BAY-885
Use In vitro- Product Name
- BAY-885
- CAS No.
- 2307249-33-6
- Chemical Name
- BAY-885
- Synonyms
- BAY-885;BAY-885 USP/EP/BP;BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885;[2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone;Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-
- CBNumber
- CB64667614
- Molecular Formula
- C25H28F3N7O2
- Formula Weight
- 515.53
- MOL File
- 2307249-33-6.mol
BAY-885 Property
- Boiling point:
- 685.0±55.0 °C(Predicted)
- Density
- 1.362±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO:23.33(Max Conc. mg/mL);45.25(Max Conc. mM)
Ethanol:8.0(Max Conc. mg/mL);15.52(Max Conc. mM) - form
- A solid
- pka
- 7.06±0.42(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- orb611265
- Product name
- BAY-885
- Purity
- >98%
- Packaging
- 10mg
- Price
- $1208.7
- Updated
- 2021/12/16
- Product number
- orb611265
- Product name
- BAY-885
- Purity
- >98%
- Packaging
- 25mg
- Price
- $1802
- Updated
- 2021/12/16
- Product number
- CS-0043294
- Product name
- BAY885
- Purity
- 99.15%
- Packaging
- 50mg
- Price
- $2600
- Updated
- 2021/12/16
- Product number
- orb611265
- Product name
- BAY-885
- Purity
- >98%
- Packaging
- 50mg
- Price
- $2691.1
- Updated
- 2021/12/16
- Product number
- CS-0043294
- Product name
- BAY885
- Purity
- 99.15%
- Packaging
- 100mg
- Price
- $3600
- Updated
- 2021/12/16
BAY-885 Chemical Properties,Usage,Production
Use
BAY-885 is a highly potent and selective ERK5 inhibitor.
In vitro
BAY-885 shows potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and has no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM), thereby ruling out potential effects as a general inhibitor of transcription or translation.
BAY-885 Preparation Products And Raw materials
Raw materials
Preparation Products
BAY-885 Suppliers
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- 021-52996696，15000506266 15000506266
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