4-Methoxy-indoline-2,3-dione
- Product Name
- 4-Methoxy-indoline-2,3-dione
- CAS No.
- 108937-87-7
- Chemical Name
- 4-Methoxy-indoline-2,3-dione
- Synonyms
- Isalexin;4-Methoxyindole-2,3-dione;4-Methoxy-indoline-2,3-dione;4-Methoxy-1H-Indole-2,3-dione;1H-Indole-2,3-dione, 4-methoxy-;2,3-Dihydro-4-methoxy-1H-indole-2,3-dione
- CBNumber
- CB62598505
- Molecular Formula
- C9H7NO3
- Formula Weight
- 177.16
- MOL File
- 108937-87-7.mol
4-Methoxy-indoline-2,3-dione Property
- Density
- 1.346±0.06 g/cm3(Predicted)
- storage temp.
- Store at room temperature
- pka
- 9.33±0.20(Predicted)
- Appearance
- Yellow to orange Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M269778
- Product name
- 4-Methoxyindoline-2,3-dione
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- Y7009
- Product name
- 4-Methoxyindoline-2,3-dione
- Packaging
- 250mg
- Price
- $259
- Updated
- 2021/12/16
- Product number
- CHM0383248
- Product name
- 4-METHOXYINDOLINE-2,3-DIONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.8
- Updated
- 2021/12/16
- Product number
- 50156
- Product name
- 4-METHOXYINDOLINE-2,3-DIONE
- Purity
- 95%
- Packaging
- 0.1/ G
- Price
- $118
- Updated
- 2021/12/16
- Product number
- AA0082V7
- Product name
- 4-Methoxyindoline-2,3-dione
- Purity
- 95%
- Packaging
- 100mg
- Price
- $120
- Updated
- 2021/12/16
4-Methoxy-indoline-2,3-dione Chemical Properties,Usage,Production
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 7303, 1994 DOI: 10.1016/0040-4039(94)85299-5
Synthesis
4837-90-5
108937-87-7
General procedure for the synthesis of 4-methoxyindoline-2,3-dione from 4-methoxyindole: 4-methoxyindole (18.25 mg, 0.17 mmol, 1.0 eq.) was dissolved in 1,2-dichloroethane (DCE) (2 mL), which was subsequently added to a solution containing pyridinium chlorochromate (PCC) (273 mg, 1.36 mmol, 8.0 equivalents) in a DCE solution (2 mL) and aluminum chloride (7 mg, 0.05 mmol, 0.3 equivalents) was added. The reaction mixture was heated at 80 °C for 2 h and then concentrated to dryness. The residue was purified by fast column chromatography (FCC) (eluent: ethyl acetate-hexane, 1:1) to afford 4-methoxyindoline-2,3-dione (16 mg, 0.09 mmol, 53% yield) in yellow powder form. The spectral data of the obtained compound were in agreement with literature reports.
References
[1] RSC Advances, 2015, vol. 5, # 46, p. 37018 - 37022
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 2, p. 1 - 22
4-Methoxy-indoline-2,3-dione Preparation Products And Raw materials
Raw materials
Preparation Products
4-Methoxy-indoline-2,3-dione Suppliers
- Tel
- 8485655694
- sales@alchempharmtech.com
- Country
- United States
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- 63687
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