(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Product Name: (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS No.: 125971-94-0
Chemical Name: (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms: ATS-8;(4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8);tert-Butyl 2-((4R,6R)-6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate;(4R,6R)-tert-Butyl-6;Atorvastatin Impurity 7;Atorvastatin calcium-11;Ats-8(For Atorvastatin);Atorvastatin Impurity 63;(4R,6R)-Tert-Butyl-6-Cyanometh
CBNumber: CB6327897
Molecular Formula: C14H23NO4
Formula Weight: 269.34
MOL File: 125971-94-0.mol

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(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Property

Melting point:: 65-69 °C(lit.)
Boiling point:: 364.1±17.0 °C(Predicted)
Density: 1.016±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: soluble in Chloroform
form: powder to crystal
color: White to Almost white
optical activity: [α]20/D 1.0°, c = 1 in chloroform
CAS DataBase Reference: 125971-94-0(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 539015
Product name: tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Purity: 97%
Packaging: 1g
Price: $48.4
Updated: 2024/03/01

TCI Chemical

Product number: B3642
Product name: tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Purity: >98.0%(GC)(N)
Packaging: 5g
Price: $85
Updated: 2024/03/01

TRC

Product number: C982020
Product name: (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster
Packaging: 500mg
Price: $110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0000262
Product name: (4R -CIS)-1, 1-DIMETHYLETHYL -6- CYANOMETHYL-2, 2-DIMETHYL-1, 3-DIOXANE-4-ACETATE
Purity: 95.00%
Packaging: 1G
Price: $123.9
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB32752
Product name: (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Packaging: 25g
Price: $400
Updated: 2021/12/16

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(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Atorvastatin Intermediate

Uses

(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Suppliers

Americas 1 Belgium 2 Canada 2 China 258 Europe 3 Germany 4 India 46 Japan 2 South Korea 2 Switzerland 2 United Kingdom 7 United States 32 Global 361

Jiangsu WNC Pharmaceutical Co.,Ltd

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JIANGXI AIFEIMU TECHNOLOGY CO.,LTD

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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View Lastest Price from (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 125971-94-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-07

hebei hongtan Biotechnology Co., Ltd

Product: (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 125971-94-0
Price: US $80.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-03-22

R&D Scientific Inc.

Product: (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester 125971-94-0
Price: US $786.00/Kg
Min. Order: 0.100Kg
Purity: 99 %
Supply Ability: 5000 Kg
Release date: 2024-11-20

125971-94-0, (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetateRelated Search:

Dimethyl fumarate Dimethyl sulfoxide Isobutyl acetate tert-Butanol tert-Butyl chloroacetate tert-Butyl acetate Dimethylbenzylcarbinyl acetate tert-Butyl bromoacetate N,N-Dimethylformamide DL-sec-Butyl acetate Methyl 2,2-dimethylphenylacetate Butyl acetate tert-Butyl peroxyacetate ETHANE (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Atorvastatin calcium Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Atorvastatin

ATS-8

(4R,6R)-T-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE

(4R,6R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE

(4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE

(4R,3R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE

(4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8)

tert-Butyl (4R,3R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXAN-4-YL]ACETATE

(4R,6R)-t-butyl-6-cyanomethyl02,2-dimethyl-1,3-dioxane-4-acetate

(4R-cis)-1,1-dimethylethyl-6-cyanomethyl -2,2-dimethyl-1,3-dloxane-4-acetate

(4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester

tert-Butyl 2-((4R,6R)-6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate

1,3-Dioxane-4-aceticacid, 6-(cyanoMethyl)-2,2-diMethyl-, 1,1-diMethylethyl ester, (4R,6R)-

tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 97%

tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Atorvastatin intermediatesAts-8

(4R-Cis)-l,l-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Aceta

Atorvastatin Impurity 7

Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6R)-Isomer

4R CIS)-1.1-DIMETHYLETHYL-6-CYANOMETHYL- 2 2-DIMETHYL-1 3-DIOXANE-4-ACETAT

Atorvastatin Impurity 63

2-[6-(bromomethyl)-1,3-dioxan-4-yl]-3,3-dimethylbutanoate

Atorvastatin Calcium Hydrate impurity 19

Atorvastatin calcium-11

Ats-8:(4R,Cis)-1,1-Dimethylethyl-Cyanomethyl-2,2-Dimethyl

(4R)-cis-6-1,1-Dimethyl-6-cyanomethyl-2-2-dimethyl-1,3-dioaneacetate

Intermediateofatorvastatinecalcium(CAS#134523-03-8)

1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-1,1-dimethylethylester

TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-1,3-DIOXAN-4-YL]ACETATE

(4R,6R)-t-Butyl-6-AMINOMETHYL-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-Tert-Butyl-6-Cyanometh

ATS 8 (4R,CIS)-1,1-DIMETHYLETHY-L-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE

ATS-8:(4R-CIS)-T-ETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,2-DIMETHYL-1,2-DIONMANO 1 ACETATE

(4R-Cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dio-cxane-4-acetate

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate,97%

Tert-Butyl(3R,5R)-6-cyano-3,5-O-iso-propylidene-3,5-dihydroxyhexanoate

(4R,6R)-tert-Butyl-6

(4R-Cis)-1,1-diMethylethyl-6-Cyanoethyl-2,2-diMethyl-1,3-dioxane-4-acetate

ATS-8 (4R, cis)C1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane C4-Acetate

Tetr-butyl[(4R,6R)-6-cyanomethyl-1,3-dioxan-4-yl]acetate

tert-Butyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxolane-4-acetate

tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

2-[6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl]-3,3-diMethylbutanoate

Ats-8(For Atorvastatin)

((4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester

tert-Butyl(4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate&gt

(4R,6R)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane- 4-acetate(A8)

(4R-cis)-6-1,1-Dimethyl-6-cyanomethly-2-2-dimethly-1,3-dioane-acetate

(4r-Cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Di...

1,1-Dimethylethyl 2-[(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

tert-Butyl 2-((4R,6R)-6-cyanomethyl-2,2- dimethyl-1,3-dioxane-4-yl)acetate

1,1-Dimethylethyl (4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

(4r,6r)-tert-butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)

Atorvastatin calcium impurity 19

(4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)

ATS-8（Intermediate of Atorvastatin)

125971-94-0