4-Aminophenylacetic acid

ChemicalBook > CAS DataBase List > 4-Aminophenylacetic acid

4-Aminophenylacetic acid

Product Name: 4-Aminophenylacetic acid
CAS No.: 1197-55-3
Chemical Name: 4-Aminophenylacetic acid
Synonyms: 2-(4-AMINOPHENYL)ACETIC ACID;H-4-APH-OH;P-AMINOPHENYLACETIC ACID;NSC 7929;H-APH(4)-OH;4-AMino acid;p-Amino-alph;AKOS BBS-00006880;Desacetyl Actarit;Phenylglycine base
CBNumber: CB6373122
Molecular Formula: C8H9NO2
Formula Weight: 151.16
MOL File: 1197-55-3.mol

Less

4-Aminophenylacetic acid Property

Melting point:: 201 °C (dec.) (lit.)
Boiling point:: 273.17°C (rough estimate)
Density: 1.2023 (rough estimate)
refractive index: 1.5635 (rough estimate)
Flash point:: 201°C
storage temp.: Store below +30°C.
pka: pK1: 3.60;pK2: 5.26 (20°C)
form: Powder
color: Light yellow to beige
Water Solubility: Very soluble in water.
Decomposition: 201 ºC
Merck: 14,463
BRN: 2208094
LogP: 0.220 (est)
CAS DataBase Reference: 1197-55-3(CAS DataBase Reference)
NIST Chemistry Reference: Benzeneacetic acid, 4-amino-(1197-55-3)
EPA Substance Registry System: Benzeneacetic acid, 4-amino- (1197-55-3)

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: AF3550000
F: 13
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29224995
Toxicity: mouse,LD50,intraperitoneal,3500mg/kg (3500mg/kg),Farmaco, Edizione Scientifica. Vol. 13, Pg. 286, 1958.

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A71352
Product name: 4-Aminophenylacetic acid
Purity: 98%
Packaging: 25g
Price: $88.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: A71352
Product name: 4-Aminophenylacetic acid
Purity: 98%
Packaging: 100g
Price: $303
Updated: 2023/06/20

TCI Chemical

Product number: A0393
Product name: 4-Aminophenylacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $100
Updated: 2024/03/01

Alfa Aesar

Product number: A14675
Product name: 4-Aminophenylacetic acid, 98%
Packaging: 10g
Price: $32.65
Updated: 2024/03/01

Alfa Aesar

Product number: A14675
Product name: 4-Aminophenylacetic acid, 98%
Packaging: 50g
Price: $114.65
Updated: 2024/03/01

Less

4-Aminophenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

light yellow to beige powder. Soluble in alcohols and alkalis, slightly soluble in hot water.

Uses

4-Aminophenylacetic acid is used as a non-translocated competitive inhibitor of the epithelial peptide transporter PepT1. It can be detected using HPLC, NMR techniques.

Preparation

p-aminophenylacetic acid is obtained by the reduction of 4-nitrophenylacetic acid. In a reactor, water, 4-nitrophenylacetic acid, and acetic acid are added. The mixture is stirred and heated to 90-95℃. Iron powder is added in portions and refluxed for 2 hours. The mixture is cooled to 40-50℃ and neutralized with sodium carbonate to pH=9, then filtered. The filtrate is further neutralized with acetic acid until pH=4, resulting in the precipitation of 4-aminophenylacetic acid. The yield is 95%.

Purification Methods

Crystallise the acid from hot water (60-70mL/g). [Beilstein 14 III 1182.]

References

[1] BEDAIRAHMED H. Preparation of 4-aminophenylacetic acid derivatives with promising antimicrobial activity.[J]. Acta Pharmaceutica, 2006, 56 3: 273-284.
[2] MENGYIFAN ZareRichard N GnanamaniElumalai. One-Step Formation of Pharmaceuticals Having a Phenylacetic Acid Core Using Water Microdroplets.[J]. Journal of the American Chemical Society, 2023, 145 14: 7724-7728. DOI:10.1021/jacs.3c00773.

4-Aminophenylacetic acid Preparation Products And Raw materials

Raw materials

4-Nitrophenylacetic acid Iron

Preparation Products

METHYL 2-AMINO-2-(4-HYDROXYPHENYL)ACETATE METHYL 6-QUINOLINEACETATE 4-(DIMETHYLAMINO)PHENYLACETIC ACID DL-4-HYDROXYPHENYLGLYCINE (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-phenylacetic acid 4-Hydroxyphenylacetic acid ALPHA-AMINOBENZENEACETYL CHLORIDE

Less

4-Aminophenylacetic acid Suppliers

Americas 1 Belgium 3 Canada 4 China 349 Europe 3 France 1 Germany 8 India 36 Japan 3 Slovakia 1 South Korea 2 Switzerland 3 Ukraine 1 United Kingdom 18 United States 44 USA 1 Global 478

Mashilabs (Shanghai) Co.,Ltd.

Tel: 021-00000000 19916721580
Fax: QQ：3154870176
Email: info@mashilabs.com
Country: China
ProdList: 4115
Advantage: 58

Lianyungang Xuanyuan Chemical Co., Ltd

Tel: 0518-85415818; 18000194506
Email: 2818153737@qq.com
Country: China
ProdList: 48
Advantage: 58

Henan Guangwo New Materials Co., Ltd

Tel: 15225201380 18336995067
Email: 3656693041@qq.com
Country: China
ProdList: 1552
Advantage: 58

Shanghai Runna Chemical Technology Co., Ltd

Tel: 13041691910 13817852019
Email: runnahuagong@126.com
Country: China
ProdList: 33
Advantage: 58

HANGZHOU LOOP BIOTECH CO., LTD.

