D-Aspartic acid
- Product Name
- D-Aspartic acid
- CAS No.
- 1783-96-6
- Chemical Name
- D-Aspartic acid
- Synonyms
- D-ASP;D-(-)-ASPARTIC ACID;H-D-ASP-OH;(R)-2-AMINOSUCCINIC ACID;Aspartic acid D-form;H-D-Asp;D-Asp-OH;NSC 97922;d-aspartic;xuyicaoyou
- CBNumber
- CB6373566
- Molecular Formula
- C4H7NO4
- Formula Weight
- 133.1
- MOL File
- 1783-96-6.mol
D-Aspartic acid Property
- Melting point:
- >300 °C(lit.)
- alpha
- -25.8 º (c=5, 5N HCl)
- Boiling point:
- 245.59°C (rough estimate)
- Density
- 1.66
- refractive index
- -25 ° (C=8, 50% HCl)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Aqueous Acid (Sparingly)
- pka
- pK1: 1.89(0);pK2: 3.65;pK3: 9.60 (25°C)
- form
- Crystalline Powder
- color
- White to off-white
- optical activity
- [α]20/D 24°, c = 2.3 in 6 M HCl
- Water Solubility
- SOLUBLE
- Merck
- 14,840
- BRN
- 1723529
- InChIKey
- CKLJMWTZIZZHCS-UWTATZPHSA-N
- LogP
- -1.075 (est)
- CAS DataBase Reference
- 1783-96-6(CAS DataBase Reference)
- NIST Chemistry Reference
- D-aspartic acid(1783-96-6)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- RTECS
- CI9097500
- HS Code
- 29224995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 219096
- Product name
- D-Aspartic acid
- Purity
- ReagentPlus , 99%
- Packaging
- 25g
- Price
- $174
- Updated
- 2025/07/31
- Product number
- 219096
- Product name
- D-Aspartic acid
- Purity
- ReagentPlus , 99%
- Packaging
- 100g
- Price
- $303.1
- Updated
- 2025/07/31
- Product number
- A0545
- Product name
- D-Aspartic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $70
- Updated
- 2025/07/31
- Product number
- 0213
- Product name
- D-Aspartic acid
- Packaging
- 1G
- Price
- $99
- Updated
- 2021/12/16
- Product number
- A790020
- Product name
- D-Aspartic acid
- Packaging
- 25g
- Price
- $70
- Updated
- 2021/12/16
D-Aspartic acid Chemical Properties,Usage,Production
Chemical Properties
White or almost white crystalline powder
Uses
D-Aspartic acid modulates melatonin synthesis in the pineal gland.
Uses
A non-essential amino acid found in food sources and dietary supplements. D-Aspartic acid's conjugate base D-aspartate has potential use as a a therapeutic agent in the treatment of schizophrenia-related symptoms.
Definition
ChEBI: The D-enantiomer of aspartic acid.
reaction suitability
reaction type: solution phase peptide synthesis
Biological Activity
Endogenous NMDA receptor agonist with similar activity to the L-isomer (L-Aminosuccinic acid ). Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.
Synthesis
6384-18-5
1783-96-6
In a reaction vessel, 4.85 g (0.03 mol) of dimethyl (S)-2-aminosuccinate was added to 50 mL of 6 M potassium hydroxide solution and the hydrolysis reaction was carried out by heating and refluxing for 3 hrs. Upon completion of the reaction, the pH of the reaction solution was adjusted to 6.5 with 6 N hydrochloric acid.The reaction solution was purified by passing it through a regenerated cation exchange resin column and the effluent with pH=4 was collected. The collected effluent was concentrated under reduced pressure to one-fifth of the original volume and then precipitated by adding 95% methanol. The precipitate was collected by filtration and dried to give 3.3 g of D-aspartic acid in 82.5% yield.
storage
Room temperature
References
[1] Patent: CN105503628, 2016, A. Location in patent: Paragraph 0026
D-Aspartic acid Preparation Products And Raw materials
Raw materials
Preparation Products
D-Aspartic acid Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from D-Aspartic acid manufacturers
- Product
- D-Aspartic acid 1783-96-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min AJI
- Supply Ability
- 1000kg
- Release date
- 2025-10-21
- Product
- D-Aspartic acid 1783-96-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-09-29
- Product
- D-Aspartic acid 1783-96-6
- Price
- US $16.00/KG
- Min. Order
- 50Kg/Drum
- Purity
- 98%
- Supply Ability
- 1000T
- Release date
- 2021-06-04