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ASPERULOSIDE

Product Name
ASPERULOSIDE
CAS No.
14259-45-1
Chemical Name
ASPERULOSIDE
Synonyms
Nsc 31760;Asperulosid;ASPERULOSIDE;Asperuloside-RM;Einecs 238-137-5;RUBICHLORIC ACID;Asperuloside >=95% (LC/MS-ELSD);(2aS)-2a,4aα,5,7bα-Tetrahydro-4-acetoxymethyl-5α-(β-D-glucopyranosyloxy)-1H-2,6-dioxacyclopent[cd]inden-1-one;1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-;1H-2,6-Dioxacyclopentcdinden-1-one, 4-(acetyloxy)methyl-5-(.beta.-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-
CBNumber
CB6272515
Molecular Formula
C18H22O11
Formula Weight
414.36
MOL File
14259-45-1.mol
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ASPERULOSIDE Property

Melting point:
131-132°
alpha 
D25 -198.6° (c = 1.44 in water)
Boiling point:
704.2±60.0 °C(Predicted)
Density 
1.62±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in methanol and water
form 
powder
pka
12.76±0.70(Predicted)
color 
White
EPA Substance Registry System
1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(?-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)- (14259-45-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00085
Product name
Asperuloside
Purity
≥95% (LC/MS-ELSD)
Packaging
1mg
Price
$303
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL83229
Product name
Asperuloside
Purity
phyproof Reference Substance
Packaging
10mg
Price
$574
Updated
2024/03/01
Cayman Chemical
Product number
29439
Product name
Asperuloside
Packaging
5mg
Price
$382
Updated
2024/03/01
Cayman Chemical
Product number
29439
Product name
Asperuloside
Packaging
10mg
Price
$556
Updated
2024/03/01
Cayman Chemical
Product number
29439
Product name
Asperuloside
Packaging
1mg
Price
$139
Updated
2024/03/01
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ASPERULOSIDE Chemical Properties,Usage,Production

Description

Asperuloside is an iridoid glycoside that has been found in G. tunetanum and has diverse biological activities, including anti-angiogenic, anti-inflammatory, and anti-obesity properties. It reduces microvessel formation by 67% in a chick embryo chorioallantoic membrane assay when used at a concentration of 2 μg/egg. Asperuloside (20, 40, and 80 mg/L) inhibits LPS-induced increases in TNF-α, IL-1β, and IL-6 production in RAW 264.7 macrophages in a concentration-dependent manner. It reduces lung myeloperoxidase (MPO) activity and bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced acute lung injury when administered at doses of 20, 40, and 80 mg/kg. Dietary administration of asperuloside decreases body weight gain, white adipose tissue (WAT) weight, and the ratio of WAT weight to body weight in a high-fat diet-induced mouse model of metabolic syndrome.

Uses

Asperuloside is an iridoid found in Paederia foetida and is an inhibitor of xanthine oxidase and is used in the treatment of various disorders including inflammatory and cardiovascular diseases.

Definition

ChEBI: A iridoid monoterpenoid glycoside isolated from Galium verum.

ASPERULOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ASPERULOSIDE Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
Apin Chemicals Ltd.
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
Sequoia Research Products Ltd.
Tel
--
Fax
--
Email
sales@seqchem.com
Country
United Kingdom
ProdList
3113
Advantage
69
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View Lastest Price from ASPERULOSIDE manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Asperuloside 14259-45-1
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-28
Career Henan Chemical Co
Product
ASPERULOSIDE 14259-45-1
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-10

14259-45-1, ASPERULOSIDERelated Search:


  • ASPERULOSIDE
  • RUBICHLORIC ACID
  • [2aS-(2aalpha,4aalpha,5alpha,7balpha)]-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent[cd]inden-4-ylmethyl acetate
  • 1H-2,6-Dioxacyclopentcdinden-1-one, 4-(acetyloxy)methyl-5-(.beta.-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-
  • Asperulosid
  • (2aS)-2a,4aα,5,7bα-Tetrahydro-4-acetoxymethyl-5α-(β-D-glucopyranosyloxy)-1H-2,6-dioxacyclopent[cd]inden-1-one
  • (2As-(2aalpha,4aalpha,5alpha,7balpha))-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-1-oxo-1H-2,6-dioxacyclopent(cd)inden-4-ylmethyl acetate
  • 1H-2,6-Dioxacyclopent(cd)inden-1-one, 4-((acetyloxy)methyl)-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-, (2as-(2aalpha,5alpha,7balpha))-
  • Einecs 238-137-5
  • Nsc 31760
  • 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-
  • Asperuloside >=95% (LC/MS-ELSD)
  • ((2aS,2a1S,4aS,5S)-1-Oxo-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2a,2a1,4a,5-tetrahydro-1H-2,6-dioxacyclopenta[cd]inden-4-yl)methyl acetate
  • Asperuloside-RM
  • 14259-45-1
  • 14529-45-1
  • Miscellaneous Natural Products