylene)

1,1,4,4-Tetramethyl-1,4-dichloro-disilethylene, 2,5-Dichloro-2,5-dimethyl-2,5-disilahexane

1,2-ethanediylbis[chlorodimethyl-Silane

SILANE BM2E

STABASE

1,2-BIS(CHLORODIMETHYLSILYL)ETHANE

1,2-BIS(DIMETHYLCHLOROSILYL)ETHANE

1,1,4,4-TETRAMETHYL-1,4-DICHLORODISILETHYLENE

1,1,4,4-TETRAMETHYL-1,4-DICHLORODISILYLETHYLENE

1,1,4,4-TETRAMETHYL-1,4-DICHLORO-DISYLETHYLENE

2,5-DICHLORO-2,5-DIMETHYL-2,5-DISILAHEXANE

ethylenebis[chlorodimethylsilane]

1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines]

1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines]&gt

Silane, 1,1'-(1,2-ethanediyl)bis[1-chloro-1,1-dimethyl-

Patchouli oil 8014-09-3

1,1'-(1,2-Ethanediyl)bis[1-chloro-1,1-dimethylsilane

DK065

DK525

1,1'-(1,2-Ethanediyl)bis[1-chloro-1,1-dimethylsilane

13528-93-3

-CH2SiCH32Cl2

C6H16Cl2Si2

Protection and Derivatization

Protecting and Derivatizing Reagents

Silicon-Based

Synthetic Reagents

Monochlorosilanes

Si-Cl Compounds

Si (Classes of Silicon Compounds)

Protection & Derivatization Reagents (for Synthesis)

Silicon Compounds (for Synthesis)

Monochlorosilanes

Protection & Derivatization Reagents (for Synthesis)

Si (Classes of Silicon Compounds)

Si-Cl Compounds

Silicon Compounds (for Synthesis)

Synthetic Organic Chemistry