Methyl 4-aminopyridine-3-carboxylate
- Product Name
- Methyl 4-aminopyridine-3-carboxylate
- CAS No.
- 16135-36-7
- Chemical Name
- Methyl 4-aminopyridine-3-carboxylate
- Synonyms
- 3-Pyridinecarboxylic acid, 4-aMino-, Methyl ester;4-Aminonicotinate;RARECHEM AL BF 1386;METHYL-4-AMINONICOTINATE;4-Amino Methyl nicotinate;Methyl4-Aminonicotinate>Methyl4-aminonicotinate,98%;Methyl 4-aminonicotinate 98%;4-AMINONICOTINIC ACID METHYL ESTER;methyl 4-aminopyridine-3-carboxylate
- CBNumber
- CB6467292
- Molecular Formula
- C7H8N2O2
- Formula Weight
- 152.15
- MOL File
- 16135-36-7.mol
Methyl 4-aminopyridine-3-carboxylate Property
- Melting point:
- 172-174℃
- Boiling point:
- 288.7±20.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 7.04±0.12(Predicted)
- color
- White to Almost white
- CAS DataBase Reference
- 16135-36-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- PHB00050
- Product name
- Methyl 4-aminonicotinate
- Purity
- AldrichCPR
- Packaging
- 1 g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- M2303
- Product name
- Methyl 4-Aminonicotinate
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $150
- Updated
- 2025/07/31
- Product number
- M2303
- Product name
- Methyl 4-Aminonicotinate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $598
- Updated
- 2025/07/31
- Product number
- M331128
- Product name
- Methyl 4-Aminonicotinate
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA61456
- Product name
- 4-Aminonicotinic acid methyl ester
- Packaging
- 5G
- Price
- $90
- Updated
- 2021/12/16
Methyl 4-aminopyridine-3-carboxylate Chemical Properties,Usage,Production
Chemical Properties
Off-white solid
Synthesis
280115-84-6
16135-36-7
General procedure for the synthesis of methyl 4-aminonicotinate from methyl 4-((tert-butoxycarbonyl)amino)nicotinate: 4-((tert-butoxycarbonyl)amino)nicotinate (9.08 g, 36.0 mmol) was dissolved in a 50/50 (v/v) trifluoroacetic acid (TFA)/dichloromethane (DCM) mixture (100 mL), and the reaction was stirred at room temperature for 2 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. Subsequently, the concentrate was redissolved in dichloromethane (100 mL), washed with saturated sodium bicarbonate solution, dried over anhydrous sodium sulfate and concentrated again under reduced pressure. Methyl 4-aminonicotinate (5.43 g, 99.1% yield) was finally obtained, the purity of which met the requirements of the subsequent reaction. The mass spectrum (chemical ionization, CI) showed a molecular ion peak (M/E) of 153.1.
References
[1] Patent: WO2003/103575, 2003, A2. Location in patent: Page 74
[2] Patent: WO2005/49604, 2005, A2. Location in patent: Page/Page column 107
[3] Patent: EP1140905, 2003, B1
Methyl 4-aminopyridine-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 4-aminopyridine-3-carboxylate Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from Methyl 4-aminopyridine-3-carboxylate manufacturers
- Product
- Methyl 4-aminopyridine-3-carboxylate 16135-36-7
- Price
- US $70.00-700.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-09
- Product
- Methyl4-Aminonicotinate 16135-36-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- Methyl 4-aminopyridine-3-carboxylate 16135-36-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25