ChemicalBook > CAS DataBase List > (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

Product Name
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
CAS No.
23735-43-5
Chemical Name
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
Synonyms
(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE;Travoprost Impurity 51;(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;L-α,β-Isopropylideneglycerol-γ-tosylate;(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE;(S)-3-Toxyloxy-1,2-propanediol acetonide;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;(S)-1-O-tosyl-2,3-O-isopropylideneglycerol;(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
CBNumber
CB6164890
Molecular Formula
C13H18O5S
Formula Weight
286.34
MOL File
23735-43-5.mol
More
Less

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Property

Melting point:
29-31 °C
alpha 
4.2 º (c=10, abs.alcohol)
Boiling point:
398.71°C (rough estimate)
Density 
1.208 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.506(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
form 
powder to lump to clear liquid
color 
White or Colorless to Light yellow
optical activity
[α]26/D +7.5°, c = 2% in DMF
BRN 
89799
CAS DataBase Reference
23735-43-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
F 
10-21
HS Code 
29329990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
337420
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
Purity
97%
Packaging
1g
Price
$171
Updated
2023/01/07
Sigma-Aldrich
Product number
337420
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
Purity
97%
Packaging
5g
Price
$304
Updated
2023/01/07
TCI Chemical
Product number
D2550
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Purity
>98.0%(GC)
Packaging
1g
Price
$198
Updated
2024/03/01
TCI Chemical
Product number
D2550
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Purity
>98.0%(GC)
Packaging
5g
Price
$645
Updated
2024/03/01
TRC
Product number
D469555
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Packaging
1g
Price
$115
Updated
2021/12/16
More
Less

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Suppliers

Americas 1 Belgium 2 China 101 Europe 1 France 1 Germany 5 India 9 Japan 3 Slovakia 2 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 8 United States 27 Global 164
Interchim S.A.
Tel
--
Fax
--
Email
interchim@interchim.com
Country
France
ProdList
6302
Advantage
76

23735-43-5, (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonateRelated Search:

ETHANE Dimethyl sulfoxide Methanol Xylene Dimethyl sulfate Dimethyl phthalate Sulfanilic acid N,N-Dimethylformamide Calcium dobesilate Amlodipine Besylate p-Toluenesulfonic acid Dimethyl ether Dodecylbenzenesulphonic acid Benzenesulfonic acid Linear alkyl benzenesulphonate Dimethyl carbonate Dimethyl fumarate Dacthal

  • (S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE
  • (S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE
  • (S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE
  • (S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE
  • (S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE
  • (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE
  • (S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate
  • 2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE
  • 2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE
  • 1,3-DIOXOLANE-4-METHANOL, 2,2-DIMETHYL-, 4-METHYLBENZENESULFONATE, (4S)-
  • L-α,β-Isopropylideneglycerol-γ-tosylate
  • (S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate
  • (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOLUENE-4-SULFONATE
  • (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE
  • (S)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-YLMETHYL P-TOLUENESULFONATE
  • (S)-1,2-O-ISOPROPYLIDENEGLYCEROL-3-TOLUENESULFONATE
  • (S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE
  • (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
  • (S)-3-Toxyloxy-1,2-propanediol acetonide
  • (s)-2,2-dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate
  • (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-toluenesulfo
  • 2,3-Isopropylidene-sn-glycerol 1-tosylate, (S)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate, L-α,β-Isopropylideneglycerol-γ-tosylate
  • 2,3-Isopropylidene-sn-glycerol 1-tosylate, L-α,β-Isopropylideneglycerol-γ-tosylate
  • (2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
  • 4-Methylbenzenesulfonic acid (S)-2,2-dimethyl-1,3-dioxolane-4α-ylmethyl ester
  • p-Toluenesulfonic acid [(S)-2,2-dimethyl-1,3-dioxolane-4α-yl]methyl ester
  • p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolan-4-ylmethyl ester
  • p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolane-4-ylmethyl ester
  • (S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate,97%
  • L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL-GAMMA-TOSYLATE
  • L-(+)-1,2-ISOPROPYLIDENEGLYCEROL 3-(P-TOLUENESULFONATE)
  • (4S)-2,2-dimethyl-4-(4-toluenesulphonyloxymethyl)-1,3-dioxolane
  • (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethylp-Toluenesulfonate&gt
  • 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-(4-methylbenzenesulfonate), (4S)-
  • Travoprost Impurity 51
  • (S)-(2,2-dimethyl-1,3-dioxalan-4-yl)methyl-4-methylbenzenesulfonate
  • (S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-tolue...
  • (S)-1-O-tosyl-2,3-O-isopropylideneglycerol
  • 23735-43-5
  • Asymmetric Synthesis
  • Organic Building Blocks
  • Protected Alcohols
  • Dioxolanes
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
  • chiral
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
  • Synthetic Organic Chemistry
  • ADVANCED INT.