ChemicalBook > CAS DataBase List > Purine

Purine

Product Name
Purine
CAS No.
120-73-0
Chemical Name
Purine
Synonyms
9H-PURINE;7H-Purine;1H-Purine;X 128;PURINE;NSC 753;Isopurine;Purine 98%;Purine,99%;beta-Purine
CBNumber
CB6447322
Molecular Formula
C5H4N4
Formula Weight
120.11
MOL File
120-73-0.mol
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Purine Property

Melting point:
214-217 °C (lit.)
Boiling point:
214.09°C (rough estimate)
Density 
1.3106 (rough estimate)
refractive index 
1.7380 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Crystals
pka
2.3(at 20℃)
color 
White
Water Solubility 
400 g/L (20 ºC)
Merck 
7942
BRN 
3200
CAS DataBase Reference
120-73-0(CAS DataBase Reference)
NIST Chemistry Reference
9H-Purine(120-73-0)
EPA Substance Registry System
Purine (120-73-0)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
UO7450000
HS Code 
29335995
Toxicity
LD50 intraperitoneal in rat: 800mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P55805
Product name
Purine
Purity
98%
Packaging
1g
Price
$206
Updated
2024/03/01
Alfa Aesar
Product number
J60999
Product name
Purine, 98%
Packaging
1g
Price
$227
Updated
2024/03/01
TRC
Product number
P840288
Product name
Purine
Packaging
50mg
Price
$50
Updated
2021/12/16
ApexBio Technology
Product number
C6588
Product name
Purine
Packaging
100mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-W008627
Product name
Purine
Purity
>98.0%
Packaging
1g
Price
$65
Updated
2021/12/16
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Purine Chemical Properties,Usage,Production

Chemical Properties

very slightly yellow to cream crystalline powder

Uses

Purine can be used human immunogenic epitopes of H,K, and E human endogenous retroviruses.

Uses

Purine can undergo direct C-H functionalization in the presence of palladium catalyst to form various biologically important products.

Uses

Organic synthesis, metabolism, and biochemi- cal research. (2) One of a number of basic compounds found in living matter and having a purine-type molecular structure.

Definition

ChEBI: The 9H-tautomer of purine.

Definition

A simple nitrogenous organic molecule with a double ring structure. Members of the purine group include adenine and guanine, which are constituents of the nucleic acids, and certain plant alkaloids, such as caffeine and theobromine.

Definition

purine: An organic nitrogenous base(see formula), sparingly soluble inwater, that gives rise to a group ofbiologically important derivatives,notably adenine and guanine,which occur in nucleotides and nucleicacids (DNA and RNA).

Biosynthesis

Basically, the same pathway is found in all organisms capable of purine biosynthesis de novo. The initial substrate is the highly phosphorylated sugar 5-phosphoribosyl-α-1-pyrophosphate (PRPP). An amino group is transferred from glutamine to PRPP catalyzed by the enzyme glutamine PRPP amidotransferase. After that, it takes four reactions to complete the imidazole ring and an additional five reactions to synthesize the pyrimidine moiety and thereby to complete the purine molecule. In some bacteria (e.g., B. subtilis and Escherichia coli), the third step is also catalyzed by a second enzyme (purT) that uses formate instead of a tetrahydrofolic acid derivative as formyl donor. The sixth step has been found to be a two-step reaction, which in some organisms is catalyzed by a single enzyme. The end product of the de novo purine biosynthetic pathway is IMP. After the formation of IMP, purine synthesis splits into two separate pathways leading to the synthesis of AMP and GMP. The control point for feedback inhibition by purine nucleotides and activation by PRPP is on the activity of the first enzyme of the pathway glutamine PRPP amidotransferase. The branching from IMP is regulated by ATP and GTP to ensure a proper balance between ATP and GTP.

General Description

Purine is a heterocyclic organic compound constituting a pyrimidine ring fused to an imidazole ring.

Purification Methods

It crystallises from toluene or EtOH, and sublimes at 100-150o/0.1mm or 160o/10-4mm. The picrate has m 207-209o after crystallisation from 20volumes of H2O. [Beilstein 26 H 354, 26 III/IV 1736.]

Purine Preparation Products And Raw materials

Raw materials

Preparation Products

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Purine Suppliers

BOC Sciences
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View Lastest Price from Purine manufacturers

Career Henan Chemical Co
Product
Purine 120-73-0
Price
US $9.80/KG
Min. Order
1g
Purity
>98%
Supply Ability
20 tons
Release date
2020-02-10

120-73-0, PurineRelated Search:


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