ChemicalBook > CAS DataBase List > TEMPO

TEMPO

Product Name
TEMPO
CAS No.
2564-83-2
Chemical Name
TEMPO
Synonyms
TEMPO;TEPO;2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY;2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL;2,2,6,6-Tetramethylpiperidin-1-oxyl;(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl;2,2,6,6-TETRAMETHYLPIPERIDINE-N-OXYL;Tanane;Tanan;TEMPO,98%
CBNumber
CB6309451
Molecular Formula
C9H18NO*
Formula Weight
156.25
MOL File
2564-83-2.mol
More
Less

TEMPO Property

Melting point:
36-38 °C(lit.)
Boiling point:
193°C
Density 
1 g/cm3
vapor pressure 
0.4 hPa (20 °C)
refractive index 
1.4350 (estimate)
Flash point:
154 °F
storage temp. 
Store below +30°C.
solubility 
9.7g/l
form 
Powder
color 
Yellow to green
PH
8.3 (9g/l, H2O, 20℃)
Water Solubility 
Soluble in all organic solvents. Insoluble in water.
Merck 
14,9140
BRN 
1422418
Stability:
Stable. Incompatible with strong acids, strong oxidizing agents. Refrigerate.
InChIKey
RVWUHFFPEOKYLB-UHFFFAOYSA-N
CAS DataBase Reference
2564-83-2(CAS DataBase Reference)
NIST Chemistry Reference
1-Piperidinyloxy, 2,2,6,6-tetramethyl-(2564-83-2)
EPA Substance Registry System
1-Piperidinyloxy, 2,2,6,6-tetramethyl- (2564-83-2)
More
Less

Safety

Hazard Codes 
C,Xi
Risk Statements 
34-36/37/38
Safety Statements 
26-36/37/39-45-24/25
RIDADR 
UN 3263 8/PG 2
WGK Germany 
3
RTECS 
TN8991900
Autoignition Temperature
275 °C
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29333999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
214000
Product name
TEMPO
Purity
98%
Packaging
1g
Price
$28.2
Updated
2024/03/01
Sigma-Aldrich
Product number
214000
Product name
TEMPO
Purity
98%
Packaging
5g
Price
$64.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14681
Product name
2,2,6,6-Tetramethylpiperidine-1-oxyl (free radical)
Purity
for synthesis
Packaging
5G
Price
$108
Updated
2022/05/15
Sigma-Aldrich
Product number
8.14681
Product name
2,2,6,6-Tetramethylpiperidine-1-oxyl (free radical)
Purity
for synthesis
Packaging
25g
Price
$201
Updated
2022/05/15
TCI Chemical
Product number
T1560
Product name
2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$45
Updated
2024/03/01
More
Less

TEMPO Chemical Properties,Usage,Production

Description

2,2,6,6-Tetramethylpiperidine is a product that is used for the most diverse purposes because of its strong basicity, for example, as a light stabilizer for polyolefins, as a cocatalyst in olefin polymerizations (Ziegler catalysts), as a building block for the synthesis of pharmaceuticals and crop protection products, as a cocatalyst in the synthesis of dichloroacetyl chloride. The 4-unsubstituted 2.2.6,6-tetramethylpiperidine is generally prepared from the corresponding 4-oxo compound. It is known that triacetonamine can be converted by hydrazine to the hydrazone, which is then cleaved in the presence of alkali into 2,26,6-tetramethylpiperidine and nitrogen.

Chemical Properties

orange crystals or powder

Characteristics

2,2,6,6-Tetramethylpiperidinooxy(TEMPO) has the characteristics of high yield, good selectivity, good stability, and recyclable use.

Uses

TEMPO(2,2,6,6-Tetramethylpiperidinooxy) is a stable radical prepared through the oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO has a wide range of applications including use as a free radical scavenger, a reagent in organic synthe sis and as a structural probe in electron spin resonance spectroscopy. TEMPO can also be used as a mediator in free radical polymerization.

Uses

In organic chemistry as a radical trap, 2,2,6,6-Tetramethylpiperidinooxy can be used as a catalyst and in polymerization mediation.

