L-745,870 TRIHYDROCHLORIDE

Product Name: L-745,870 TRIHYDROCHLORIDE
CAS No.: 158985-00-3
Chemical Name: L-745,870 TRIHYDROCHLORIDE
Synonyms: 3HCl;L 745870;L 745870,L745870;L-745,870 trihydroch;L-745,870 TRIHYDROCHLORIDE;3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-;3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE
CBNumber: CB6481216
Molecular Formula: C18H19ClN4
Formula Weight: 326.82
MOL File: 158985-00-3.mol

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L-745,870 TRIHYDROCHLORIDE Property

Boiling point:: 571.4±50.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Desiccate at +4°C
solubility: DMSO:16.5(Max Conc. mg/mL);50.49(Max Conc. mM)
pka: 8.20±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 1002
Product name: L-745,870trihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $634
Updated: 2021/12/16

ChemScene

Product number: CS-0003281
Product name: L-745870
Purity: 99.88%
Packaging: 5mg
Price: $82
Updated: 2021/12/16

ChemScene

Product number: CS-0003281
Product name: L-745870
Purity: 99.88%
Packaging: 10mg
Price: $140
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 10MG
Price: $665.81
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 50MG
Price: $1073.29
Updated: 2021/12/16

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L-745,870 TRIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.

Definition

ChEBI: 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine is a member of piperazines.

Biological Activity

A highly potent and selective D 4 dopamine receptor antagonist; L-745,870 has K i values of 0.51, 2300 and 960 nM for D 4 , D 3 and D 2 subtypes respectively and > 1000-fold selectivity over 5-HT 2 , D 1 and D 5 receptors.

L-745,870 TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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L-745,870 TRIHYDROCHLORIDE Suppliers

China 27 Germany 1 Japan 2 United Kingdom 3 United States 7 Global 40

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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Country: China
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Advantage: 69

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UHN Shanghai Research & Development Co., Ltd.

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Country: China
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EMMX Biotechnology LLC

Tel: 888-539-0666
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Tianjin Kailiqi Biotechnology Co., Ltd.

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MQ (shanghai) Pharmaceuticals Co., Ltd.

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TargetMol Chemicals Inc.

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cjbscvictory

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Beijing Jin Ming Biotechnology Co., Ltd.

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Beijing Stronger Science Co., Ltd.

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Email: elsa.hang@strongerscience.com
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158985-00-3, L-745,870 TRIHYDROCHLORIDERelated Search:

hypochlorous acid 1-(2,9-diazabicyclo[4.3.0]nona-2,4,7,10-tetraen-7-yl)-N,N-dimethyl-methanamine 1-(4-Chlorophenyl)piperazine dihydrochloride 1H-Pyrrolo[2,3-b]pyridine, 3-(1-piperazinylmethyl)- 3-METHYL-7-AZAINDOLE 3-([4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]METHYL)-1H-PYRROLO(2,3-B)PYRIDINE HYDROCHLORIDE 7-Azaindole L-745,870 TRIHYDROCHLORIDE

L-745,870 TRIHYDROCHLORIDE

3HCl

3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE

L 745870

3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine

1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-

L-745,870 trihydroch

L 745870,L745870

158985-00-3

C18H22Cl4N4

C18H19N4Cl3HCl