ChemicalBook > CAS DataBase List > Maleimide

Maleimide

Product Name
Maleimide
CAS No.
541-59-3
Chemical Name
Maleimide
Synonyms
1h-pyrrole-2,5-dione;Maleic imide;PYRROLE-2,5-DIONE;Maleinimide;MALEIC ACID IMIDE;MaleiMide, 98% 10GR;NSC 13684;MALEIMIDE;maleicimide;Maleimide>
CBNumber
CB6358686
Molecular Formula
C4H3NO2
Formula Weight
97.07
MOL File
541-59-3.mol
More
Less

Maleimide Property

Melting point:
91-93 °C (lit.)
Boiling point:
97-103°C 5mm
Density 
1,2493 g/cm3
refractive index 
1.4543 (estimate)
Flash point:
97-103°C/5mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
pka
8.52±0.20(Predicted)
form 
Fine Crystalline Powder
color 
White to slightly yellow
Water Solubility 
SOLUBLE
λmax
280nm(EtOH)(lit.)
BRN 
106910
InChIKey
PEEHTFAAVSWFBL-UHFFFAOYSA-N
CAS DataBase Reference
541-59-3(CAS DataBase Reference)
NIST Chemistry Reference
1H-pyrrole-2,5-dione(541-59-3)
EPA Substance Registry System
1H-Pyrrole-2,5-dione (541-59-3)
More
Less

Safety

Hazard Codes 
T,C
Risk Statements 
25-34-43-36/37/38-36
Safety Statements 
26-36/37/39-45-37/39-28A-7/9
RIDADR 
UN 2923 8/PG 2
WGK Germany 
3
RTECS 
ON4800000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129585
Product name
Maleimide
Purity
99%
Packaging
2g
Price
$40.4
Updated
2024/03/01
Sigma-Aldrich
Product number
129585
Product name
Maleimide
Purity
99%
Packaging
10g
Price
$118
Updated
2024/03/01
TCI Chemical
Product number
M0018
Product name
Maleimide
Purity
>98.0%(T)
Packaging
5g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
M0018
Product name
Maleimide
Purity
>98.0%(T)
Packaging
25g
Price
$190
Updated
2024/03/01
Alfa Aesar
Product number
A13135
Product name
Maleimide, 98+%
Packaging
5g
Price
$58.8
Updated
2024/03/01
More
Less

Maleimide Chemical Properties,Usage,Production

Chemical Properties

slight yellow crystalline powder

Uses

Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.

Uses

Rhodium-catalyzed conjugate arylation with arylboronic acids.1

Definition

ChEBI: A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure.

General Description

Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.

Hazard

A poison.

Safety Profile

Poison by intraperitoneal and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify it by sublimation in a vacuum. The UV has max at 216 and 280nm in EtOH. [de Wolf & van de Straete Bull Soc Chim Belg 44 288 1935, UV: Rondestvedt et al. J Am Chem Soc 78 6115 1956, IR: Chiorboli & Mirone Ann Chim (Rome) 42 681 1952, Beilstein 21/10 V 3.]

Maleimide Preparation Products And Raw materials

Raw materials

Potassium dichromate Fiber Glass Wool

Preparation Products

N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA 4-MALEIMIDOBUTYRIC ACID N-METHOXYCARBONYLMALEIMIDE
More
Less

Maleimide Suppliers

Americas 1 Austria 1 Belgium 1 Canada 2 China 313 Europe 3 France 1 Germany 5 India 8 Japan 5 Poland 1 Slovakia 3 Switzerland 3 United Kingdom 17 United States 46 Global 410
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Monomer Polymer & Dajac Labs
Tel
--
Fax
--
Email
info@monomerpolymer.com
Country
United States
ProdList
1609
Advantage
58
SynQuest Laboratories, Inc.,
Tel
--
Fax
--
Country
United States
ProdList
2301
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Barath Biosciences, Inc.
Tel
--
Fax
--
Email
barath@barathbiosciences.com
Country
United States
ProdList
203
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
AstaTech, Inc
Tel
--
Fax
--
Email
sales@astatechinc.com
Country
United States
ProdList
6371
Advantage
58
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
BIOMOL INTERNATIONAL, LP
Tel
--
Fax
--
Email
info@biomol.com
Country
United States
ProdList
1499
Advantage
77
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Monomer-Polymer & Dajac Laboratories, Inc.
Tel
--
Fax
--
Email
monomerpolymer@comcast.net
Country
United States
ProdList
1989
Advantage
60
AsisChem, Inc.
Tel
--
Fax
--
Email
support@asischem.com
Country
United States
ProdList
4101
Advantage
55
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
More
Less

View Lastest Price from Maleimide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Maleimide 541-59-3
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-10
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Maleimide 541-59-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.0%
Supply Ability
1kg/month
Release date
2023-02-13
Hebei Weibang Biotechnology Co., Ltd
Product
Maleimide 541-59-3
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-10-25

541-59-3, MaleimideRelated Search:

O-Phthalimide Pyrrole N-Benzylmaleimide CIS-BUTENEDIOIC ANHYDRIDE Maleic acid Monobutyl maleate Succinimide alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol) Mal-Amido-PEG4-acid Maleimide-PEG2-NHS Ester Mal-PEG8-COOH Maleamic acid Polyamideimide N,N'-1,3-Phenylene bismaleimide N-Phenylmaleimide DIALIFOS N-Cyclohexylmaleimide Bismaleimide

  • MaleiMide, 98% 10GR
  • MaleiMide, 98% 25GR
  • 2,5-Dioxo-2,5-dihydropyrrole
  • NSC 13684
  • 1H-Pyrrole-2,5-dione, 2,5-Dihydro-2,5-dioxo-1H-pyrrole
  • MaleiMide 99%
  • 5-hydroxy-2H-pyrrol-2-one
  • PYRROLE-2,5-DIONE
  • 2,5-Dioxo-3-pyrroline~1H-Pyrrole-2,5-dione
  • 3-Pyrroline-2,5-dione
  • Maleic imide
  • maleicimide
  • Maleinimide
  • MALEIMIDE
  • MALEIC ACID IMIDE
  • ASISCHEM S97810
  • 1h-pyrrole-2,5-dione
  • 2,5-PYRROLEDIONE
  • Maleimide, 98+%
  • 2,5-dioxo-3-pyrroline
  • 1H-Pyrrole-2,5-dione,2,5-Pyrroledione
  • Maleimide,90-95%
  • Maleimide&gt
  • Maleimide, 98%, for synthesis
  • potassium silver(1+) bis(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-ide)
  • Maleinseureimid
  • 541-59-3
  • 41-59-3
  • AMINE
  • Cyclic Imides
  • Organic Building Blocks
  • Carbonyl Compounds
  • Building Blocks
  • Miscellaneous Reagents
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Cyclic Imides
  • Organic Building Blocks
  • MTS & Sulfhydryl Active Reagents
  • Heterocycles series
  • Heterocycles