1-(2,6-dichloropyridin-3-yl)ethanone
- Product Name
- 1-(2,6-dichloropyridin-3-yl)ethanone
- CAS No.
- 412018-50-9
- Chemical Name
- 1-(2,6-dichloropyridin-3-yl)ethanone
- Synonyms
- 1-(2,6-Dichloropyridin-3-yl);3-Acetyl-2,6-dichloropyridine;1-(2,6-Dichloro-3-pyridyl)ethanone;1-(2,6-dichloropyridin-3-yl)ethanone;1-(2,6-Dichloro-3-pyridinyl)-ethanone;ETHANONE, 1-(2,6-DICHLORO-3-PYRIDINYL)-;1-(2,6-dichloropyridin-3-yl)ethan-1-one
- CBNumber
- CB61555446
- Molecular Formula
- C7H5Cl2NO
- Formula Weight
- 190.03
- MOL File
- 412018-50-9.mol
1-(2,6-dichloropyridin-3-yl)ethanone Property
- Boiling point:
- 286.7±35.0 °C(Predicted)
- Density
- 1.376±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -4.81±0.10(Predicted)
- Appearance
- Off-white to yellow Solid-liquid mixture
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D438365
- Product name
- 1-(2,6-Dichloropyridin-3-yl)ethanone
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FD144036
- Product name
- 1-(2,6-Dichloropyridin-3-yl)ethanone
- Packaging
- 1g
- Price
- $252
- Updated
- 2021/12/16
- Product number
- FD144036
- Product name
- 1-(2,6-Dichloropyridin-3-yl)ethanone
- Packaging
- 250mg
- Price
- $82.5
- Updated
- 2021/12/16
- Product number
- FD144036
- Product name
- 1-(2,6-Dichloropyridin-3-yl)ethanone
- Packaging
- 2g
- Price
- $438
- Updated
- 2021/12/16
- Product number
- 070781
- Product name
- 1-(2,6-Dichloropyridin-3-yl)ethan-1-one
- Purity
- 97%
- Packaging
- 1g
- Price
- $487
- Updated
- 2021/12/16
1-(2,6-dichloropyridin-3-yl)ethanone Chemical Properties,Usage,Production
Synthesis
917-64-6
873936-98-2
412018-50-9
To a solution of 2,6-dichloro-N-methoxy-N-methylnicotinamide (487 mg) obtained in step (1) in tetrahydrofuran (10 mL) was slowly added methylmagnesium iodide (1.24 mL, 2M ethyl ether solution) at 0 °C. The reaction mixture was then warmed to 70 °C with continuous stirring for 72 hours. Upon completion of the reaction, the reaction was quenched by adding saturated aqueous ammonium chloride solution to the mixture and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate, filtered and the filtrate concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography to give the final 2,6-dichloro-3-acetylpyridine (205 mg) as a colorless oil. The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 7.93 (1H, d, J = 8.1 Hz), 7.37 (1H, d, J = 8.1 Hz), 2.71 (3H, s). ESI-MS analysis showed a molecular ion peak of 190 [M + H]+.
References
[1] Patent: EP2669270, 2013, A1. Location in patent: Paragraph 0880-0882
[2] Patent: EP2878594, 2015, A1. Location in patent: Paragraph 0873; 0874
[3] Patent: WO2016/57834, 2016, A1. Location in patent: Paragraph 000591; 000601
1-(2,6-dichloropyridin-3-yl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-(2,6-dichloropyridin-3-yl)ethanone Suppliers
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- Country
- United Kingdom
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View Lastest Price from 1-(2,6-dichloropyridin-3-yl)ethanone manufacturers
- Product
- 3-Acetyl-2,6-dichloropyridine 412018-50-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.0001kg
- Purity
- 98%min
- Supply Ability
- 100kgs/month
- Release date
- 2022-05-10