Methylprednisolone acetate

ChemicalBook > CAS DataBase List > Methylprednisolone acetate

Methylprednisolone acetate

Product Name: Methylprednisolone acetate
CAS No.: 53-36-1
Chemical Name: Methylprednisolone acetate
Synonyms: methylprednisolone 21-acetate;u8210;Mepred;NSC 48985;Vetacortyl;11-beta)-h;depo-medrone;Lumi-6αdepot-medrol;depo-medrate
CBNumber: CB6315522
Molecular Formula: C24H32O6
Formula Weight: 416.51
MOL File: 53-36-1.mol

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Methylprednisolone acetate Property

Melting point:: 192-195°C
alpha: D20 +101° (dioxane)
Boiling point:: 454.82°C (rough estimate)
Density: 1.1156 (rough estimate)
refractive index: 1.4593 (estimate)
storage temp.: Refrigerator
solubility: Practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent).
pka: 12.41±0.70(Predicted)
form: Solid
color: White to Off-White
optical activity: [α]/D 85 to 105°, c =0.5 in chloroform-d
CAS DataBase Reference: 53-36-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 63-62
Safety Statements: 36/37-24/25
HS Code: 32041200
Toxicity: LD50 oral in rat: > 10gm/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H361Suspected of damaging fertility or the unborn child
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR1718
Product name: Methylprednisolone acetate
Packaging: 500mg
Price: $114
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1436006
Product name: Methylprednisolone acetate
Packaging: 200mg
Price: $436
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001760
Product name: Methylprednisolone acetate for system suitability
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001760
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001736
Product name: Methylprednisolone acetate for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001736
Price: $153
Updated: 2024/03/01

Sigma-Aldrich

Product number: M1755000
Product name: Methylprednisolone acetate
Packaging: m1755000
Price: $220
Updated: 2024/03/01

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Methylprednisolone acetate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

6α-Methyl Prednisolone 21-Acetate is used as a glucocorticoid.

Uses

Methylprednisolone acetate is used as a glucocorticoid.

Definition

ChEBI: An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

brand name

Medrol (Pharmacia & Upjohn).

Biological Activity

Long-acting anti-inflammatory corticosteroid th at suppresses lymphocytes-mediated immunologic responses.

Methylprednisolone acetate (Depo-Medrol) is a long-acting anti-inflammatory corticosteroid th at suppresses lymphocytes-mediated immunologic responses. 6-Methylprednisolone acetate binds to intracellular glucocorticoid receptors and inhibits promoter domains of pro-inflammatory genes and hinders secretion of inflammatory cytokines. It effectively treats multiple ailments such as rheumatic and autoimmune diseases, leukemia, multiple myeloma, and Hodgkin's and non-Hodgkin's lymphoma symptoms along with other drugs. MPA improves COVID-19 pneumonia prognosis.

Toxics Screening Level

The initial threshold screening level (ITSL) for methylpredisolone acetate is 43 μg/m3 based on an annual averaging time.

Methylprednisolone acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methylprednisolone acetate manufacturers

Hebei Mujin Biotechnology Co.,Ltd

Product: Methylprednisolone acetate 53-36-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-05-19

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Methylprednisolone acetate 53-36-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99% min
Supply Ability: 20 tons
Release date: 2022-12-05

Hangzhou Huarong Pharm Co., Ltd.

Product: Methylprednisolone Acetate 53-36-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KG
Release date: 2021-09-14

53-36-1, Methylprednisolone acetateRelated Search:

Prednisolone Ammonium acetate Medroxyprogesterone Acetate Vinyl acetate 1-Methoxy-2-propyl acetate Glatiramer acetate Sodium acetate Prednisolone-21-acetate Methylprednisolone aceponate 6alpha-Methylprednisolone sodium succinate POLY(VINYL ACETATE) Ethyl acetate Cellulose acetate Methylprednisolone hemisuccinate Methylprednisolone ACETATE 9alpha-Fluoro-16alpha-methylprednisolone acetate Methylprednisolone Acetate, Micronized

depo-medrone

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-

METHYLPREDNISOLONEACETATE,MICRONIZED,USP

21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione

6a-Methylprednisolone 21-acetate

DepMedalone 40

DepMedalone 80

Mepred

NSC 48985

Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-6a-methyl-, 21-acetate (6CI, 7CI, 8CI)

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6a,11b)- (9CI)

Vetacortyl

Methylprednisolone Acetate BP/USP/EP

21-Acetoxy-11,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione

[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate

acetic acid [2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-3-keto-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester

6α-Methyl Prednisolone 21-Acetate

Methylprednisolone Acetate (200 mg)

Methylprednisolone a

21-Acetoxy-11β,17-dihydroxy-6α-Methylpregna-1,4-diene-3,20-dione

6-alpha-methylprednisolone21-acetate

Lumi-6&alpha

Methylprednisolone Hydrogen Succinate EP Impurity C

Methylprednisolone acetate for peak identification

Methylprednisolone acetate for system suitability

Methylprednisolone EP Impurity J(Methylprednisolone Acetate)

depo-methylprednisolone

depo-methylprednisoloneacetate

depot-medrol

u8210

urbasoncrystalsuspension

2-((6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate

methylprednisolone 21-acetate

METHYLPREDNISOLONE ACETATE

MEDROL ACETATE

depo-medrate

1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-ACETATE

1,4-PREGNADIEN-6-ALPHA-METHYL-17,21-DIOL-3,11,20-TRIONE ACETATE

6-ALPHA-METHYLPREDNISOLONE ACETATE

6-ALPHA-METHYLPREDNISONE ACETATE

6-METHYL PREDNISOLONE ACETATE

11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate

Methylprednisolone Acetate Api

11-beta)-h

4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-aceta

4-diene-3,20-dione,21-(acetyloxy)-11,17-dihydroxy-6-methyl-pregna-(6-alp

Methylprednisolone Impurity 9(Methylprednisolone EP Impurity J)

Methylprednisolone EP Impurity J

Methylprednisolone acetate for peak identification CRS

Methylprednisolone acetate CRS

Methylprednisolone EP Impurity J(Methylprednisolone Acetate,Methylprednisolone Hydrogen Succinate EPImpurity C)

Methylprednisolone 21-acetate Solution in Acetonitrile，1000μg/mL

11beta,17-Dihydroxy-6alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl Acetate

Methylprednisolone acetate USP/EP/BP

Methylprednisolone Acetate (1436006)

5-Diiodo-L-tyrosine dihydrate

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6α,11β)-