Uses

TEMPO can be used:

  • As a catalytic oxidant for copper-catalyzed, greener oxidation of alcohols under aerobic conditions.
  • As a catalytic oxidant in the iodobenzene diacetae oxidation of nerol to neral.
  • For trapping the styrenyl radical generated from benzoyl peroxide during nitroxide-mediated radical polymerization of styrene.
  • In the carboxylation of water-resistant nanofibrillated cellulose (NFC) films.

Copper(I)/TEMPO-catalyzed aerobic oxidation of primary alcohols to aldehydes with ambient air

General Description

For a synthetic protocol using NMP initiators, contributed by Prof. Karen Wooley, please visit our technology spotlight.

Purification Methods

Purify TEMPO by sublimation (33o, water aspirator) [Hay & Fincke J Am Chem Soc 109 8012 1987, Keana Chem Rev 78 37 1978].

TEMPO Preparation Products And Raw materials

Raw materials

2,2,6,6-Tetramethylpiperidine Hydrogen peroxide Phosphotungstic acid hydrate Diethyl ether CALCIUM SULFATE Sulfuric acid

Preparation Products

MORPHOLINE-3,4-DICARBOXYLIC ACID 4-TERT-BUTYL ESTER Cyclopropanecarboxaldehyde 4-tert-Butylcyclohexanone (S)-4-BOC-MORPHOLINE-3-CARBOXYLIC ACID
More
Less

TEMPO Suppliers

Belgium 3 Canada 2 China 493 Europe 3 France 2 Germany 14 India 53 Italy 1 Japan 9 Poland 3 Slovakia 2 South Korea 2 Switzerland 4 The Netherlands 1 United Kingdom 18 United States 51 Global 661
BTC pharm India
Tel
+918790379245
Email
banny.janga@btcpharm.com
Country
India
ProdList
1262
Advantage
58
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
marketing@srlchem.com
Country
India
ProdList
4315
Advantage
58
Triveni chemicals
Tel
--
Fax
--
Email
sales@trivenichemical.com
Country
India
ProdList
6088
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
VASIN BIO LIFE SCIENCES PVT LTD
Tel
--
Fax
--
Email
info@vasinbio.com
Country
India
ProdList
2092
Advantage
58
Saradhi Organics
Tel
--
Fax
--
Email
sales@saradhiorganics.com
Country
India
ProdList
183
Advantage
58
Arham Enterprise
Tel
--
Fax
--
Country
India
ProdList
53
Advantage
58
Sai Quest Syn. Ltd
Tel
--
Fax
--
Country
India
ProdList
268
Advantage
58
Loba Chemie Pvt., Ltd.
Tel
--
Fax
--
Email
@lobachemie.com
Country
India
ProdList
765
Advantage
58
Innovative
Tel
--
Fax
--
Country
India
ProdList
617
Advantage
58
Laurel Pharma Labs
Tel
--
Fax
--
Country
India
ProdList
25
Advantage
58
HiMedia Laboratories
Tel
--
Fax
--
Email
o@himedialabs.com
Country
India
ProdList
1841
Advantage
58
Suvchem
Tel
--
Fax
--
Email
sales@suvchem.com
Country
India
ProdList
180
Advantage
58
Azole Rasayanas India Private Limited
Tel
--
Fax
--
Email
info@azolerasayanas.com
Country
India
ProdList
681
Advantage
58
Anand Agencies
Tel
--
Fax
--
Email
en@gmail.com
Country
India
ProdList
2332
Advantage
58
S. R. Chemical Specialities
Tel
--
Fax
--
Country
India
ProdList
90
Advantage
58
ASM Organics
Tel
--
Fax
--
Country
India
ProdList
1185
Advantage
58
Brisben Chemicals
Tel
--
Fax
--
Country
India
ProdList
508
Advantage
58
Survival Technologies Pvt., Ltd. (STPL)
Tel
--
Fax
--
Email
info@survivaltechnologies.in
Country
India
ProdList
119
Advantage
58
Chemrich Fine Chemicals Pvt., Ltd.
Tel
--
Fax
--
Email
info@chemrichfine.com
Country
India
ProdList
399
Advantage
58
Arrow Fine Chemicals
Tel
--
Fax
--
Country
India
ProdList
45
Advantage
58
THINQ PHARMA-CRO LIMITED
Tel
--
Fax
--
Email
enquiry@thinqcro.com
Country
India
ProdList
13
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Scientific OEM
Tel
--
Fax
--
Email
neeraj@scientificoem.com
Country
India
ProdList
1994
Advantage
38
National Chemical Co.
Tel
--
Fax
--
Email
bijdeep@gmail.com
Country
India
ProdList
59
Advantage
58
Avra Synthesis Pvt Ltd
Tel
--
Fax
--
Email
info@avrasynthesis.com
Country
India
ProdList
1603
Advantage
30
Molecraft LifeSciences Pvt Ltd
Tel
--
Fax
--
Email
info@molecraft.com
Country
India
ProdList
757
Advantage
0
Ladder Fine Chemicals
Tel
--
Fax
--
Country
India
ProdList
24
Advantage
58
Sakshi Corporation
Tel
--
Fax
--
Country
India
ProdList
223
Advantage
58
P.C. Chem India
Tel
--
Fax
--
Country
India
ProdList
134
Advantage
58
Otto Chemie Private Limited
Tel
--
Fax
--
Country
India
ProdList
76
Advantage
58
Sagar Life Sciences Pvt. Ltd.
Tel
--
Fax
--
Country
India
ProdList
54
Advantage
58
GLR Innovations
Tel
--
Fax
--
Country
India
ProdList
93
Advantage
58
Ms Life Sciences
Tel
--
Fax
--
Country
India
ProdList
341
Advantage
58
Mole Pharma
Tel
--
Fax
--
Country
India
ProdList
4
Advantage
58
Central Drug House(P) Ltd.
Tel
--
Fax
--
Email
sales@cdhfinechemical.com
Country
India
ProdList
6157
Advantage
58
LOBA CHEMIE PVT.LTD.
Tel
--
Fax
--
Email
info@lobachemie.com
Country
India
ProdList
3075
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
Survival Technologies Pvt Ltd
Tel
--
Fax
--
Email
swami@survivaltechnologies.in
Country
India
ProdList
290
Advantage
50
More
Less

