1-Chloroethyl isopropyl carbonate
- Product Name
- 1-Chloroethyl isopropyl carbonate
- CAS No.
- 98298-66-9
- Chemical Name
- 1-Chloroethyl isopropyl carbonate
- Synonyms
- JCC-1;1-CHLOROETHYL ISOPROPYL CARBONATE;1-Chloroethyl lsopropyl Carbonate;1-Chloroethyl Isopropyl Carbonate >1-(isopropoxycarbonyloxy)ethyl chloride;1-Chloroethyl Isopropyl Carbonate (JCC-1);1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC);1-Chloroethyl isopropyl carbonate (1-CEIC);CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER;1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)
- CBNumber
- CB6379609
- Molecular Formula
- C6H11ClO3
- Formula Weight
- 166.6
- MOL File
- 98298-66-9.mol
1-Chloroethyl isopropyl carbonate Property
- Boiling point:
- 70 °C / 15mmHg
- Density
- 1.113±0.06 g/cm3(Predicted)
- refractive index
- 1.4110-1.4150
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- clear liquid
- color
- Colorless to Almost colorless
- InChI
- InChI=1S/C6H11ClO3/c1-4(2)9-6(8)10-5(3)7/h4-5H,1-3H3
- InChIKey
- XPTPAIJDVFQPJT-UHFFFAOYSA-N
- SMILES
- C(OC(C)C)(=O)OC(Cl)C
- LogP
- 1.37 at 20℃
- CAS DataBase Reference
- 98298-66-9(CAS DataBase Reference)
Safety
- Risk Statements
- 10-34
- Safety Statements
- 16-36/37/39
- RIDADR
- 2920
- HS Code
- 2915.90.5010
- HazardClass
- 8/3
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1787
- Product name
- 1-Chloroethyl Isopropyl Carbonate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $44
- Updated
- 2024/03/01
- Product number
- C1787
- Product name
- 1-Chloroethyl Isopropyl Carbonate
- Purity
- >98.0%(GC)
- Packaging
- 250g
- Price
- $200
- Updated
- 2024/03/01
- Product number
- C984675
- Product name
- 1-Chloroethyl Isopropyl Carbonate
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 241282
- Product name
- 1-Chloroethyl Isopropyl Carbonate
- Purity
- 98%
- Packaging
- 1g
- Price
- $12
- Updated
- 2021/12/16
- Product number
- FC139704
- Product name
- 1-Chloroethyl isopropyl carbonate
- Packaging
- 10g
- Price
- $50
- Updated
- 2021/12/16
1-Chloroethyl isopropyl carbonate Chemical Properties,Usage,Production
Uses
1-Chloroethyl Isopropyl-d7 Carbonate is an intermediate in the synthesis of Cefpodoxime Proxetil-d7 (C243862). Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850).
1-Chloroethyl isopropyl carbonate is an efficient and mild reagent for removing benzyl protecting groups, especially for compounds containing functional groups that are easily reduced.
Synthesis
To a solution of 2-propanol (2.66 mL, 34.97 mmol) and pyridine (3.39 mL, 41.96 mmol), pre-cooled in a dry-ice/acetone bath was slowly added 1-chloroethyl chloroformate. The resulting mixture was allowed to slowly warm to 25° C. overnight, with stirring. After concentration under reduced pressure, the mixture was dissolved in ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated under reduced pressure to give 1-chloroethyl isopropyl carbonate as a pink/orange oil (5.11 g, 88% yield).
1-Chloroethyl isopropyl carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Chloroethyl isopropyl carbonate manufacturers
- Product
- 1-Chloroethyl isopropyl carbonate 98298-66-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-29
- Product
- 1-Chloroethyl isopropyl carbonate 98298-66-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 1-Chloroethyl isopropyl carbonate 98298-66-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08