ChemicalBook > CAS DataBase List > ML 161

ML 161

Product Name
ML 161
CAS No.
423735-93-7
Chemical Name
ML 161
Synonyms
ML 161;CS-1106;Parmodulin 2;ML161, >=98%;ML161;ML-161;ML161 (Parmodulin 2);2-Bromo-N-(3-butanamidophenyl)benzamide;2-BroMo-N-(3-butyraMidophenyl)benzaMide;2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide;Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-
CBNumber
CB62629267
Molecular Formula
C17H17BrN2O2
Formula Weight
361.23
MOL File
423735-93-7.mol
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ML 161 Property

Boiling point:
465.7±30.0 °C(Predicted)
Density 
1.441±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL (clear solution)
pka
12.37±0.70(Predicted)
form 
powder
color 
white to beige
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Safety

RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0418
Product name
ML-161
Purity
≥98% (HPLC)
Packaging
5mg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0418
Product name
ML-161
Purity
≥98% (HPLC)
Packaging
25mg
Price
$347
Updated
2024/03/01
Cayman Chemical
Product number
15179
Product name
ML-161
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
15179
Product name
ML-161
Purity
≥95%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
15179
Product name
ML-161
Purity
≥95%
Packaging
10mg
Price
$153
Updated
2024/03/01
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ML 161 Chemical Properties,Usage,Production

Description

ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 μM. It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA , U-46619 , or collagen.

Uses

ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation.

Definition

ChEBI: 2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide is a member of benzamides.

References

[1]. dockendorff, c., et al., discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the par1 receptor. acs med chem lett, 2012. 3(3): p. 232-237.
[2]. verplank, l., et al., chemical genetic analysis of platelet granule secretion-probe 3, in probe reports from the nih molecular libraries program. 2010, national center for biotechnology information (us): bethesda (md).

ML 161 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML 161 Suppliers

Target molecule Corp.
Tel
857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
Country
United States
ProdList
2559
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
NE Scientific
Tel
--
Fax
--
Country
United States
ProdList
5030
Advantage
55
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View Lastest Price from ML 161 manufacturers

Career Henan Chemical Co
Product
ML 161 423735-93-7
Price
US $5.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-09-03

423735-93-7, ML 161Related Search:


  • ML 161
  • 2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide
  • 2-BroMo-N-(3-butyraMidophenyl)benzaMide
  • Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-
  • ML 161 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide
  • ML161;ML-161
  • ML161, >=98%
  • Parmodulin 2
  • CS-1106
  • 2-Bromo-N-(3-butanamidophenyl)benzamide
  • ML161 (Parmodulin 2)
  • 423735-93-7
  • Inhibitors