BAY 2416964

Use In vitro In vivo

Product Name: BAY 2416964
CAS No.: 2242464-44-2
Chemical Name: BAY 2416964
Synonyms: BAY241696;AHR antagonist 3;BAY 2416964 USP/EP/BP;6-(4-chlorophenyl)-N-[(2S)-1-hydroxypropan-2-yl]-2-(1-methylpyrazol-4-yl)-3-oxopyridazine-4-carboxamide;(S)-6-(4-chlorophenyl)-N-(1-hydroxypropan-2-yl)-2-(1-methyl-1H-pyrazol-4-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide;4-Pyridazinecarboxamide, 6-(4-chlorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-2-(1-methyl-1H-pyrazol-4-yl)-3-oxo-
CBNumber: CB15865784
Molecular Formula: C18H18ClN5O3
Formula Weight: 387.82
MOL File: 2242464-44-2.mol

More

Less

BAY 2416964 Property

Density: 1.42±0.1 g/cm3(Predicted)
solubility: DMSO:64.0(Max Conc. mg/mL);165.02(Max Conc. mM)
pka: 11.81±0.20(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0114330
Product name: BAY2416964
Purity: 99.59%
Packaging: 5mg
Price: $280
Updated: 2021/12/16

ChemScene

Product number: CS-0114330
Product name: BAY2416964
Purity: 99.59%
Packaging: 10mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0114330
Product name: BAY2416964
Purity: 99.59%
Packaging: 25mg
Price: $670
Updated: 2021/12/16

ChemScene

Product number: CS-0114330
Product name: BAY2416964
Purity: 99.59%
Packaging: 50mg
Price: $1050
Updated: 2021/12/16

DC Chemicals

Product number: 020439
Product name: BAY2416964
Packaging: 002
Price: $1200
Updated: 2021/12/16

More

Less

BAY 2416964 Chemical Properties,Usage,Production

Use

BAY 2416964 (compound 192) is a potent and orally active antagonist of aryl hydrocarbon receptor (AhR) with IC50 of 341 nM. BAY 2416964 has the potential in the treatment of solid tumors.

In vitro

BAY 2416964 (Example 192) induces AHR-regulated gene CYP1A1 expression with IC50 of 4.30 nM in a human monocytic U937 cells.

In vivo

BAY 2416964 (Example 192) is dissolved in Ethanol/Solutol/Water (10/40/50) and given at 30 mg/kg, QD, p.o.. The efficacy is calculated based on tumor volume. BAY 2416964 (Example 192) is shown to have the potential for solid tumour treatment.

BAY 2416964 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BAY 2416964 Suppliers

China 35 United States 3 Global 38

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3421
Advantage: 58

Qingdao Marine Biomedical Research Institute Co., Ltd.

Tel: 0532-85906825 18366218597
Fax: QQ：1806633058
Email: wizard.s.bzh@163.com
Country: China
ProdList: 25
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9737
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 7565
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

Dezhou LonWel Pharmaceutical Technology Co., Ltd.

Tel: 13761310616
Fax: QQ: 39324283
Email: 39324283@qq.com
Country: China
ProdList: 1946
Advantage: 58

Fujian boshi pharmaceutical technology co. LTD

Tel: 18120708884
Email: 393612455@qq.com
Country: China
ProdList: 255
Advantage: 58

2242464-44-2, BAY 2416964Related Search:

BAY1895344 2HCl BAY-2402234 BAY-1125976. BAY-885 BAY-985 BAY 1316957) BAY-1163877 BAY1895344 HCl BAY-1895344 Benzamide, N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl]-2-ethyl- BAY 2666605 bHLHe76

AHR antagonist 3

(S)-6-(4-chlorophenyl)-N-(1-hydroxypropan-2-yl)-2-(1-methyl-1H-pyrazol-4-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

4-Pyridazinecarboxamide, 6-(4-chlorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-2-(1-methyl-1H-pyrazol-4-yl)-3-oxo-

6-(4-chlorophenyl)-N-[(2S)-1-hydroxypropan-2-yl]-2-(1-methylpyrazol-4-yl)-3-oxopyridazine-4-carboxamide

BAY 2416964 USP/EP/BP

BAY241696

2242464-44-2