Methyl 5-bromonicotinate

Product Name: Methyl 5-bromonicotinate
CAS No.: 29681-44-5
Chemical Name: Methyl 5-bromonicotinate
Synonyms: BUTTPARK 37\04-20;METHYL 5-BROMONICOTINATE;Methyl5-Bromonicotinate>5-bromopyridine-3-carboxyL;Methyl 5-bromonicotinate,98%;Methyl 5-bromonicotinate, 97%,;5-Bromonictinic acid ethyl ester;5-BROMONICOTIC ACID METHYL ESTER;5-BROMO NICOTINIC ACID METHYL ESTER;3-(Methoxycarbonyl)-5-bromopyridine
CBNumber: CB6384490
Molecular Formula: C7H6BrNO2
Formula Weight: 216.03
MOL File: 29681-44-5.mol

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Methyl 5-bromonicotinate Property

Melting point:: 96-100 °C
Boiling point:: 241.7±20.0 °C(Predicted)
Density: 1.579±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: solid
pka: 0.84±0.20(Predicted)
color: White
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C7H6BrNO2/c1-11-7(10)5-2-6(8)4-9-3-5/h2-4H,1H3
InChIKey: AAJZXPWBILCHAW-UHFFFAOYSA-N
SMILES: C1=NC=C(Br)C=C1C(OC)=O
CAS DataBase Reference: 29681-44-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-39-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 657425
Product name: Methyl 5-bromopyridine-3-carboxylate
Purity: 97%
Packaging: 5g
Price: $99.1
Updated: 2024/03/01

TCI Chemical

Product number: M2008
Product name: Methyl 5-Bromonicotinate
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $32
Updated: 2024/03/01

TCI Chemical

Product number: M2008
Product name: Methyl 5-Bromonicotinate
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $90
Updated: 2024/03/01

Alfa Aesar

Product number: B20908
Product name: Methyl 5-bromonicotinate, 97%
Packaging: 5g
Price: $98.65
Updated: 2024/03/01

Alfa Aesar

Product number: B20908
Product name: Methyl 5-bromonicotinate, 97%
Packaging: 1g
Price: $24.2
Updated: 2021/12/16

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Methyl 5-bromonicotinate Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

A substrate used in a microwave-assisted, palladium-catalyzed arylation of acetone as its TMS enol ether.

Application

Methyl 5-bromonicotinate could be used to synthesize Pyridine alkaloids from Rubiaceae with various organometallic reagents by palladium-catalyzed cross-coupling reactions. This compound is a derivative of 5-bromonicotinic acid (BrnicH) which has been widely used in the last decade to obtain MOF materials with unique luminescence, magnetism, catalysis, and adsorption through assembling with lanthanide ions and transition metal ions, such as Cu(II), Co(II), Cd(II), Zn(II), and Pb(II)[1-2].

Synthesis

To an ice-cooled suspension of 5-bromo nicotinic acid (1.6g, 7.9 mmol) in diethyl ether (20ml), a solution of diazomethane in diethyl ether was added dropwise with stirring until the mixture remained yellow. The mixture was stirred for additional 15min (hood!), and the volatile compounds were removed by distillation in vaeuo. Finally, Methyl 5-bromonicotinate was obtained after purification[2].

References

[1] WENJIE LI . Syntheses, crystal structures, and properties of new metal–5-bromonicotinate coordination polymers[J]. Journal of Solid State Chemistry, 2015. DOI:10.1016/j.jssc.2015.01.002.
[2] Bracher, F., Papke, T. Total syntheses and antimicrobial activities of pyridine alkaloids from Rubiaceae. Monatsh Chem 126, 805–809 (1995). https://doi.org/10.1007/BF00807174

Methyl 5-bromonicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 5-bromonicotinate Suppliers

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View Lastest Price from Methyl 5-bromonicotinate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Methyl 5-bromonicotinate 29681-44-5
Price: US $10.00-8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-05

Career Henan Chemical Co

Product: Methyl 5-bromonicotinate 29681-44-5
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-17

29681-44-5, Methyl 5-bromonicotinateRelated Search:

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5-BROMOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER

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METHYL 3-BROMO-5-PYRIDINECARBOXYLATE

BUTTPARK 37\04-20

5-Bromonictinic acid ethyl ester

5-Bromonicotinic acid methyl ester, 5-Bromopyridine-3-carboxylic acid methyl ester, Methyl 5-bromonicotinate

3-(Methoxycarbonyl)-5-bromopyridine

Methyl 5-bromonicotinate,98%

5-BROMONICOTIC ACID METHYL ESTER

Methyl 5-bromopyridine-3-carboxylate,5-Bromonicotinic acid methyl ester, 5-Bromopyridine-3-carboxylic acid methyl ester, Methyl 5-bromonicotinate

Methyl 5-bromopyridine-3-carboxylate, 3-Bromo-5-(methoxycarbonyl)pyridine

5-Bromo-3-pyridinecarboxylic Acid Methyl Ester Methyl 5-Bromo-3-pyridinecarboxylate 5-Bromonicotinic Acid Methyl Ester

Methyl 5-bromopyridine-3-carboxylate 97%

Methyl5-Bromonicotinate&gt

5-bromopyridine-3-carboxyL

3-Pyridinecarboxylic acid, 5-bromo-, methyl ester

Methyl 5-Bromo-3-pyridinecarboxylate

Methyl 5-bromonicotinate ISO 9001：2015 REACH

Methyl 5-bromonicotinate, 97%,

3-Pyridinecarboxylic acid, 5-bromo-, methyl ester (9CI, ACI)

5-bromo-3-Pyridinecarboxylic acid methyl ester (9CI ACI)

29681-44-5

29681-44-15

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