1-Chloroethyl isopropyl carbonate

Product Name: 1-Chloroethyl isopropyl carbonate
CAS No.: 98298-66-9
Chemical Name: 1-Chloroethyl isopropyl carbonate
Synonyms: JCC-1;1-CHLOROETHYL ISOPROPYL CARBONATE;1-Chloroethyl lsopropyl Carbonate;1-Chloroethyl Isopropyl Carbonate >1-(isopropoxycarbonyloxy)ethyl chloride;1-Chloroethyl Isopropyl Carbonate (JCC-1);1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC);1-Chloroethyl isopropyl carbonate (1-CEIC);CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER;1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)
CBNumber: CB6379609
Molecular Formula: C6H11ClO3
Formula Weight: 166.6
MOL File: 98298-66-9.mol

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1-Chloroethyl isopropyl carbonate Property

Boiling point:: 70 °C / 15mmHg
Density: 1.113±0.06 g/cm3(Predicted)
refractive index: 1.4110-1.4150
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: clear liquid
color: Colorless to Almost colorless
InChI: InChI=1S/C6H11ClO3/c1-4(2)9-6(8)10-5(3)7/h4-5H,1-3H3
InChIKey: XPTPAIJDVFQPJT-UHFFFAOYSA-N
SMILES: C(OC(C)C)(=O)OC(Cl)C
LogP: 1.37 at 20℃
CAS DataBase Reference: 98298-66-9(CAS DataBase Reference)

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Safety

Risk Statements: 10-34
Safety Statements: 16-36/37/39
RIDADR: 2920
HS Code: 2915.90.5010
HazardClass: 8/3
PackingGroup: II

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C1787
Product name: 1-Chloroethyl Isopropyl Carbonate
Purity: >98.0%(GC)
Packaging: 25g
Price: $44
Updated: 2024/03/01

TCI Chemical

Product number: C1787
Product name: 1-Chloroethyl Isopropyl Carbonate
Purity: >98.0%(GC)
Packaging: 250g
Price: $200
Updated: 2024/03/01

TRC

Product number: C984675
Product name: 1-Chloroethyl Isopropyl Carbonate
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

Oakwood

Product number: 241282
Product name: 1-Chloroethyl Isopropyl Carbonate
Purity: 98%
Packaging: 1g
Price: $12
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC139704
Product name: 1-Chloroethyl isopropyl carbonate
Packaging: 10g
Price: $50
Updated: 2021/12/16

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1-Chloroethyl isopropyl carbonate Chemical Properties,Usage,Production

Uses

1-Chloroethyl Isopropyl-d7 Carbonate is an intermediate in the synthesis of Cefpodoxime Proxetil-d7 (C243862). Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850).
1-Chloroethyl isopropyl carbonate is an efficient and mild reagent for removing benzyl protecting groups, especially for compounds containing functional groups that are easily reduced.

Synthesis

To a solution of 2-propanol (2.66 mL, 34.97 mmol) and pyridine (3.39 mL, 41.96 mmol), pre-cooled in a dry-ice/acetone bath was slowly added 1-chloroethyl chloroformate. The resulting mixture was allowed to slowly warm to 25° C. overnight, with stirring. After concentration under reduced pressure, the mixture was dissolved in ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated under reduced pressure to give 1-chloroethyl isopropyl carbonate as a pink/orange oil (5.11 g, 88% yield).

1-Chloroethyl isopropyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

Cefpodoxime proxetil

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1-Chloroethyl isopropyl carbonate Suppliers

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View Lastest Price from 1-Chloroethyl isopropyl carbonate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1-Chloroethyl isopropyl carbonate 98298-66-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Chloroethyl isopropyl carbonate 98298-66-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Chloroethyl isopropyl carbonate 98298-66-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

98298-66-9, 1-Chloroethyl isopropyl carbonateRelated Search:

Isopropyl alcohol Sodium carbonate N,N-Diisopropylethylamine ISOPROPYL LAURATE Chloromethyl isopropyl carbonate Polycarbonate Barium carbonate Zinc carbonate Isopropyl acetate Ethylene carbonate Vinylene carbonate Calcium carbonate Dimethyl carbonate Propylene carbonate Ammonium carbonate 1-Chloroethyl cyclohexyl carbonate Chloromethyl ethyl carbonate 1-Chloroethyl ethyl carbonate

1-CHLOROETHYL ISOPROPYL CARBONATE

CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER

JCC-1

1-Chloroethyl Isopropyl Carbonate (JCC-1)

1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC)

Carbonic acid, 1-chloroethyl-, 1-methyl-, ethyl ester

1-Chloroethyl lsopropyl Carbonate

1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)

1-(isopropoxycarbonyloxy)ethyl chloride

1-CHLOROETHYL ISOPROPYL CARBONATE (JCC-1)(INTERMEDIATE OF CEFPODOXIME PROXETIL (BANAN))

1-chloroethyl isopropyl carbonate (intermediate of cefpodoxime proxetil)

1-Chloroethyl Isopropyl Carbonate &gt

1-Chloroethyl isopropyl carbonate (1-CEIC)

Carbonic acid 1-chloro-ethyl ester isopropyl ester

98298-66-9

C6H10ClO3

CARBONATES

(intermediate of cefpodoxime proxetil)

bc0001