3-Iodo-7-azaindole
- Product Name
- 3-Iodo-7-azaindole
- CAS No.
- 23616-57-1
- Chemical Name
- 3-Iodo-7-azaindole
- Synonyms
- 3-IODO-1H-PYRROLO[2,3-B]PYRIDINE;3-IODO-7-AZAINDOLE;7-AZA-3-IODOINDOLE;3-Iodo-7-azaindole 95%;3-Iodo-1,7-diaza-1H-indene;3-Iod-1H-pyrrolo[2,3-b]pyridin;1H-Pyrrolo[2,3-b]pyridine, 3-iodo-;3-Iodo-7-azaindole (3-Iodo-1H-pyrrolo[2,3-b]pyridine）
- CBNumber
- CB6388645
- Molecular Formula
- C7H5IN2
- Formula Weight
- 244.03
- MOL File
- 23616-57-1.mol
3-Iodo-7-azaindole Property
- Melting point:
- 190-194 °C
- Boiling point:
- 360.3±35.0 °C(Predicted)
- Density
- 2.12±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- form
- solid
- pka
- 6.07±0.20(Predicted)
- color
- Light yellow
- Sensitive
- Light Sensitive
- CAS DataBase Reference
- 23616-57-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-41-37/38-22
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 692298
- Product name
- 3-Iodo-7-azaindole
- Purity
- 95%
- Packaging
- 1g
- Price
- $42.6
- Updated
- 2023/06/20
- Product number
- I1198
- Product name
- 3-Iodo-1H-pyrrolo[2,3-b]pyridine
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $66
- Updated
- 2025/07/31
- Product number
- I1198
- Product name
- 3-Iodo-1H-pyrrolo[2,3-b]pyridine
- Purity
- min. 95.0 %
- Packaging
- 10G
- Price
- $270
- Updated
- 2025/07/31
- Product number
- I706380
- Product name
- 3-Iodo-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 020021
- Product name
- 3-Iodo-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
3-Iodo-7-azaindole Chemical Properties,Usage,Production
Chemical Properties
Solid
Synthesis
271-63-6
23616-57-1
4.2.1 Synthesis of 3-iodo-1H-pyrrolo[2,3-b]pyridine (2) 1H-pyrrolo[2,3-b]pyridine (1.00 g, 8.47 mmol) was dissolved in ethanol (40 mL), followed by the sequential addition of iodine (3.23 g, 12.71 mmol), potassium iodide (2.11 g, 12.71 mmol) and 1M sodium hydroxide solution (12.71 mL, 12.71 mmol). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the reaction solution was diluted with water and extracted with ethyl acetate (3 times). The organic phases were combined, washed sequentially with 5% sodium thiosulfate solution (twice) and saturated sodium chloride solution, dried over anhydrous magnesium sulfate, filtered and concentrated to give an orange solid crude product. The crude product was recrystallized from a solvent mixture of methanol and water to give the pure product 3-iodo-1H-pyrrolo[2,3-b]pyridine (2.00 g, 97% yield) as an orange solid. 1H NMR (300 MHz, DMSO-d6) δ (ppm): 12.11 (br, 1H), 8.26 (dd, J = 1.5, 4.8 Hz, 1H), 7.72 (d, J = 2.7 Hz, 1H), 7.69 (dd, J = 1.5, 7.8 Hz, 1H), 7.16 (dd, J = 4.8, 7.8 Hz, 1H ). 13C NMR (75 MHz, DMSO-d6) δ (ppm): 148.5, 144.2, 130.9, 128.5, 122.4, 116.9, 54.8.
References
[1] Angewandte Chemie - International Edition, 2012, vol. 51, # 11, p. 2722 - 2726
[2] Organic and Biomolecular Chemistry, 2011, vol. 9, # 9, p. 3139 - 3141
[3] Organic and Biomolecular Chemistry, 2011, vol. 9, # 14, p. 5129 - 5136
[4] European Journal of Medicinal Chemistry, 2016, vol. 108, p. 701 - 719
[5] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 14, p. 5153 - 5163
3-Iodo-7-azaindole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Iodo-7-azaindole manufacturers
- Product
- 3-Iodo-7-azaindole 23616-57-1
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2019-12-25