ChemicalBook > CAS DataBase List > Diethyl methylmalonate

Diethyl methylmalonate

Product Name
Diethyl methylmalonate
CAS No.
609-08-5
Chemical Name
Diethyl methylmalonate
Synonyms
Diethyl 2-methylmalonate;METHYLMALONIC ACID DIETHYL ESTER;RARECHEM AL BI 0301;Diethylisosuccinate;Diethyl methylmalote;Diethyl methylmalona;Ethyl methylmalonate;Diethyl MethyMalonate;dlethylmethylmalonate;DIETHYL METHYLMALONATE
CBNumber
CB6410788
Molecular Formula
C8H14O4
Formula Weight
174.19
MOL File
609-08-5.mol
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Diethyl methylmalonate Property

Boiling point:
198-199 °C (lit.) 78-80 °C/10 mmHg
Density 
1.022 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.413(lit.)
Flash point:
170 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
1000mg/l
pka
13.13±0.46(Predicted)
form 
Liquid
Specific Gravity
1.013
color 
Clear colorless
PH
8 (1000mg/l, H2O, 20℃)
Water Solubility 
immiscible
BRN 
637028
InChIKey
UPQZOUHVTJNGFK-UHFFFAOYSA-N
LogP
1.256 (est)
CAS DataBase Reference
609-08-5(CAS DataBase Reference)
NIST Chemistry Reference
Propanedioic acid, methyl-, diethyl ester(609-08-5)
EPA Substance Registry System
Propanedioic acid, methyl-, diethyl ester (609-08-5)
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29171990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
126136
Product name
Diethyl methylmalonate
Purity
99%
Packaging
100g
Price
$72.8
Updated
2024/03/01
Sigma-Aldrich
Product number
126136
Product name
Diethyl methylmalonate
Purity
99%
Packaging
500g
Price
$262
Updated
2024/03/01
TCI Chemical
Product number
M0366
Product name
Diethyl Methylmalonate
Purity
>98.0%(GC)
Packaging
25mL
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
M0366
Product name
Diethyl Methylmalonate
Purity
>98.0%(GC)
Packaging
100mL
Price
$49
Updated
2024/03/01
Alfa Aesar
Product number
A12078
Product name
Diethyl methylmalonate, 99%
Packaging
50g
Price
$27.65
Updated
2024/03/01
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Diethyl methylmalonate Chemical Properties,Usage,Production

Chemical Properties

Colorless mobile liquid. Slightly soluble in water, soluble in alcohol and oils.

Physical properties

Colorless mobile liquid. Slightly soluble in water, soluble in alcohol and oils.

Uses

Diethyl methylmalonate is used as intermediate for the syntheses of pharmaceuticals, e.g. non-steroidal anti-inflammatory agents with 2-acrylpropionic acid structures acrylpropionic acid structure. It is also used in the flavour and fragrance industries. Product Data Sheet

Uses

Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.

General Description

Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.

Synthesis

Diethyl methylmalonate is produced by the following method:1) by condensing Ethylpropionate with Diethyloxalate, followed by heating of the reaction product. 2) from Diethylmalonate plus Sodium and Methyl iodide.

Diethyl methylmalonate Preparation Products And Raw materials

Raw materials

DIETHYL OXALPROPIONATE

Preparation Products

ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate 4,6-DIHYDROXY-5-METHYLPYRIMIDINE 2,5-Dimethylpyridine 7-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLIC ACID
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Diethyl methylmalonate Suppliers

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HBCChem, Inc.
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View Lastest Price from Diethyl methylmalonate manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Diethyl methylmalonate 609-08-5
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg/week
Release date
2021-06-09
Hebei Weibang Biotechnology Co., Ltd
Product
Diethyl methylmalonate 609-08-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-06
Hebei Kingfiner Technology Development Co.Ltd
Product
Diethyl methylmalonate 609-08-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2023-08-11

609-08-5, Diethyl methylmalonateRelated Search:

Methyl acrylate Dimethyl malonate 2-Hydroxyethyl methacrylate 2-Methylpropanedioic acid DIETHYL BROMOMALONATE Diethyl ethylmalonate Diethyl ketomalonate BUTYL OLEATE Diethyl dipropylmalonate Bensulfuron methyl Tris(trimethylsilyl)phosphate Methylparaben Diethyl isopropylmalonate Diethyl allylmalonate DIETHYL DIETHYLMALONATE Diethyl butylmalonate Diethyl 2-ethyl-2-phenylmalonate Diethyl phenylmalonate

  • RARECHEM AL BI 0301
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  • dlethylmethylmalonate
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  • Propanedioicacid, 2-Methyl-, 1,3-diethyl ester
  • DiethylMethylmalonate&gt
  • Diethyl Methylmalonate,>98%
  • Flurbiprofen Impurity 27
  • DEMM，Diethyl Methyl Malonate
  • 609-08-5
  • 608-08-5
  • C8H14O4
  • CH3CHCOOC2H52
  • COOC2H52CHCH3
  • Carbonyl Compounds
  • C8 to C9
  • Building Blocks
  • Esters
  • Organic Building Blocks
  • Building Blocks
  • C8 to C9
  • Carbonyl Compounds
  • Chemical Synthesis
  • Esters
  • Organic Building Blocks
  • Pharmaceutical Intermediates
  • Cyanoacetic acid esters
  • Hydrocyanic acid derivatives
  • bc0001