BAY-885

Use In vitro

Product Name: BAY-885
CAS No.: 2307249-33-6
Chemical Name: BAY-885
Synonyms: BAY-885;BAY-885 USP/EP/BP;BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885;[2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone;Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-
CBNumber: CB64667614
Molecular Formula: C25H28F3N7O2
Formula Weight: 515.53
MOL File: 2307249-33-6.mol

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BAY-885 Property

Boiling point:: 685.0±55.0 °C(Predicted)
Density: 1.362±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO:23.33(Max Conc. mg/mL);45.25(Max Conc. mM)
Ethanol:8.0(Max Conc. mg/mL);15.52(Max Conc. mM)
form: A solid
pka: 7.06±0.42(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb611265
Product name: BAY-885
Purity: >98%
Packaging: 10mg
Price: $1208.7
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611265
Product name: BAY-885
Purity: >98%
Packaging: 25mg
Price: $1802
Updated: 2021/12/16

ChemScene

Product number: CS-0043294
Product name: BAY885
Purity: 99.15%
Packaging: 50mg
Price: $2600
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611265
Product name: BAY-885
Purity: >98%
Packaging: 50mg
Price: $2691.1
Updated: 2021/12/16

ChemScene

Product number: CS-0043294
Product name: BAY885
Purity: 99.15%
Packaging: 100mg
Price: $3600
Updated: 2021/12/16

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BAY-885 Chemical Properties,Usage,Production

Use

BAY-885 is a highly potent and selective ERK5 inhibitor.

In vitro

BAY-885 shows potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and has no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM), thereby ruling out potential effects as a general inhibitor of transcription or translation.

BAY-885 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-885 Suppliers

China 28 United States 5 Global 33

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2307249-33-6, BAY-885Related Search:

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BAY-885

[2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone

Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-

BAY-885 USP/EP/BP

BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885

2307249-33-6

C25H28F3N7O2