4-HYDROXY-6-METHYLQUINAZOLINE

Product Name: 4-HYDROXY-6-METHYLQUINAZOLINE
CAS No.: 19181-53-4
Chemical Name: 4-HYDROXY-6-METHYLQUINAZOLINE
Synonyms: BUTTPARK 51\07-11;6-methylquinazolin-4-ol;6-methyl-4-quinazolinol;6-methyl-4-quinazolinone;6-Methyl-4(3H)-quinazolinone;6-methyl-1H-quinazolin-4-one;6-methyl-3H-quinazolin-4-one;4-HYDROXY-6-METHYLQUINAZOLINE;4(3H)-Quinazolinone, 6-methyl-;6-Methylquinazolin-4(3H)-one98%
CBNumber: CB6360108
Molecular Formula: C9H8N2O
Formula Weight: 160.17
MOL File: 19181-53-4.mol

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4-HYDROXY-6-METHYLQUINAZOLINE Property

Melting point:: 238-240
Boiling point:: 334.6±35.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.06±0.20(Predicted)
Appearance: White to off-white Solid

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M356168
Product name: 6-methylquinazolin-4-ol
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M356168
Product name: 6-methylquinazolin-4-ol
Packaging: 50mg
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H17-1-67
Product name: 6-Methylquinazolin-4(3H)-one
Purity: 98%
Packaging: 1g
Price: $64
Updated: 2021/12/16

AK Scientific

Product number: Z4348
Product name: 6-Methylquinazolin-4-ol
Packaging: 250mg
Price: $72
Updated: 2021/12/16

Apolloscientific

Product number: OR2839
Product name: 4-Hydroxy-6-methylquinazoline
Purity: 97%
Packaging: 250mg
Price: $22
Updated: 2021/12/16

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4-HYDROXY-6-METHYLQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

40545-33-3

149-73-5

19181-53-4

Concentrated hydrochloric acid (4.16 mL, 49.9 mmol) was slowly added to a mixed solution containing commercially available 2-amino-5-methylbenzamide (5.00 g, 33.3 mmol) and trimethyl orthoformate (51.0 mL, 466 mmol) at 0 °C. The reaction mixture was stirred continuously for 2 hours at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue obtained was diluted with distilled water and neutralized with 2 M aqueous sodium hydroxide solution to neutral. Subsequently, the precipitated solid product was collected by filtration and washed sequentially with distilled water, methanol, and ether to finally obtain 6-methyl-4-hydroxyquinazoline (15) as a white powdery solid (4.33 g, 81% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 2.44 (3H, s), 7.57 (1H, d, J = 8.4 Hz), 7.62-7.66 (1H, m), 7.91-7.93 (1H, m), 8.03 (1H, s), 12.2 (1H, bs).

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 19, p. 5487 - 5505
[2] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 4, p. 545 - 548
[3] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 3, p. 383 - 391

4-HYDROXY-6-METHYLQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXY-6-METHYLQUINAZOLINE Suppliers

China 92 India 1 United Kingdom 3 United States 9 Global 105

J & K SCIENTIFIC LTD.

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Energy Chemical

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Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.

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View Lastest Price from 4-HYDROXY-6-METHYLQUINAZOLINE manufacturers

Career Henan Chemical Co

Product: 4-HYDROXY-6-METHYLQUINAZOLINE 19181-53-4
Price: US $3.00/KG
Min. Order: 1KG
Purity: 90%-99.9%
Supply Ability: 1000kg
Release date: 2019-07-04

19181-53-4, 4-HYDROXY-6-METHYLQUINAZOLINERelated Search:

Nolatrexed dihydrochloride 2,6-DIMETHYLQUINAZOLIN-4(3H)-ONE 4-HYDROXY-6-METHYLQUINAZOLINE 2-AMINO-6-METHYL-4(3H)-QUINAZOLONE Raltitrexed 8-METHYL-4-QUINAZOLONE 4-Hydroxy-2-methylquinazoline 8-Chloro-2-methylquinazolin-4(3H)-one NU1025 6-Quinazolinecarboxylic acid, 3,4-dihydro-3-(2-chlorophenyl)-5,7-dimet hyl-2-((((methylamino)carbonyl)oxy)methyl)-4-oxo-, ethyl ester (6-METHYL-4-OXO-3,4-DIHYDRO-QUINAZOLIN-2-YLSULFANYL)-ACETIC ACID Doqualast 3-(2,4-DICHLORO-5-METHOXYPHENYL)-6-METHYL-2-SULFANYL-4(3H)-QUINAZOLINONE (3-ETHYL-6-METHYL-4-OXO-3,4-DIHYDRO-QUINAZOLIN-2-YLSULFANYL)-ACETIC ACID 3-amino-2-(4-chlorophenyl)-6-methyl-4(3H)-quinazolinone (3-ALLYL-6-METHYL-4-OXO-3,4-DIHYDRO-QUINAZOLIN-2-YLSULFANYL)-ACETIC ACID 3-(4-FLUOROPHENYL)-2,6-DIMETHYL-4(3H)-QUINAZOLINONE (6-METHYL-4-OXO-3-PHENYL-3,4-DIHYDRO-QUINAZOLIN-2-YLSULFANYL)-ACETIC ACID

4-HYDROXY-6-METHYLQUINAZOLINE

BUTTPARK 51\07-11

3,4-Dihydro-6-methyl-4-oxoquinazoline

3,4-Dihydro-6-methyl-4-oxoquinazoline 98%

4-Hydroxy-6-methylquinazoline 97%

4-Hydroxy-6-methylquinazoline97%

6-methyl-4-quinazolinone

6-methylquinazolin-4-ol

6-Methylquinazolin-4(3H)-one 98%

6-Methyl-4(3H)-quinazolinone

6-Methylquinazolin-4-ol, 6-Methylquinazolin-4(3H)-one

6-Methylquinazolin-4(3H)-one98%

6-methyl-1H-quinazolin-4-one

4(3H)-Quinazolinone, 6-methyl-

4-HYDROXY-6-METHYLQUINAZOLINE ISO 9001：2015 REACH

6-methyl-3H-quinazolin-4-one

6-methyl-4-quinazolinol

19181-53-4

blocks

Heterocycles

Quinolines