5-Fluoro-2-nitrobenzadehyde
- Product Name
- 5-Fluoro-2-nitrobenzadehyde
- CAS No.
- 395-81-3
- Chemical Name
- 5-Fluoro-2-nitrobenzadehyde
- Synonyms
- 5-FLUORO-2-NITROBENZALDEHYDE;KML-73;KML-105;uoro-2-nitrobenzaL;5-Fluoro-2-nitrobenzadehyde;2-NITRO-5-FLUOROBENZALDEHYDE;5-Fluoro-2-nitrobenzladehyde;4-Fluoro-2-formylnitrobenzene;4-Chloro-5'-fluorobenzophenone;5-Fluoro-2-nitrobenzaldehyde>
- CBNumber
- CB6317142
- Molecular Formula
- C7H4FNO3
- Formula Weight
- 169.11
- MOL File
- 395-81-3.mol
5-Fluoro-2-nitrobenzadehyde Property
- Melting point:
- 92-94°C
- Boiling point:
- 153°C 23mm
- Density
- 1.443±0.06 g/cm3(Predicted)
- Flash point:
- >110°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Water Solubility
- Insoluble in water
- form
- powder to crystal
- color
- White to Light red to Green
- Sensitive
- Air Sensitive
- BRN
- 1869010
- InChI
- InChI=1S/C7H4FNO3/c8-6-1-2-7(9(11)12)5(3-6)4-10/h1-4H
- InChIKey
- KKAFVHUJZPVWND-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC(F)=CC=C1[N+]([O-])=O
- CAS DataBase Reference
- 395-81-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F0645
- Product name
- 5-Fluoro-2-nitrobenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $46
- Updated
- 2025/07/31
- Product number
- F0645
- Product name
- 5-Fluoro-2-nitrobenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $169
- Updated
- 2025/07/31
- Product number
- 37972
- Product name
- 5-Fluoro-2-nitrobenzaldehyde
- Purity
- 98%
- Packaging
- 5G
- Price
- $313
- Updated
- 2021/12/16
- Product number
- PC3885D
- Product name
- 5-Fluoro-2-nitrobenzaldehyde
- Purity
- 98%
- Packaging
- 250g
- Price
- $325
- Updated
- 2021/12/16
- Product number
- 4654-3-72
- Product name
- 5-Fluoro-2-nitrobenzaldehyde
- Purity
- 97%
- Packaging
- 250g
- Price
- $359
- Updated
- 2021/12/16
5-Fluoro-2-nitrobenzadehyde Chemical Properties,Usage,Production
Chemical Properties
5-Fluoro-2-nitrobenzaldehyde is a very light yellow-light reddish yellow solid at room temperature and pressure, it is easily oxidized to form white benzoic acid products, and needs to be stored at low temperature.
Uses
5-Fluoro-2-nitrobenzaldehyde can be used as an intermediate in pharmaceutical chemistry and organic synthesis, and is used to prepare herbicides, plant growth regulators, etc.
Synthesis
287121-32-8
395-81-3
General procedure for the synthesis of 5-fluoro-2-nitrobenzaldehyde from 5-fluoro-2-nitrobenzyl alcohol: 5-fluoro-2-nitrobenzyl alcohol (13.92 g, 81.08 mmol) was dissolved in dichloromethane (284 mL). To the solution was added 4?molecular sieves (73 g) and pyridinium dichromate (36.58 g, 97.3 mmol). The reaction mixture was stirred at 20 °C for 6 hours. After completion of the reaction, the crude reaction mixture was filtered through a short silica gel column. The filtrate was concentrated under reduced pressure to remove the solvent and the residue was purified by fast column chromatography (silica gel, 10-20% ethyl acetate/hexane as eluent) to afford 9.43 g (69% yield) of the target compound 5-fluoro-2-nitrobenzaldehyde as a colorless oil.1H-NMR (CDCl3) data: δ 10.44 (d, 1H), 8.22 (dd, 1H) , 7.62 (dd, 1H), 7.41 (ddd, 1H).
References
[1] Journal of Medicinal Chemistry, 2004, vol. 47, # 16, p. 3934 - 3937
[2] Patent: WO2003/76442, 2003, A1. Location in patent: Page/Page column 65
5-Fluoro-2-nitrobenzadehyde Preparation Products And Raw materials
Raw materials
Preparation Products
5-Fluoro-2-nitrobenzadehyde Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 5-Fluoro-2-nitrobenzadehyde manufacturers
- Product
- 5-Fluoro-2-nitrobenzaldehyde 395-81-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.3%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21
- Product
- 5-Fluoro-2-nitrobenzadehyde 395-81-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-Fluoro-2-nitrobenzadehyde 395-81-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09