ChemicalBook > CAS DataBase List > Tetrahydroberberine

Tetrahydroberberine

Product Name
Tetrahydroberberine
CAS No.
522-97-4
Chemical Name
Tetrahydroberberine
Synonyms
THB;Nsc94918;CANADINE;l-Canadine;AKOS 213-56;DL-CANADINE;tetrahedron;Xanthopuccine;l-Xanthopuccine;Tetrahydroberine
CBNumber
CB6195104
Molecular Formula
C20H21NO4
Formula Weight
339.39
MOL File
522-97-4.mol
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Tetrahydroberberine Property

Melting point:
166.5 °C
Boiling point:
476.1±45.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: >10 mg/mL, soluble
form 
solid
pka
6.53±0.20(Predicted)
color 
yellow
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
Toxicity
LD50 in mice (mg/kg): 940 orally; 790 s.c.; 100 i.v. (Sadritdinov, Sultanov)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C175175
Product name
Canadine
Packaging
10mg
Price
$160
Updated
2021/12/16
TRC
Product number
C175175
Product name
Canadine
Packaging
100mg
Price
$1295
Updated
2021/12/16
ApexBio Technology
Product number
N2130
Product name
Tetrahydroberberine,THB
Packaging
20mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC19659
Product name
Canadine
Packaging
10mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC19659
Product name
Canadine
Packaging
25mg
Price
$300
Updated
2021/12/16
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Tetrahydroberberine Chemical Properties,Usage,Production

Uses

Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.

Uses

Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.

Definition

ChEBI: A berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10.

Tetrahydroberberine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tetrahydroberberine manufacturers

Dideu Industries Group Limited
Product
Tetrahydroberberine 522-97-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-21
Shaanxi Dideu Medichem Co. Ltd
Product
Tetrahydroberberine 522-97-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
800 tons
Release date
2020-05-01
Career Henan Chemical Co
Product
TETRAHYDROBERBERINE 522-97-4
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10000kg
Release date
2018-08-10

522-97-4, TetrahydroberberineRelated Search:

(-)-Huperzine A Leflunomide Formoterol fumarate dihydrate Artemisinin Andrographolide Berbamine hydrochloride BERBERINE CHLORIDE Rotundine epiberberine Coptisine chloride Berberine hydrochloride TETRAHYDROBERBERINE(CANADINE)(P),TETRAHYDROBERBERINE(CANADINE)(P) 7-(4-chlorobenzyl)-7,8,13,13a-tetrahydroberberine DL-TETRAHYDROBERBERINE,TETRAHYDROBERBERINE,CANADINE,DL-CANADINE .Alpha.-Canadine methochloride 1-tetrahydroberberine-camphor sulfonate canadine hydrochloride (D,L)-TETRAHYDROBERBERINE(CANADINE),(D,L)-TETRAHYDROBERBERINE(CANADINE)

  • (13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
  • l-Canadine
  • l-Tetrahydroberberine
  • l-Xanthopuccine
  • 6H-Benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine, 5,8,13,13A-tetrahydro-9,10-dimethoxy-
  • Berberine, tetrahydro-
  • Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-
  • Nsc94918
  • Xanthopuccine
  • Tetrahydroberberine,THB
  • 9,10-DiMethoxy-2,3-(Methylenedioxy)berbine
  • 9-Deoxy-16,17-dihydroberberine
  • Tetrahydroberberine, BR
  • TETRAHYDROBERBERINE
  • Tetrahydroberberine, Canadine
  • Canadine, THB, 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-alpha]quinolizine
  • 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
  • Tetrahydroberberine, 98%, from Coptis chinensis Franch.
  • dl-Tetrahydroberberine 〔dl-Canadine〕
  • 9,10-DIMETHOXY-5,8,13,13A-TETRAHYDRO-6H-[1,3]DIOXOLO[4,5-G]ISOQUINO[3,2-A]ISOQUINOLINE
  • AKOS 213-56
  • 5,8,13,13A-TETRAHYDRO-9,10-DIMETHOXY-6H-BENZO[G]-1,3-BENZODIOXOLO[5,6-ALPHA]QUINOLIZINE
  • CANADINE
  • DL-TETRAHYDROBERBERINE
  • DL-CANADINE
  • THB
  • 5,8,13,13a-tetrahydro-9,10-dimethoxy-6H-benzo[g]benzo-1,3-dioxolo[5,6-a]quinolizine
  • Tetrahydroberberine USP/EP/BP
  • tetrahedron
  • 5,8,13,13a-tetrahydro-9,10-dimethoxy-6H-benzo[g]benzo-1,3-di...
  • 9,10-Dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline
  • Tetrahydroberine
  • 522-97-4
  • C20H21O4N
  • Inhibitors
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pharmaceuticals