7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE

Product Name: 7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE
CAS No.: 227940-70-7
Chemical Name: 7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE
Synonyms: 7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE;3-Boc-7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane;7-Benzyl-3-Boc-3,7-dizalbicylclo[3.3.1]nonan-9-one;tert-butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate;7-Benzyl-9-oxo-3,7-diaza-bicyclo3.3.1none-3-carboxylic acid tert-butyl ester;tert-butyl (1r,5s)-7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate;7-Benzyl-9-oxo-3,7-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid tert-butyl ester;3,7-Diazabicyclo[3.3.1]nonane-3-carboxylic acid, 9-oxo-7-(phenylmethyl)-, 1,1-dimethylethyl ester
CBNumber: CB6407830
Molecular Formula: C19H26N2O3
Formula Weight: 330.42
MOL File: 227940-70-7.mol

More

Less

7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE Property

storage temp.: 2-8°C
Appearance: Off-white to light yellow Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Matrix Scientific

Product number: 069015
Product name: tert-Butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate
Purity: >95%
Packaging: 1g
Price: $365
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0379311
Product name: 7-BENZYL-3-BOC-3,7-DIAZABICYCLO-[3.3.1]-NONAN-9-ONE
Purity: 95.00%
Packaging: 5MG
Price: $504.06
Updated: 2021/12/16

Matrix Scientific

Product number: 069015
Product name: tert-Butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate
Purity: >95%
Packaging: 5g
Price: $645
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 35151
Product name: tert-Butyl7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate
Purity: 95+%
Packaging: 1g
Price: $650
Updated: 2021/12/16

Matrix Scientific

Product number: 069015
Product name: tert-Butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate
Purity: >95%
Packaging: 250mg
Price: $983
Updated: 2021/12/16

More

Less

7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE Chemical Properties,Usage,Production

Synthesis

50-00-0

79099-07-3

100-46-9

227940-70-7

To a solution of methanol (20 mL) containing N-tert-butoxycarbonyl-4-piperidone (3 g, 15.06 mmol), benzylamine (1.73 mL, 15.81 mmol), and acetic acid (0.86 mL, 15.06 mmol) was added a suspension of paraformaldehyde (1 g, in 30 mL of methanol) under stirring. The reaction mixture was heated to reflux and stirred for 1 hour, followed by the addition of paraformaldehyde (1 g) and continued stirring for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated. The concentrated residue was dissolved in ether (40 mL) and alkalized by adding 1M potassium hydroxide solution (20 mL). The organic layer was separated and the aqueous phase was extracted four times with ether. The organic phases were combined, dried with anhydrous sodium sulfate for 20 min, filtered and concentrated. The resulting yellow residue was purified by fast chromatography (silica gel 80 g, elution gradient: 0 to 50% ethyl acetate/hexane, 20 min) to afford tert-butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate (5 g, 100% yield). lRMS (ESI): m/z Calculated value [M+H]+ 330.19, measured value 362.9 ([M+MeOH]+).

References

[1] Patent: WO2008/55068, 2008, A2. Location in patent: Page/Page column 176-177
[2] Patent: WO2009/137503, 2009, A1. Location in patent: Page/Page column 57-58
[3] Patent: US2017/749, 2017, A1. Location in patent: Paragraph 0558
[4] Tetrahedron, 2015, vol. 71, # 15, p. 2241 - 2245
[5] Chemical communications (Cambridge, England), 2002, # 7, p. 673 - 675

7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE Suppliers

China 39 India 1 United Kingdom 1 United States 4 Global 45

Chengdu NoVi Biotechnology Co., Ltd.

Tel: 028-81458053
Fax: 028-81458053
Email: novibiotech@163.com sales@novi-biotech.com
Country: China
ProdList: 226
Advantage: 55

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1876
Advantage: 55

Nantong MYBio-pharm. Co., Ltd.

Tel: 0513-85921823 18662920231
Fax: 86-513-85012876
Email: sales@ntminyanmedical.com
Country: China
ProdList: 4108
Advantage: 58

Shanghai AQBioPharma Co., Ltd.

Tel: 13661411401
Fax: 51370935-8011
Email: yinglv.que@aqbiopharma.com.cn
Country: China
ProdList: 2930
Advantage: 58

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

BioPharmaMatrix,Inc.

Tel: 0510-86010668
Fax: 0510-86010668
Email: sales@biopharmamatrix.com
Country: China
ProdList: 4739
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

227940-70-7, 7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONERelated Search:

N-BENZYL-BISPIDINE R-3-(Dimethylaminomethyl)-N-Boc-piperidine N-[(3R)-3-PIPERIDINYLMETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER (R)-N-Boc-3-aminomethylpiperidine 3-N-Boc-Aminomethylpiperidine 3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE 3-Methyl-4-oxo-1-piperidinecarboxylic acid ethyl ester (S)-N-Boc-3-aminomethylpiperidine 1-BOC-3-METHYL-PIPERIDIN-4-ONE (S)-3-(Dimethylaminomethyl)-N-Boc-piperidine 7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONANE 7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE

7-BENZYL-3-BOC-3,7-DIAZABICYCLO[3.3.1]NONAN-9-ONE

7-Benzyl-9-oxo-3,7-diaza-bicyclo3.3.1none-3-carboxylic acid tert-butyl ester

7-Benzyl-3-Boc-3,7-dizalbicylclo[3.3.1]nonan-9-one

tert-butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate

7-Benzyl-9-oxo-3,7-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid tert-butyl ester

3-Boc-7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane

3,7-Diazabicyclo[3.3.1]nonane-3-carboxylic acid, 9-oxo-7-(phenylmethyl)-, 1,1-dimethylethyl ester

tert-butyl (1r,5s)-7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate

227940-70-7

pharmacetical