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Wogonin

Appearance
Product Name
Wogonin
CAS No.
632-85-9
Chemical Name
Wogonin
Synonyms
5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on;5,7-DIHYDROXY-8-METHOXYFLAVON;5,7-DIHYDROXY-8-METHOXYFLAVONE;5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-one;WOGONIN;vogonin;WOOGONIN;WILDYAMP.E;WOGONIN(RG);WOGONIN hplc
CBNumber
CB6408918
Molecular Formula
C16H12O5
Formula Weight
284.26
MOL File
632-85-9.mol
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Wogonin Property

Melting point:
203-206°C
Boiling point:
518.8±50.0 °C(Predicted)
Density 
1.420±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: ≥20mg/mL
pka
6.83±0.40(Predicted)
form 
Yellow solid
color 
Light Yellow to Yellow
λmax
319nm(EtOH)(lit.)
InChIKey
XLTFNNCXVBYBSX-UHFFFAOYSA-N
LogP
2.140 (est)
CAS DataBase Reference
632-85-9(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LK8331000
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W0769
Product name
Wogonin hydrate
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
681670
Product name
Wogonin hydrate
Packaging
10mg
Price
$273
Updated
2023/01/07
TCI Chemical
Product number
W0010
Product name
Wogonin
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$140
Updated
2024/03/01
TCI Chemical
Product number
W0010
Product name
Wogonin
Purity
>98.0%(HPLC)
Packaging
250mg
Price
$418
Updated
2024/03/01
Cayman Chemical
Product number
14248
Product name
Wogonin
Purity
≥98%
Packaging
5mg
Price
$64
Updated
2024/03/01
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Wogonin Chemical Properties,Usage,Production

Appearance

Yellow solid powder

Uses

Wogonin acts as an anti-inflammatory agent, attenuating ovalbumin antigen-influenced neutrophillic airway inflammation. In addition, it reverses multi-drug resistance of human myelogenous leukemia.

Definition

ChEBI: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.

General Description

Wogonin is a flavonoid component of Scutellaria baicalensis Georgi roots.

Biochem/physiol Actions

Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction.

storage

Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). 

Wogonin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Wogonin manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Elderberry 632-85-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95%,Elderberry proanthocyanidins 25%
Supply Ability
10000kg/Month
Release date
2023-09-11
Shaanxi Haibo Biotechnology Co., Ltd
Product
Scutellaria baicalensis extract 632-85-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%,90%,40%,10%
Supply Ability
10000kg/Month
Release date
2023-09-11
BINBO BIOLOGICAL CO.,LTD
Product
Wogonin 632-85-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
1000 kg
Release date
2024-04-07

632-85-9, WogoninRelated Search:


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  • Wogonin, S. baicalensis - CAS 632-85-9 - Calbiochem
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  • 5,7-DIHYDROXY-8-METHOXYFLAVON
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  • 2-Phenyl-5,7-dihydroxy-8-methoxy-4H-1-benzopyran-4-one
  • WOGONIN(RG)
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  • chemical reagent
  • pharmaceutical intermediate
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