ChemicalBook > CAS DataBase List > 1-Chloroethyl isopropyl carbonate

1-Chloroethyl isopropyl carbonate

Product Name
1-Chloroethyl isopropyl carbonate
CAS No.
98298-66-9
Chemical Name
1-Chloroethyl isopropyl carbonate
Synonyms
JCC-1;1-CHLOROETHYL ISOPROPYL CARBONATE;1-Chloroethyl lsopropyl Carbonate;1-Chloroethyl Isopropyl Carbonate >1-(isopropoxycarbonyloxy)ethyl chloride;1-Chloroethyl Isopropyl Carbonate (JCC-1);1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC);1-Chloroethyl isopropyl carbonate (1-CEIC);CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER;1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)
CBNumber
CB6379609
Molecular Formula
C6H11ClO3
Formula Weight
166.6
MOL File
98298-66-9.mol
More
Less

1-Chloroethyl isopropyl carbonate Property

Boiling point:
70 °C / 15mmHg
Density 
1.113±0.06 g/cm3(Predicted)
refractive index 
1.4110-1.4150
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Almost colorless
InChI
InChI=1S/C6H11ClO3/c1-4(2)9-6(8)10-5(3)7/h4-5H,1-3H3
InChIKey
XPTPAIJDVFQPJT-UHFFFAOYSA-N
SMILES
C(OC(C)C)(=O)OC(Cl)C
LogP
1.37 at 20℃
CAS DataBase Reference
98298-66-9(CAS DataBase Reference)
More
Less

Safety

Risk Statements 
10-34
Safety Statements 
16-36/37/39
RIDADR 
2920
HS Code 
2915.90.5010
HazardClass 
8/3
PackingGroup 
II
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C1787
Product name
1-Chloroethyl Isopropyl Carbonate
Purity
>98.0%(GC)
Packaging
25g
Price
$44
Updated
2024/03/01
TCI Chemical
Product number
C1787
Product name
1-Chloroethyl Isopropyl Carbonate
Purity
>98.0%(GC)
Packaging
250g
Price
$200
Updated
2024/03/01
TRC
Product number
C984675
Product name
1-Chloroethyl Isopropyl Carbonate
Packaging
2.5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
Z5422
Product name
1-Chloroethyl Isopropyl Carbonate
Packaging
5g
Price
$77
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC139704
Product name
1-Chloroethyl isopropyl carbonate
Packaging
25g
Price
$100
Updated
2021/12/16
More
Less

1-Chloroethyl isopropyl carbonate Chemical Properties,Usage,Production

Uses

1-Chloroethyl Isopropyl-d7 Carbonate is an intermediate in the synthesis of Cefpodoxime Proxetil-d7 (C243862). Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850).
1-Chloroethyl isopropyl carbonate is an efficient and mild reagent for removing benzyl protecting groups, especially for compounds containing functional groups that are easily reduced.

Synthesis

To a solution of 2-propanol (2.66 mL, 34.97 mmol) and pyridine (3.39 mL, 41.96 mmol), pre-cooled in a dry-ice/acetone bath was slowly added 1-chloroethyl chloroformate. The resulting mixture was allowed to slowly warm to 25° C. overnight, with stirring. After concentration under reduced pressure, the mixture was dissolved in ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated under reduced pressure to give 1-chloroethyl isopropyl carbonate as a pink/orange oil (5.11 g, 88% yield).

1-Chloroethyl isopropyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-Chloroethyl isopropyl carbonate Suppliers

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4772
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Anqing PhiChem Corporation
Tel
0556-5209970
Fax
0556-5209971
Email
salesaq@phichem.com.cn
Country
China
ProdList
36
Advantage
65
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9513
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Yaqee Industrial Corporation Limited
Tel
+86-561-5269788, 5209788
Fax
+86-561-5209268
Country
China
ProdList
40
Advantage
66
More
Less

View Lastest Price from 1-Chloroethyl isopropyl carbonate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1-Chloroethyl isopropyl carbonate 98298-66-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-29
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Chloroethyl isopropyl carbonate 98298-66-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Chloroethyl isopropyl carbonate 98298-66-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

98298-66-9, 1-Chloroethyl isopropyl carbonateRelated Search:


  • 1-CHLOROETHYL ISOPROPYL CARBONATE
  • CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER
  • JCC-1
  • 1-Chloroethyl Isopropyl Carbonate (JCC-1)
  • 1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC)
  • Carbonic acid, 1-chloroethyl-, 1-methyl-, ethyl ester
  • 1-Chloroethyl lsopropyl Carbonate
  • 1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)
  • 1-(isopropoxycarbonyloxy)ethyl chloride
  • 1-CHLOROETHYL ISOPROPYL CARBONATE (JCC-1)(INTERMEDIATE OF CEFPODOXIME PROXETIL (BANAN))
  • 1-chloroethyl isopropyl carbonate (intermediate of cefpodoxime proxetil)
  • 1-Chloroethyl Isopropyl Carbonate &gt
  • 1-Chloroethyl isopropyl carbonate (1-CEIC)
  • Carbonic acid 1-chloro-ethyl ester isopropyl ester
  • 98298-66-9
  • C6H10ClO3
  • CARBONATES
  • (intermediate of cefpodoxime proxetil)
  • bc0001