1-Chloroethyl cyclohexyl carbonate
- Product Name
- 1-Chloroethyl cyclohexyl carbonate
- CAS No.
- 99464-83-2
- Chemical Name
- 1-Chloroethyl cyclohexyl carbonate
- Synonyms
- 1 - chloroethyl cyclohexyl;ChloroethylCyclohexylCarbonate;1-Chloroethyl cyclohexyl carbote;CYCLOHEXYL 1-CHLOROETHYLCARBONATE;Candesartan Cilexetil Impurity 25;1-CHLOROETHYL CYCLOHEXYL CARBONATE;1-Chloroethyl cycvohexyl carbonate;1-Chloroehtyl cyclohexyl carbonate;chloro-1-ethylcyclohexyl carbonate;1-Chloroethyl Cyclohexyl Carbonate >
- CBNumber
- CB9180662
- Molecular Formula
- C9H15ClO3
- Formula Weight
- 206.67
- MOL File
- 99464-83-2.mol
1-Chloroethyl cyclohexyl carbonate Property
- Boiling point:
- 283.9±19.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- refractive index
- 1.4540-1.4580
- Flash point:
- 84 °C
- storage temp.
- 2-8°C
- solubility
- Chloroform (Sparingly), Ethyl Acetate, Methanol (Slightly)
- form
- Oil
- color
- Colourless
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C9H15ClO3/c1-7(10)12-9(11)13-8-5-3-2-4-6-8/h7-8H,2-6H2,1H3
- InChIKey
- ONZWFHWHTYZZLM-UHFFFAOYSA-N
- SMILES
- C(OC1CCCCC1)(=O)OC(Cl)C
- CAS DataBase Reference
- 99464-83-2(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- RIDADR
- 1760
- HS Code
- 2915.90.5010
- HazardClass
- 8
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1786
- Product name
- 1-Chloroethyl Cyclohexyl Carbonate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- C1786
- Product name
- 1-Chloroethyl Cyclohexyl Carbonate
- Purity
- >98.0%(GC)
- Packaging
- 250g
- Price
- $117
- Updated
- 2025/07/31
- Product number
- C367640
- Product name
- 1-Chloroethyl Cyclohexyl Carbonate
- Packaging
- 1g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- G250
- Product name
- 1-Chloroethyl Cyclohexyl Carbonate
- Packaging
- 5g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- 090651
- Product name
- 1-Chloroethyl cyclohexyl carbonate
- Purity
- 95+%
- Packaging
- 25g
- Price
- $39
- Updated
- 2021/12/16
1-Chloroethyl cyclohexyl carbonate Chemical Properties,Usage,Production
Chemical Properties
Colorless or pale yellow liquid
Uses
1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist.
Synthesis
1-chloroethyl chloroformate (1.99 g, 1.5 mL, 13.9 mmol) was reacted with cyclohexanol (1.33 g, 1.4 mL, 13.3 mmol) and pyridine (1.27 g, 1.3 mL, 16.1 mmol) in methylene chloride (11 mL) at ?78° C. for 3 h to give 1-chloroethyl cyclohexyl carbonate.
References
[1] Patent: US2008/125483, 2008, A1. Location in patent: Page/Page column 6-7
[2] Patent: WO2009/118580, 2009, A2. Location in patent: Page/Page column 17-18
[3] Patent: EP2526945, 2012, A1. Location in patent: Page/Page column 66
[4] Patent: WO2009/66917, 2009, A2. Location in patent: Page/Page column 17-18
[5] Patent: EP1477482, 2004, A1. Location in patent: Page 30
1-Chloroethyl cyclohexyl carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
1-Chloroethyl cyclohexyl carbonate Suppliers
- Tel
- 13523980263; 13523980263
- 1838829861@qq.com
- Country
- China
- ProdList
- 39
- Advantage
- 58
- Tel
- 0556-5209970
- Fax
- 0556-5209971
- salesaq@phichem.com.cn
- Country
- China
- ProdList
- 36
- Advantage
- 65
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-60275820 13031183356
- Fax
- 010-60270825
- elainezt@sina.com
- Country
- China
- ProdList
- 1390
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
View Lastest Price from 1-Chloroethyl cyclohexyl carbonate manufacturers
- Product
- 1-Chloroethyl cyclohexyl carbonate 99464-83-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- 1-Chloroethyl cyclohexyl carbonate 99464-83-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-29
- Product
- 1-Chloroethyl cyclohexyl carbonate 99464-83-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99.%
- Supply Ability
- 10 ton
- Release date
- 2024-08-19