N-ACETYL-3-MERCAPTO-D-VALINE Property

Melting point:

185-190 °C (dec.)

Boiling point:

392.7±37.0 °C(Predicted)

Density 

1.201±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Ethanol (Slightly), Methanol (Slightly), Trifluoroacetic Acid (Slightly)

form 

Solid

pka

3.39±0.10(Predicted)

color 

White to Off-White

optical activity

[α]20/D +10±2°, c = 1% in ethanol

Merck 

13,100

BRN 

1724742

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

10-23

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

N-ACETYL-3-MERCAPTO-D-VALINE Chemical Properties,Usage,Production

Uses

Protected Penicillamin.

Definition

ChEBI: An N-acetyl-D-amino acid where the amino acid is D-penicillamine

Purification Methods

Both forms are recrystallised from hot H2O. A pure sample of the D-form is obtained after five recrystallisations. [Crooks in The Chemistry of Penicillin Clarke, Johnson and Robinson eds, Princeton University Press, 470 1949, Review: Chain et al. Antibiotics (Oxford University Press) 2 1949, Beilstein 4 III 1662.]