ChemicalBook > CAS DataBase List > ML 161

ML 161

Product Name
ML 161
CAS No.
423735-93-7
Chemical Name
ML 161
Synonyms
ML 161;CS-1106;Parmodulin 2;ML161, >=98%;ML161;ML-161;ML161 (Parmodulin 2);2-Bromo-N-(3-butanamidophenyl)benzamide;2-BroMo-N-(3-butyraMidophenyl)benzaMide;2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide;Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-
CBNumber
CB62629267
Molecular Formula
C17H17BrN2O2
Formula Weight
361.23
MOL File
423735-93-7.mol
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ML 161 Property

Boiling point:
465.7±30.0 °C(Predicted)
Density 
1.441±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL (clear solution)
pka
12.37±0.70(Predicted)
form 
powder
color 
white to beige
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Safety

RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0418
Product name
ML-161
Purity
≥98% (HPLC)
Packaging
5mg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0418
Product name
ML-161
Purity
≥98% (HPLC)
Packaging
25mg
Price
$347
Updated
2024/03/01
Cayman Chemical
Product number
15179
Product name
ML-161
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
15179
Product name
ML-161
Purity
≥95%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
15179
Product name
ML-161
Purity
≥95%
Packaging
10mg
Price
$153
Updated
2024/03/01
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ML 161 Chemical Properties,Usage,Production

Description

ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 μM. It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA , U-46619 , or collagen.

Uses

ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation.

Definition

ChEBI: 2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide is a member of benzamides.

References

[1]. dockendorff, c., et al., discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the par1 receptor. acs med chem lett, 2012. 3(3): p. 232-237.
[2]. verplank, l., et al., chemical genetic analysis of platelet granule secretion-probe 3, in probe reports from the nih molecular libraries program. 2010, national center for biotechnology information (us): bethesda (md).

ML 161 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML 161 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Tianjin YongSheng Biotechnology Co., Ltd.
Tel
022-60987737 13512258274
Fax
86-022-23500597
Email
sales@immortalbio.com
Country
China
ProdList
154
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
SALES@UHNSHANGHAI.COM
Country
China
ProdList
977
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
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View Lastest Price from ML 161 manufacturers

Career Henan Chemical Co
Product
ML 161 423735-93-7
Price
US $5.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-09-03

423735-93-7, ML 161Related Search:


  • ML 161
  • 2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide
  • 2-BroMo-N-(3-butyraMidophenyl)benzaMide
  • Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-
  • ML 161 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide
  • ML161;ML-161
  • ML161, >=98%
  • Parmodulin 2
  • CS-1106
  • 2-Bromo-N-(3-butanamidophenyl)benzamide
  • ML161 (Parmodulin 2)
  • 423735-93-7
  • Inhibitors