ChemicalBook > CAS DataBase List > CCG215022

CCG215022

Product Name: CCG215022
CAS No.: 1813527-81-9
Chemical Name: CCG215022
Synonyms: CS-2782;CCG215022;CCG-215022 (CCG215022;CCG215022, 10 mM in DMSO;CCG215022;CCG-215022;CCG 215022;PKA,CCG215022,CCG-215022,Inhibitor,Protein kinase A,CCG 215022,inhibit;4-(4-Fluoro-3-((pyridin-2-ylmethyl)carbamoyl)phenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide;5-Pyrimidinecarboxamide, 4-[4-fluoro-3-[[(2-pyridinylmethyl)amino]carbonyl]phenyl]-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-
CBNumber: CB63146606
Molecular Formula: C26H22FN7O3
Formula Weight: 499.5
MOL File: 1813527-81-9.mol

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CCG215022 Property

Boiling point:: 783.2±60.0 °C(Predicted)
Density: 1.422±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 1 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
form: A crystalline solid
pka: 11.09±0.70(Predicted)
color: White to gray

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-5870
Product name: CCG215022
Purity: 98.33%
Packaging: 1mg
Price: $168
Updated: 2021/12/16

ChemScene

Product number: CS-5870
Product name: CCG215022
Purity: 98.33%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ChemScene

Product number: CS-5870
Product name: CCG215022
Purity: 98.33%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

Crysdot

Product number: CD00007453
Product name: CCG215022
Purity: 98+%
Packaging: 10mg
Price: $149
Updated: 2021/12/16

Ambeed

Product number: A152319
Product name: CCG-215022
Purity: 98+%
Packaging: 5mg
Price: $307
Updated: 2021/12/16

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CCG215022 Chemical Properties,Usage,Production

Uses

CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.

References

[1] Homan KT, et al. Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally DesignedInhibitor. J Biol Chem. 2015 Aug 21;290(34):20649-59. DOI:10.1074/jbc.M115.647370

CCG215022 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CCG215022 manufacturers

Career Henan Chemical Co

Product: CCG215022 1813527-81-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-01

1813527-81-9, CCG215022Related Search:

CCT128930 CC-122 CCT 137690 CC-92480 3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(2-furanyl)benzoyl]- CC-885 CCT245737 CCF-642

CCG215022

CS-2782

CCG215022;CCG-215022;CCG 215022

5-Pyrimidinecarboxamide, 4-[4-fluoro-3-[[(2-pyridinylmethyl)amino]carbonyl]phenyl]-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-

4-(4-Fluoro-3-((pyridin-2-ylmethyl)carbamoyl)phenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

PKA,CCG215022,CCG-215022,Inhibitor,Protein kinase A,CCG 215022,inhibit

CCG215022, 10 mM in DMSO

CCG-215022 (CCG215022

1813527-81-9