ChemicalBook > CAS DataBase List > 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE

Product Name
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE
CAS No.
5617-70-9
Chemical Name
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE
Synonyms
Danishefsky's reagent;CYCLOPROPYL MELDRUM'S ACID;6,6-DiMethyl-5,7-dioxaspiro[2.5]octan-4,8-dione;6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE;3,3-Dimethyl-2,4-dioxaspiro[5.2]octane-1,5-dione;5,7-Dioxa-6,6-dimethylspiro[2.5]octane-4,8-dione;CYCL-ISOPROPYLIDENE CYCLOPROPANE-1,1-DICARBOXYLATE;6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-quinone;5,7-Dioxaspiro[2.5]octane-4,8-dione, 6,6-diMethyl-;6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione >
CBNumber
CB6433851
Molecular Formula
C8H10O4
Formula Weight
170.16
MOL File
5617-70-9.mol
More
Less

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE Property

Melting point:
63-65 °C(lit.)
Boiling point:
396.8±35.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMF: soluble(lit.)
form 
Solid
color 
White to Off-White
BRN 
1241835
InChIKey
AXJVPXNVESYGDT-UHFFFAOYSA-N
CAS DataBase Reference
5617-70-9(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2932209090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
341266
Product name
cyclic Isopropylidene 1,1-cyclopropanedicarboxylate
Purity
99%
Packaging
5g
Price
$67.8
Updated
2024/03/01
TCI Chemical
Product number
C1334
Product name
6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione
Purity
>98.0%(GC)
Packaging
1g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
C1334
Product name
6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione
Purity
>98.0%(GC)
Packaging
5g
Price
$82
Updated
2024/03/01
Alfa Aesar
Product number
L15571
Product name
6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione, 99%
Packaging
5g
Price
$87.65
Updated
2024/03/01
Alfa Aesar
Product number
L15571
Product name
6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione, 99%
Packaging
1g
Price
$26.1
Updated
2021/12/16
More
Less

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE Chemical Properties,Usage,Production

Uses

6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 7, p. 411, 1990
The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE Suppliers

Americas 1 China 69 Europe 1 France 1 Germany 4 India 20 Japan 1 Switzerland 1 United Kingdom 4 United States 14 Global 116
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
More
Less

View Lastest Price from 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE manufacturers

Career Henan Chemical Co
Product
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE 5617-70-9
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-09

5617-70-9, 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONERelated Search:

2,2,5-Trimethyl-1,3-dioxane-4,6-dione 1,1-Cyclopropanedicarboxylic acid monomethyl ester 2,2-Dimethyl-1,3-dioxane-4,6-dione 1,1-Cyclopropanedicarboxylic acid Cyclopropanecarboxylic acid 1,1-CYCLOPROPANEDICARBOXYLIC ACID MONOETHYL ESTER Ethyl cyclopropanecarboxylate ETHYL 1-METHYLCYCLOPROPANE-1-CARBOXYLATE Methyl cyclopropane carboxylate 1,1-Bis(hydroxymethyl)cyclopropane ISOBUTYRIC ACID ISOPROPYL ESTER 1-METHYLCYCLOPROPANE-1-CARBOXYLIC ACID METHYL ESTER 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE 3-Ethoxy-2,2-dimethyl-3-oxopropanoic acid FEMA 3699 Dimethylmalonic acid 1-Methylcyclopropanemethanol 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

  • 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE
  • CYCL-ISOPROPYLIDENE CYCLOPROPANE-1,1-DICARBOXYLATE
  • CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCL-ISOPROPYLIDENE ESTER
  • CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCLOISOPROPYLIDENE ESTER
  • 1,1-Cyclopropanedicarboxylic acid cycl-isopropylidene ester~cycl-Isopropylidene 1,1-cyclopropanedicarboxylate
  • CYCLOPROPYL MELDRUM'S ACID
  • Danishefsky's reagent
  • CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCL-ISOPRYLIDENE ESTER
  • Cyclopropane-1,1-dicarboxylic acid cyclic-isopropylidene ester
  • 1,1-Cyclopropanedicarboxylic acid cyclic isopropylidene ester, 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione
  • cyclic Isopropylidene 1,1-cyclopropanedicarboxylate
  • 2,2-Dimethylspiro[1,3-dioxane-5,1'-cyclopropane]-4,6-dione
  • 3,3-Dimethyl-2,4-dioxaspiro[5.2]octane-1,5-dione
  • 5,7-Dioxa-6,6-dimethylspiro[2.5]octane-4,8-dione
  • Cyclopropane-1,1-dicarboxylic acid isopropylidene ester
  • 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-quinone
  • 5,7-Dioxaspiro[2.5]octane-4,8-dione, 6,6-diMethyl-
  • Cyclopropane-1,1-dicarboxylic Acid cycl-Isopropylidene Ester cycl-Isopropylidene Cyclopropane-1,1-dicarboxylate
  • 6,6-DiMethyl-5,7-dioxaspiro[2.5]octan-4,8-dione
  • cyclic Isopropylidene 1,1-cyclopropanedicarboxylate 99%
  • 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione &gt
  • cyclic Isopropylidene 1,1-cyclopropanedicarboxylate-D4
  • 5617-70-9
  • Organic Building Blocks
  • Lactones
  • Building Blocks
  • Carbonyl Compounds
  • Simple 3-Membered Ring Compounds
  • Dioxanes & Dioxolanes
  • Dioxanes
  • Cyclopropanes
  • Cyclopropanes
  • Dioxanes
  • Dioxanes & Dioxolanes
  • Simple 3-Membered Ring Compounds