SINOMENINE HYDROCHLORIDE

Product Name: SINOMENINE HYDROCHLORIDE
CAS No.: 6080-33-7
Chemical Name: SINOMENINE HYDROCHLORIDE
Synonyms: Sinomenin HCl;SINOMENINE HCL;Cucoline hydrochloride;Kukoline hydrochloride;Sinomenine Hydrocloride;SINOMENINE HYDROCHLORIDE;Tuduranine Hydrochloride;Sinomenine HCl Dihydrate;Sabianine A hydrochloride;Sinomenine hydrochloride-RM
CBNumber: CB6245173
Molecular Formula: C19H23NO4.ClH
Formula Weight: 365.85
MOL File: 6080-33-7.mol

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SINOMENINE HYDROCHLORIDE Property

Melting point:: 231.0 to 235.0 °C
storage temp.: Inert atmosphere,2-8°C
solubility: H2O: soluble20mg/mL, clear
form: powder
color: white to beige
optical activity: [α]/D -70 to -90°, c = 1 in H2O
Water Solubility: Soluble to 100 mM in water

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: QD2163000
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1002
Product name: Sinomenine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $118
Updated: 2024/03/01

TCI Chemical

Product number: S0926
Product name: Sinomenine Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $117
Updated: 2023/01/07

TCI Chemical

Product number: S0926
Product name: Sinomenine Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $402
Updated: 2022/04/27

Cayman Chemical

Product number: 16143
Product name: Sinomenine (hydrochloride)
Purity: ≥98%
Packaging: 50mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 16143
Product name: Sinomenine (hydrochloride)
Purity: ≥98%
Packaging: 100mg
Price: $44
Updated: 2024/03/01

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SINOMENINE HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Sinomenine is a natural plant alkaloid commonly used to alleviate inflammation associated with rheumatoid arthritis. It activates histamine release, reduces joint stiffness and pain, and alters cytokine generation without producing gastrointestinal adverse events. Sinomenine also impairs signaling through NF-κB, resulting in immunosuppression as well as reduced inflammation and pain. It enhances the bioavailability of some compounds, at least in part through an inhibition of drug export by transporters like P-glycoprotein.

Chemical Properties

White Solid

Uses

Sinomenine is an optical isomer of Methoxythebainone. Sinomenine was extracted from root of Sinomenium acutum. Sinomenine has anti-inflammatory and analgesic effect.

Purification Methods

Crystallise the salt from water (1g/1.5mL) or EtOH. The free base [115-53-7] M 329.4, has m 161o (from EtOH) (and again at 182o) after crystallisation from *C6H6, and [] D 20 -78.9o (c 1, EtOH). The picrate has m 159-162o(dec) (from H2O). [Beilstein 21 II 470, 21 III/IV 6670.]

SINOMENINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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SINOMENINE HYDROCHLORIDE Suppliers

Canada 1 China 185 Europe 2 Germany 1 India 4 Japan 1 United Kingdom 6 United States 22 Global 222

EMMX Biotechnology LLC

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View Lastest Price from SINOMENINE HYDROCHLORIDE manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Sinomenine Hydrochloride 6080-33-7
Price: US $200.00-85.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-23

Hovane Phytochemicals Co., Ltd

Product: Sinomenine Hydrochloride 6080-33-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%HPLC
Supply Ability: 1 ton
Release date: 2024-11-20

Hebei Kingfiner Technology Development Co.Ltd

Product: SINOMENINE HYDROCHLORIDE 6080-33-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 50000kg
Release date: 2023-07-28

6080-33-7, SINOMENINE HYDROCHLORIDERelated Search:

Fingolimod hydrochloride Oxyresveratrol PHELLODENDRINE CHLORIDE Cucurbitacin IIb Palmatine chloride Ursolic acid TETRAHYDROPALMATINE HYDROCHLORIDE Arbutin Corydaline Lycorine hydrochloride SECO-ISOLARICIRESINOL DIGLUCOSIDE Betaine hydrochloride STACHYDRINE HYDROCHLORIDE 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Berberine hydrochloride SANGUINARINE Ligustrazine Hydrochloride JATRORRHIZINE HCL(RG)

hydroxy-dimethoxy-methyl-BLAH-azatetracyclo[BLAH]hexadeca-BLAH,BLAH,BLAH,BLAH-tetraenone

Sinomenine Hydrocloride

Cucoline hydrochloride

(9a,13a,14a)-4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride

SINOMENINE HYDROCHLORIDE

SINOMENINE HCL

(9α,13α,14α)- 7,8-Didehydro-4- hydroxy-3,7-diMet

7,8-Didehydro-4-hydroxy-3,7-diMethoxy-17-Methyl- 9α,13α,14α-Morphinan-6-one Hydrochloride

Tuduranine Hydrochloride

Sinomenine hydrochloride (Cucoline hydrochloride)

Sinomenine Hydrochloride &gt

Kukoline hydrochloride

Sabianine A hydrochloride

9α,13α,14α-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride

TIANFU-CHEM CAS:6080-33-7 SINOMENINE HYDROCHLORIDE

Sinomenine hydrochloride (Cucoline)

Sinomenine HCl Dihydrate

Sinomenine hydrochloride (6CI, 7CI)

Sinomenin HCl

98% Sinomenine Hydrochloride Powder

Sinomenine Hydrochloride, ≥ 98.0%

Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride (1:1), (9α,13α,14α)-

(4bR,8aS,9S)-4-Hydroxy-3,7-dimethoxy-11-methyl-9,10-dihydro-5H-9,4b-(epiminoethano)phenanthren-6(8aH)-one hydrochloride

Sinomenine hydrochloride-RM

6080-33-7

C19H23NO4HCl

Alkaloids

Inhibitors

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

chemical reagent

Chiral Reagents

Intermediates & Fine Chemicals

Pharmaceuticals

APIs