ChemicalBook > CAS DataBase List > 2,6-DIAMINO-4-METHOXY PYRIMIDINE

2,6-DIAMINO-4-METHOXY PYRIMIDINE

Product Name: 2,6-DIAMINO-4-METHOXY PYRIMIDINE
CAS No.: 3270-97-1
Chemical Name: 2,6-DIAMINO-4-METHOXY PYRIMIDINE
Synonyms: Minoxidil Impurity 41;Minoxidil Impurity 13;2,4-Diamino-6-methoxypyrimidine;2,6-DIAMINO-4-METHOXY PYRIMIDINE;6-methoxy-pyrimidine-2,4-diamine;2,4-Pyrimidinediamine, 6-methoxy-;2-AMINO-6-METHOXYPYRIMIDIN-4-YLAMINE;2,6-Diamino-4-methoxy pyrimidine ,97%;2,4-Pyrimidinediamine, 6-methoxy- (9CI);2,6-DIAMINO-4-METHOXY PYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB6344559
Molecular Formula: C5H8N4O
Formula Weight: 140.14
MOL File: 3270-97-1.mol

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2,6-DIAMINO-4-METHOXY PYRIMIDINE Property

Melting point:: 162.0 to 166.0 °C
Boiling point:: 429.4±48.0 °C(Predicted)
Density: 1.341±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 5.24±0.10(Predicted)
color: White to Almost white
λmax: 265nm(MeOH)(lit.)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D5088
Product name: 2,4-Diamino-6-methoxypyrimidine
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $149
Updated: 2025/07/31

TCI Chemical

Product number: D5088
Product name: 2,4-Diamino-6-methoxypyrimidine
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $445
Updated: 2025/07/31

AK Scientific

Product number: Y4940
Product name: 2,6-Diamino-4-methoxypyrimidine
Packaging: 10g
Price: $523
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD147833
Product name: 2,6-Diamino-4-methoxypyrimidine
Packaging: 2g
Price: $523
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK102173
Product name: 2,6-Diamino-4-methoxypyrimidine
Purity: 97%
Packaging: 5g
Price: $656
Updated: 2021/12/16

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2,6-DIAMINO-4-METHOXY PYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

2,4-Diamino-6-methoxypyrimidine is an organic amine compound used as a raw material for organic synthesis or as a pharmaceutical intermediate ingredient. The product can be used to prepare other heterocyclic compounds or anticancer active ingredients.

Synthesis

67-56-1

156-83-2

3270-97-1

General procedure for the synthesis of 2,4-diamino-6-methoxypyrimidine from methanol and 2,4-diamino-6-chloropyrimidine: 9.2 g (0.40 mol) of sodium metal was added to a flask containing 320 mL of methanol and stirred until completely dissolved. Subsequently, 28.9 g (0.20 mol) of 2,4-diamino-6-chloropyrimidine was added to this solution. The reaction mixture was placed under reflux conditions and stirred continuously for 44 hours. Upon completion of the reaction, the precipitated sodium chloride was removed by filtration. The filtrate was concentrated to dryness to give the crude product. The crude product was dissolved in 300 mL of ethanol, heated to boiling and then thermally filtered. The filtrate was allowed to stand overnight to crystallize 2,4-diamino-6-methoxypyrimidine. The product can be further purified by recrystallization of the mother liquor. After drying, 2,4-diamino-6-methoxypyrimidine (58.8 g, 84% yield) was obtained as a white solid. Melting point: 166-169 °C. 1H-NMR (300 MHz, d6-DMSO): δ= 3.18 (s, 3H, 6-OMe), 5.06 (s, 1H, 5-H), 5.94 (s, 2H, NH2), 6.05 (s, 2H, NH2). 13C-NMR (125 MHz, d6-DMSO): δ= 52.8 ( 6-OMe), 76.1 (5-C), 163.3 (2-C), 166.3 (4-C), 170.8 (6-C).

References

[1] Organic and Biomolecular Chemistry, 2010, vol. 8, # 10, p. 2397 - 2407
[2] Patent: US2015/209257, 2015, A1. Location in patent: Paragraph 0239; 0240; 0241; 0242; 0243
[3] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 917 - 921

2,6-DIAMINO-4-METHOXY PYRIMIDINE Preparation Products And Raw materials

Raw materials

2,4-Diamino-6-hydroxypyrimidine Toluene Sodium Phosphorus oxitrichloride Methanol Sodium carbonate

Preparation Products

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View Lastest Price from 2,6-DIAMINO-4-METHOXY PYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2,6-DIAMINO-4-METHOXY PYRIMIDINE 3270-97-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-15

Career Henan Chemical Co

Product: 2,6-DIAMINO-4-METHOXY PYRIMIDINE 3270-97-1
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

3270-97-1, 2,6-DIAMINO-4-METHOXY PYRIMIDINERelated Search:

2,6-DIAMINO-4-METHOXY PYRIMIDINE 2,4-DIAMINO-6-ETHOXYPYRIMIDINE 2,3-Diamino-6-methoxypyridine Pyrimidine 6-Benzyloxy-5-nitroso-pyrimidine-2,4-diamine 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE CHEMPACIFIC 39933 N-[2-(DIMETHYLAMINO)-6-METHOXYPYRIMIDIN-4-YL]ACETAMIDE N-(2-AMINO-6-METHOXY-5-NITROSOPYRIMIDIN-4-YL)-N-METHYLAMINE 2,4-DIAMINO-5-(NITRO)-6-(METHYLOXY)PYRIMIDINE 2-AMINO-6-(2,4-DICHLOROPHENOXY)PYRIMIDIN-4-YLAMINE 2-AMINO-4-METHOXY-6-MORPHOLIN-4-YLPYRIMIDINE-5-CARBALDEHYDE 2-AMINO-4-METHOXY-6-PYRROLIDIN-1-YLPYRIMIDINE-5-CARBALDEHYDE N-[2-(ACETYLAMINO)-6-METHOXY-4-PYRIMIDINYL]ACETAMIDE N-[4-AMINO-5-NITROSO-6-(PENTYLOXY)PYRIMIDIN-2-YL]-N-METHYLAMINE N-(2-AMINO-6-METHOXY-5-NITROSOPYRIMIDIN-4-YL)THIOPHENE-2-CARBOXAMIDE 2,4-diamino-6-(benzyloxy)pyrimidine-5-carbonitrile 4-AMINO-2-(DIMETHYLAMINO)-5-(NITRO)-6-(METHYLOXY)PYRIMIDINE

2,6-DIAMINO-4-METHOXY PYRIMIDINE

2-AMINO-6-METHOXYPYRIMIDIN-4-YLAMINE

2,4-Pyrimidinediamine, 6-methoxy- (9CI)

2,6-Diamino-4-methoxy pyrimidine ,97%

2,4-Diamino-6-methoxypyrimidine

6-methoxy-pyrimidine-2,4-diamine

2,4-Pyrimidinediamine, 6-methoxy-

2,6-DIAMINO-4-METHOXY PYRIMIDINE ISO 9001：2015 REACH

Minoxidil Impurity 13

Minoxidil Impurity 41

3270-97-1

36315-02-1

PYRIMIDINE