View Lastest Price from TEMPO manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2,2,6,6-Tetramethylpiperidinooxy 2564-83-2
Price
US $40.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-17
Jinan Finer Chemical Co., Ltd
Product
2,2,6,6-Tetramethylpiperidinooxy 2564-83-2
Price
US $12.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200mt/year
Release date
2022-12-14
Shaanxi Dideu Medichem Co. Ltd
Product
2,2,6,6-Tetramethylpiperidinooxy 2564-83-2
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
2000tons
Release date
2019-12-31

2564-83-2, TEMPORelated Search:

Haloperidol Benzoyl peroxide Triacetonediamine 2,2,6,6-Tetramethyl-4-piperidinol 1,2,2,6,6-Pentamethyl-4-piperidinol 2,2,6,6-Tetramethylpiperidine Triacetonamine 4-Hydroxy-2,2,6,6-tetramethylpiperidinooxy radical,4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxy Diphenoxylate 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-yl 4-Acetylamino-2,2,6,6-tetramethylpiperidin-N-oxyl,4-Acetamido-2,2,6,6-tetramethylpiperidinooxy,4-ACETYLAMINO-2,2,6,6-TETRAMETHYLPIPERIDIN-1-OXYL 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY, FREE RADICAL,4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY,4-Oxo-2,2,6,6-tetramethylpiperidinooxy, 95%, free radical 4-Amino-TEMPO, free radical 4-BENZOYLOXY-TEMPO [4-Methoxy-2,2,6,6-tetramethylpiperidinooxy]radical Tetrabutylammonium hydroxide 4-CYANO-TEMPO 4-(2-CHLOROACETAMIDO)-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL

