(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

Product Name: (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
CAS No.: 23735-43-5
Chemical Name: (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
Synonyms: (S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE;Travoprost Impurity 51;(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;L-α,β-Isopropylideneglycerol-γ-tosylate;(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE;(S)-3-Toxyloxy-1,2-propanediol acetonide;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;(S)-1-O-tosyl-2,3-O-isopropylideneglycerol;(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
CBNumber: CB6164890
Molecular Formula: C13H18O5S
Formula Weight: 286.34
MOL File: 23735-43-5.mol

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(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Property

Melting point:: 29-31 °C
alpha: 4.2 º (c=10, abs.alcohol)
Boiling point:: 398.71°C (rough estimate)
Density: 1.208 g/mL at 25 °C(lit.)
refractive index: n20/D 1.506(lit.)
Flash point:: >230 °F
storage temp.: Inert atmosphere,2-8°C
form: powder to lump to clear liquid
color: White or Colorless to Light yellow
optical activity: [α]26/D +7.5°, c = 2% in DMF
BRN: 89799
CAS DataBase Reference: 23735-43-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
F: 10-21
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 337420
Product name: (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
Purity: 97%
Packaging: 1g
Price: $171
Updated: 2023/01/07

Sigma-Aldrich

Product number: 337420
Product name: (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
Purity: 97%
Packaging: 5g
Price: $304
Updated: 2023/01/07

TCI Chemical

Product number: D2550
Product name: (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Purity: >98.0%(GC)
Packaging: 1g
Price: $198
Updated: 2024/03/01

TCI Chemical

Product number: D2550
Product name: (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Purity: >98.0%(GC)
Packaging: 5g
Price: $645
Updated: 2024/03/01

TRC

Product number: D469555
Product name: (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Packaging: 1g
Price: $115
Updated: 2021/12/16

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(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Suppliers

Americas 1 Belgium 2 China 101 Europe 1 France 1 Germany 5 India 9 Japan 3 Slovakia 2 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 8 United States 27 Global 164

Georganics Ltd.

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Georganics Ltd.

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23735-43-5, (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonateRelated Search:

ETHANE Dimethyl sulfoxide Methanol Xylene Dimethyl sulfate Dimethyl phthalate Sulfanilic acid N,N-Dimethylformamide Calcium dobesilate Amlodipine Besylate p-Toluenesulfonic acid Dimethyl ether Dodecylbenzenesulphonic acid Benzenesulfonic acid Linear alkyl benzenesulphonate Dimethyl carbonate Dimethyl fumarate Dacthal

(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE

(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE

(S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE

(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE

(S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE

(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE

(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate

2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE

2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE

1,3-DIOXOLANE-4-METHANOL, 2,2-DIMETHYL-, 4-METHYLBENZENESULFONATE, (4S)-

L-α,β-Isopropylideneglycerol-γ-tosylate

(S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate

(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOLUENE-4-SULFONATE

(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE

(S)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-YLMETHYL P-TOLUENESULFONATE

(S)-1,2-O-ISOPROPYLIDENEGLYCEROL-3-TOLUENESULFONATE

(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

(S)-3-Toxyloxy-1,2-propanediol acetonide

(s)-2,2-dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-toluenesulfo

2,3-Isopropylidene-sn-glycerol 1-tosylate, (S)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate, L-α,β-Isopropylideneglycerol-γ-tosylate

2,3-Isopropylidene-sn-glycerol 1-tosylate, L-α,β-Isopropylideneglycerol-γ-tosylate

(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol

4-Methylbenzenesulfonic acid (S)-2,2-dimethyl-1,3-dioxolane-4α-ylmethyl ester

p-Toluenesulfonic acid [(S)-2,2-dimethyl-1,3-dioxolane-4α-yl]methyl ester

p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolan-4-ylmethyl ester

p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolane-4-ylmethyl ester

(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate,97%

L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL-GAMMA-TOSYLATE

L-(+)-1,2-ISOPROPYLIDENEGLYCEROL 3-(P-TOLUENESULFONATE)

(4S)-2,2-dimethyl-4-(4-toluenesulphonyloxymethyl)-1,3-dioxolane

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethylp-Toluenesulfonate&gt

1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-(4-methylbenzenesulfonate), (4S)-

Travoprost Impurity 51

(S)-(2,2-dimethyl-1,3-dioxalan-4-yl)methyl-4-methylbenzenesulfonate

(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-tolue...

(S)-1-O-tosyl-2,3-O-isopropylideneglycerol

23735-43-5

Asymmetric Synthesis

Organic Building Blocks

Protected Alcohols

Dioxolanes

Chiral Building Blocks

Dioxanes & Dioxolanes

Glycidyl Compounds, etc. (Chiral)

chiral

Chiral Building Blocks

Dioxanes & Dioxolanes

Dioxolanes

Glycidyl Compounds, etc. (Chiral)

Synthetic Organic Chemistry

ADVANCED INT.