Tel: 0571-85810519 13396556070
Email: sales01@looppharm.com
Country: China
ProdList: 42
Advantage: 58

Cangzhou Kangrui Medical Technology Co., LTD

Tel: 18632776803
Email: 355803330@qq.com
Country: China
ProdList: 525
Advantage: 58

Jiaxing Jilat Chemical Co. LTD

Tel: 0573-82813639 15157377625
Fax: 0573-82813637
Email: sales@jlightchem.com
Country: China
ProdList: 141
Advantage: 58

Tai 'an Huanyu Chemical Co., LTD

Tel: 13176825516
Email: 78995114@qq.com
Country: China
ProdList: 32
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 668
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12426
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9552
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17940
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

SpringPharma Tech Co.,Ltd

Tel: +86-25-68710855, +86-25-68710897
Fax: 025-68710856
Email: sales@springpharma.net
Country: China
ProdList: 1261
Advantage: 62

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11714
Advantage: 57

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 15343847665
Fax: QQ：3470079902
Email: huawenchem@163.com
Country: China
ProdList: 3206
Advantage: 55

Shanghai Sphchem Co., Ltd.

Tel: 21-21-56491756 13512199871
Fax: 021-5649-1756
Email: sales@panhongchem.com
Country: China
ProdList: 3989
Advantage: 55

Shanghai Nuohey Chemical Co., Ltd.

Tel: 021-52212593 13761626812
Fax: +86 (21) 51062076
Email: sales@nuohey.com
Country: China
ProdList: 10692
Advantage: 60

NingBo Sialon Chem Co., Ltd.

Tel: 0574-28809768 18658497215
Fax: +86-574-56708448 / 28809708
Email: sales@newsialon.com
Country: China
ProdList: 40
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5654
Advantage: 65

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Beijing Century Richap Chemistry Co., Ltd.

Tel: 10-10-64446226
Fax: +86 10 64455595
Email: info@bj-newcenturychem.com
Country: China
ProdList: 110
Advantage: 55

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17779
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6181
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18216
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25004
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9552
Advantage: 55

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4576
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9906
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7876
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8033
Advantage: 55

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3933
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9908
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41132
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2931
Advantage: 58

Shanghai DiBai Chemicals Co., Ltd.

Tel: 021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3993
Advantage: 60

Less

View Lastest Price from 4-Aminophenylacetic acid manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: 4-Aminophenylacetic acid 1197-55-3
Price: US $2.00-1.50/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 10000ton
Release date: 2024-04-10

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: (4-Aminophenyl)acetic acid 1197-55-3
Price: US $100.00-30.00/kg
Min. Order: 1kg
Purity: 99.3%
Supply Ability: 1 ton per week
Release date: 2024-04-10

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: 4-Aminophenylacetic acid 1197-55-3
Price: US $50.00-35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000000kg
Release date: 2024-04-10

1197-55-3, 4-Aminophenylacetic acidRelated Search:

Folic acid Citric acid 4-Amino-benzenesulfonic acid monosodium salt 4-Aminophenylboronic acid p-Anisidine Sulfanilic acid 4-Aminophenylacetic acid nitrile Hyaluronic acid 4-Aminobenzoic acid 4-Aminobenzaldehyde Stearic acid 4-Aminoacetophenone METHYL 4-(4-AMINOPHENYL)BUTANOATE Ethyl 2-(Chlorosulfonyl)acetate 4-Aminobenzonitrile Phenetidine Sulfanilamide 4-Aminothiophenol

2-(4-aminophenyl)acetate

H-4-APH-OH

H-APH(4)-OH

2-(4-AMINOPHENYL)ACETIC ACID

4-AMINOPHENYLACETIC ACID

ACETIC ACID 4-AMINOPHENYL ESTER

AKOS BBS-00006880

RARECHEM AL BO 0220

P-AMINOPHENYLACETIC ACID

Phenylglycine base

4-Aminophenylacetic

Benzeneacetic acid, 4-amino-

4-AMINOPHENYLACETIC ACID 98+%

Desacetyl Actarit

NSC 7929

4-AMino acid

4-Aminophenylacetic acid Vetec(TM) reagent grade, 98%

4-AMINOPHENYLACETIC ACID, VETEC

(p-aminophenyl)-aceticaci

(para-Aminophenyl)acetic acid

4-Aminobenzeneacetic acid

4-amino-benzeneaceticaci

4-aminobenzeneaceticacid

4-Carboxymethylaniline

Acetic acid, (p-aminophenyl)-

p-Amino-alpha-toluic acid

p-amino-alpha-toluicacid

4-AMINOPHENYLACETIC ACID FOR SYNTHESIS

p-Amino-alph

4-Aminophenylessigsure

4-Aminophenylacetic Acid &gt

4-Aminophenylaceticaci

4-Aminophenylacetic acid USP/EP/BP

1197-55-3

2003-01-5

C8H8NO2

Carboxylic acid

Others

Peptide Synthesis

Specialty Synthesis

Unnatural Amino Acid Derivatives

Naphthyridine,Quinoline

Others

Peptide Synthesis

Unnatural Amino Acid Derivatives

FINE Chemical & INTERMEDIATES

Aromatic Phenylacetic Acids and Derivatives

Carboxylic Acids

Phenyls & Phenyl-Het

Organic acids

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals

Carboxylic Acids

Phenyls & Phenyl-Het