  • 2,2,6,6-Tetramethyl-1-piperinedinyloxy
  • TEMPO, FREE RADICAL
  • TEMPO
  • 2,2,6,6-Tetramethyl-1-piperidyloxy
  • 2,2,6,6-Tetramethylpiperidin-1-oxy
  • 2,2',6,6'-Tetramethylpiperidin-1-oxyl
  • 2,2,6,6-Tetramethylpiperidin-1-oxyl
  • 2,2,6,6-Tetramethylpiperidine 1-oxide
  • 2,2,6,6-TETRAMETHYLPIPERIDINOOXY
  • 2,2,6,6-TETRAMETHYLPIPERIDINOOXY, FREE RADICAL
  • 2,2,6,6-TETRAMETHYL PIPERIDINOXY
  • 2,2,6,6-TETRAMETHYLPIPERIDINOXY FREE RADICAL
  • 2,2,6,6-TETRAMETHYLPIPERIDINYLOXY
  • 2,2,6,6-TETRAMETHYL-4-PIPERIDINYLOXY
  • 2,2,6,6-TETRAMETHYLPIPERIDIN-1-OXYL FREE RADICAL
  • 2,2,6,6-TETRAMETHYL-1-PIPERIDINOOXY
  • 2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY
  • 2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY,FREE RADICAL
  • 2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY, RADICAL
  • TETRABUTYLAMMONIUM HYDROXIDE 1.0M SOLN&
  • 2,2,6,6-Tetramethyl-1-Piperidinyloxy(Tempo)
  • 2,2,6,6-Tetramethyl-1-piperidinyloxiTEMPO
  • 2,2,6,6-Tetramethylpiperidine-1-oxyl(TEMPO,freeradical)
  • 1-Piperidinyloxy, 2,2,6,6-tetramethyl-
  • 2,2,6,6-TETRAMETHYLPIPERIDINOOXY (TEMPO)
  • 2,2,6,6-TETRAMETHYLPIPERIDINYLOXY / TEMPO, FREE RADICAL
  • 2,2,6,6-Tetramethylpiperidine-1-oxyl, free radical
  • TEMPO FREE RADICAL (2,2,6,6-TETRAMETHYLPIPERIDINOOXY)
  • 2,2,6,6-tetramethylpiperidinyloxy,free radical
  • 1-Oxy-2,2,6,6-tetramethylpiperidine, free radical
  • TEMPO, free radical, 98+%
  • TEMPO/2,2,6,6-TETRAMETHYLPIPERIDINOOXY
  • TEMPO,98%
  • 2,2,6,6-TETRAMETHYLPIPERIDIN-1-YLOXY
  • free radical, 2,2,6,6-Tetramethylpiperidine 1-oxyl
  • 2,2,6,6-Tetramethylpiperidine-1-oxyl (free radical) for synthesis
  • 1,1,5,5-Tetramethylpentamethylene nitroxide
  • 1-Oxyl-2,2,6,6-tetramethylpiperidine
  • 1-Piperidinyloxy radical, 2,2,6,6-tetramethyl-
  • 2,2,6,6-Tetramethyl-1-oxylpiperidine
  • 2,2,6,6-Tetramethyl-1-piperadoxyl
  • 2,2,6,6-Tetramethyl-1-piperidinoxyl
  • 2,2,6,6-tetramethyl-1-piperidinylox
  • TEMPO, free radica
  • 2,2,6,6-Tetramethyl-1-piperidinyloxyTEMPO. 2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical 2,2,6,6-Tetramethylpiperidine 1-oxyl
  • 2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical(purified by sublimation)
  • 2,2,6,6 - tetramethylpiperidine - nitrogen - oxide
  • TEMPO,2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical, 2,2,6,6-Tetramethylpiperidine 1-oxyl, TEMPO
  • 2,2,6,6-Tetramethylpiperidine 1-oxyl, free radical - solid melt
  • TEMPO Oxidation Agent
  • 2,2,6,6-Tetramethylpiperidine 1-oxyl, free radical - free flowing milled solid
  • 2,2,6,6-TetraMethylpiperidinooxy, 98% 5GR
  • 2,2,6,6-Tetramethylpiperidine N-oxide
  • 2,2,6,6-Tetramethylpiperidinooxy ,98%
  • (2,2,6,6-Tetramethylpiperidin-1-yloxy)radical
  • 2,2,6,6-Tetramethyl-4-piperidone,free radical
  • 2,2,6,6-tetramethylperidinooxy
  • Piperidinooxy, 2,2,6,6-tetramethyl-