2-Aminoacetophenone hydrochloride

Product Name: 2-Aminoacetophenone hydrochloride
CAS No.: 5468-37-1
Chemical Name: 2-Aminoacetophenone hydrochloride
Synonyms: 2-aMino-1-phenylethan-1-one hydrochloride;PHENACYLAMINE HYDROCHLORIDE;α-Aminoacetophenone;Compound F0401-0089;2-amino-acetophenonhydrochlo;2-aminophenone hydrochloride;2-amino-acetophenonhydrochloride;O-AMINOACETOPHENONE HYDROCHLORIDE;2-AMINOACETOPHENONE HYDROCHLORIDE;ω-aminoacetophenone hydrochloride
CBNumber: CB6412186
Molecular Formula: C8H10ClNO
Formula Weight: 171.62
MOL File: 5468-37-1.mol

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2-Aminoacetophenone hydrochloride Property

Melting point:: 194 °C (dec.)(lit.)
storage temp.: Refrigerator (+4°C)
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Crystals
color: Slightly yellow to beige
BRN: 3563173
Stability:: Hygroscopic
InChI: InChI=1S/C8H9NO.ClH/c9-6-8(10)7-4-2-1-3-5-7;/h1-5H,6,9H2;1H
InChIKey: CVXGFPPAIUELDV-UHFFFAOYSA-N
SMILES: C(C1=CC=CC=C1)(=O)CN.[H]Cl
CAS DataBase Reference: 5468-37-1(CAS DataBase Reference)
EPA Substance Registry System: Ethanone, 2-amino-1-phenyl-, hydrochloride (5468-37-1)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26-24/25
WGK Germany: 3
RTECS: AM5940000
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29223990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A38207
Product name: 2-Aminoacetophenone hydrochloride
Purity: 99%
Packaging: 1g
Price: $27.72
Updated: 2024/03/01

Sigma-Aldrich

Product number: A38207
Product name: 2-Aminoacetophenone hydrochloride
Purity: 99%
Packaging: 5g
Price: $99.7
Updated: 2024/03/01

Alfa Aesar

Product number: H29117
Product name: 2-Aminoacetophenone hydrochloride, 97%
Packaging: 1g
Price: $44.65
Updated: 2024/03/01

Alfa Aesar

Product number: H29117
Product name: 2-Aminoacetophenone hydrochloride, 97%
Packaging: 10g
Price: $200.65
Updated: 2024/03/01

Alfa Aesar

Product number: H29117
Product name: 2-Aminoacetophenone hydrochloride, 97%
Packaging: 50g
Price: $569
Updated: 2021/12/16

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2-Aminoacetophenone hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-white crystalline

Uses

Mixed Salt of α-Aminoacetophenone, used in the preparation og pseudopeptidic inhibitors of human sirtuins1-3. This action effectually displays antiproliferative protperties in cancer cells. Also used in the preparation of dual δ/μopiod receptor agonists.

Synthesis

To a stirred solution of phenacyl bromide (1 mmol, 1 equiv) in diethyl ether (13 mL) was added hexamethylenetetramine (1 mmol, 1 equiv) all at once and the mixture was stirred for 12 h at room temperature. The resulting solid was filtered, washed with diethyl ether (15 mL), and dried under reduced pressure to afford the quaternary salt, which was next placed in a two-necked round-bottomed flask fitted with a reflux condenser, and EtOH (22 mL) was added to it. Concentrated HCl (0.6 mL) was added, and the mixture was refluxed for 3 h (solid formed). After cooling to room temperature, the solid was filtered, washed with EtOH (20 mL), and dried under vacuum to afford pure 2-Aminoacetophenone hydrochloride.

Purification Methods

Crystallise the salt from Me2CO /EtOH, EtOH/ Et2O, 2-propanol or 2-propanol and a little HCl (slowly after a fe

2-Aminoacetophenone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-PHENYLIMIDAZOLE

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2-Aminoacetophenone hydrochloride Suppliers

Belgium 1 China 221 Europe 2 Germany 5 Hungary 1 India 8 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 8 United States 25 Global 279

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Energy Chemical

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View Lastest Price from 2-Aminoacetophenone hydrochloride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Aminoacetophenone hydrochloride 5468-37-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Aminoacetophenone hydrochloride 5468-37-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Aminoacetophenone hydrochloride 5468-37-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

5468-37-1, 2-Aminoacetophenone hydrochlorideRelated Search:

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Ethanone,2-aMino-1-phenyl-, hydrochloride (1:1)

2-Aminoacetophenone*HCl (with ca. 4% NaCl)

2-amino-acetophenonhydrochloride

PHENACYLAMINE HYDROCHLORIDE

OMEGA-AMINOACETOPHENONE HYDROCHLORIDE

O-AMINOACETOPHENONE HYDROCHLORIDE

2-AMINOACETOPHENONE HYDROCHLORIDE

2-AMINO-1-PHENYL-ETHANONE HYDROCHLORIDE

ALPHA-AMINOACETOPHENONE HYDROCHLORIDE

2-OXO-2-PHENYL-ETHYL-AMMONIUM, CHLORIDE

ETHANONE, 2-AMINO-1-PHENYL-, HYDROCHLORIDE

2-Aminoacetophenone hydrochloride with 4% NaCl

w-Amino-acetophinone hydrochloride

ω-aminoacetophenone hydrochloride

w-Aminoacetophenone hydrochloride

aminomethylphenylketone hydrochloride

α-Aminoacetophenone (Mixed Salt, >85%)

α-Aminoacetophenone

α-Aminoacetophenone Hydrochloride

2-aminophenone hydrochloride

Compound F0401-0089

5468-37-1

15468-37-1

C6H5COCH2NH2HCl

C8H9NOClH

Organic Building Blocks

Ketones

Building Blocks

C7 to C8

Carbonyl Compounds

AMINE

Ketones

Organic Building Blocks

Building Blocks

C7 to C8

Carbonyl Compounds

Chemical Synthesis